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Ashley S. Harms
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MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration
AS Harms, S Cao, AL Rowse, AD Thome, X Li, LR Mangieri, RQ Cron, ...
Journal of Neuroscience 33 (23), 9592-9600, 2013
3892013
Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology
FE McAlpine, JK Lee, AS Harms, KA Ruhn, M Blurton-Jones, J Hong, ...
Neurobiology of disease 34 (1), 163-177, 2009
2992009
microRNA-155 regulates alpha-synuclein-induced inflammatory responses in models of Parkinson disease
AD Thome, AS Harms, LA Volpicelli-Daley, DG Standaert
Journal of Neuroscience 36 (8), 2383-2390, 2016
2522016
Inhibition of the JAK/STAT pathway protects against α-synuclein-induced neuroinflammation and dopaminergic neurodegeneration
H Qin, JA Buckley, X Li, Y Liu, TH Fox, GP Meares, H Yu, Z Yan, ...
Journal of Neuroscience 36 (18), 5144-5159, 2016
2182016
Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease
AS Harms, AD Thome, Z Yan, AM Schonhoff, GP Williams, X Li, Y Liu, ...
Experimental neurology 300, 179-187, 2018
1862018
α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration
AS Harms, V Delic, AD Thome, N Bryant, Z Liu, S Chandra, ...
Acta neuropathologica communications 5, 1-16, 2017
1742017
Periphery and brain, innate and adaptive immunity in Parkinson’s disease
AS Harms, SA Ferreira, M Romero-Ramos
Acta neuropathologica 141 (4), 527-545, 2021
1692021
CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease
GP Williams, AM Schonhoff, A Jurkuvenaite, NJ Gallups, DG Standaert, ...
Brain 144 (7), 2047-2059, 2021
1532021
COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside
D Sulzer, A Antonini, V Leta, A Nordvig, RJ Smeyne, JE Goldman, ...
npj Parkinson's Disease 6 (1), 18, 2020
1492020
Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats
DK Lewis, AB Johnson, S Stohlgren, A Harms, F Sohrabji
Journal of neuroimmunology 195 (1-2), 47-59, 2008
1332008
Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease
AS Harms, CJ Barnum, KA Ruhn, S Varghese, I Treviño, A Blesch, ...
Molecular Therapy 19 (1), 46-52, 2011
1252011
How can rAAV‐α‐synuclein and the fibril α‐synuclein models advance our understanding of Parkinson's disease?
LA Volpicelli‐Daley, D Kirik, LE Stoyka, DG Standaert, AS Harms
Journal of neurochemistry 139, 131-155, 2016
1162016
The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia
S Cao, DG Standaert, AS Harms
Journal of neuroinflammation 9, 1-11, 2012
1152012
Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response
JK Lee, MK McCoy, AS Harms, KA Ruhn, SJ Gold, MG Tansey
Journal of Neuroscience 28 (34), 8517-8528, 2008
1002008
T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease
GP Williams, DJ Marmion, AM Schonhoff, A Jurkuvenaite, WJ Won, ...
Acta Neuropathologica 139, 855-874, 2020
822020
Innate and adaptive immune responses in Parkinson's disease
AM Schonhoff, GP Williams, ZD Wallen, DG Standaert, AS Harms
Progress in brain research 252, 169-216, 2020
792020
Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease
GP Williams, AM Schonhoff, A Jurkuvenaite, AD Thome, DG Standaert, ...
Journal of neuroinflammation 15, 1-14, 2018
712018
Fractalkine signaling regulates the inflammatory response in an α-synuclein model of Parkinson disease
AD Thome, DG Standaert, AS Harms
PloS one 10 (10), e0140566, 2015
672015
Regulation of microglia effector functions by tumor necrosis factor signaling
AS Harms, JK Lee, TA Nguyen, J Chang, KM Ruhn, I Treviño, MG Tansey
Glia 60 (2), 189-202, 2012
662012
Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain
E Xu, R Boddu, HA Abdelmotilib, A Sokratian, K Kelly, Z Liu, N Bryant, ...
Molecular Neurodegeneration 17, 1-19, 2022
472022
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