| Interferon stimulation creates chromatin marks and establishes transcriptional memory R Kamada, W Yang, Y Zhang, MC Patel, Y Yang, R Ouda, A Dey, ... Proceedings of the National Academy of Sciences 115 (39), E9162-E9171, 2018 | 152 | 2018 |
| Tetramer formation of tumor suppressor protein p53: Structure, function, and applications R Kamada, Y Toguchi, T Nomura, T Imagawa, K Sakaguchi Peptide Science 106 (4), 598-612, 2016 | 130 | 2016 |
| Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivation R Kamada, T Nomura, CW Anderson, K Sakaguchi Journal of biological chemistry 286 (1), 252-258, 2011 | 84 | 2011 |
| Metal-dependent Ser/Thr protein phosphatase PPM family: Evolution, structures, diseases and inhibitors R Kamada, F Kudoh, S Ito, I Tani, JIB Janairo, JG Omichinski, ... Pharmacology & therapeutics 215, 107622, 2020 | 73 | 2020 |
| Enhancement of transcriptional activity of mutant p53 tumor suppressor protein through stabilization of tetramer formation by calix [6] arene derivatives R Kamada, W Yoshino, T Nomura, Y Chuman, T Imagawa, T Suzuki, ... Bioorganic & medicinal chemistry letters 20 (15), 4412-4415, 2010 | 51 | 2010 |
| Specific Detection and Imaging of Enzyme Activity by Signal‐Amplifiable Self‐Assembling 19F MRI Probes K Matsuo, R Kamada, K Mizusawa, H Imai, Y Takayama, M Narazaki, ... Chemistry–A European Journal 19 (38), 12875-12883, 2013 | 43 | 2013 |
| Novel inhibitors targeting PPM1D phosphatase potently suppress cancer cell proliferation S Ogasawara, Y Kiyota, Y Chuman, A Kowata, F Yoshimura, K Tanino, ... Bioorganic & medicinal chemistry 23 (19), 6246-6249, 2015 | 39 | 2015 |
| Oxidation of methionine residue at hydrophobic core destabilizes p53 tetrameric structure T Nomura, R Kamada, I Ito, Y Chuman, Y Shimohigashi, K Sakaguchi Biopolymers: Original Research on Biomolecules 91 (1), 78-84, 2009 | 37 | 2009 |
| Evaluation of transcriptional activity of p53 in individual living mammalian cells T Imagawa, T Terai, Y Yamada, R Kamada, K Sakaguchi Analytical biochemistry 387 (2), 249-256, 2009 | 31 | 2009 |
| Effective cellular morphology analysis for differentiation processes by a fluorescent 1, 3a, 6a-triazapentalene derivative probe in live cells R Kamada, F Tano, F Kudoh, N Kimura, Y Chuman, A Osawa, K Namba, ... PLoS One 11 (8), e0160625, 2016 | 28 | 2016 |
| Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain M Muscolini, E Montagni, S Caristi, T Nomura, R Kamada, S Di Agostino, ... Cell Cycle 8 (20), 3396-3405, 2009 | 21 | 2009 |
| On the role of H3. 3 in retroviral silencing G Wolf, R Rebollo, MM Karimi, AD Ewing, R Kamada, W Wu, B Wu, ... Nature 548 (7665), E1-E3, 2017 | 20 | 2017 |
| Characterization of a C-terminal SUMO-interacting motif present in select PIAS-family proteins M Lussier-Price, XH Mascle, L Cappadocia, R Kamada, K Sakaguchi, ... Structure 28 (5), 573-585. e5, 2020 | 17 | 2020 |
| PPM1D controls nucleolar formation by up-regulating phosphorylation of nucleophosmin Y Kozakai, R Kamada, J Furuta, Y Kiyota, Y Chuman, K Sakaguchi Scientific Reports 6 (1), 33272, 2016 | 17 | 2016 |
| Inhibition of C-terminal truncated PPM1D enhances the effect of doxorubicin on cell viability in human colorectal carcinoma cell line Y Kozakai, R Kamada, Y Kiyota, F Yoshimura, K Tanino, K Sakaguchi Bioorganic & Medicinal Chemistry Letters 24 (24), 5593-5596, 2014 | 13 | 2014 |
| Synergic strategies for the enhanced self-assembly of biomineralization peptides for the synthesis of functional nanomaterials JIB Janairo, T Sakaguchi, K Mine, R Kamada, K Sakaguchi Protein and Peptide Letters 25 (1), 4-14, 2018 | 11 | 2018 |
| Inhibition of Ser/Thr phosphatase PPM1D induces neutrophil differentiation in HL-60 cells R Kamada, F Kudoh, F Yoshimura, K Tanino, K Sakaguchi The journal of biochemistry 162 (4), 303-308, 2017 | 11 | 2017 |
| Inhibition of tumor suppressor protein p53-dependent transcription by a tetramerization domain peptide via hetero-oligomerization J Wada, R Kamada, T Imagawa, Y Chuman, K Sakaguchi Bioorganic & medicinal chemistry letters 22 (8), 2780-2783, 2012 | 10 | 2012 |
| Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine T Nomura, R Kamada, I Ito, K Sakamoto, Y Chuman, K Ishimori, ... Biopolymers 95 (6), 410-419, 2011 | 9 | 2011 |
| Antiproliferative activity of silver nanoplates on human promyelocytic leukemia cell lines T Sakaguchi, K Mine, F Kudoh, R Kamada, K Sakaguchi Chemistry Letters 44 (3), 327-329, 2015 | 8 | 2015 |
