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| Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation A Laurence, CM Tato, TS Davidson, Y Kanno, Z Chen, Z Yao, RB Blank, ... Immunity 26 (3), 371-381, 2007 | 1937 | 2007 |
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| Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells JJ O’Shea, WE Paul Science 327 (5969), 1098-1102, 2010 | 1728 | 2010 |
| Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes MF McDermott, I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, ... Cell 97 (1), 133-144, 1999 | 1666 | 1999 |
| The JAK-STAT pathway: impact on human disease and therapeutic intervention JJ O'Shea, DM Schwartz, AV Villarino, M Gadina, IB McInnes, A Laurence Annual review of medicine 66 (1), 311-328, 2015 | 1514 | 2015 |
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| JAK inhibition as a therapeutic strategy for immune and inflammatory diseases DM Schwartz, Y Kanno, A Villarino, M Ward, M Gadina, JJ O'Shea Nature reviews Drug discovery 16 (12), 843-862, 2017 | 1269 | 2017 |
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| JAK and STAT signaling molecules in immunoregulation and immune-mediated disease JJ O'Shea, R Plenge Immunity 36 (4), 542-550, 2012 | 1159 | 2012 |
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| JAKs and STATs in immunity, immunodeficiency, and cancer JJ O'Shea, SM Holland, LM Staudt New England Journal of Medicine 368 (2), 161-170, 2013 | 927 | 2013 |
