Sendurai A. Mani
Sendurai A. Mani
Associate Director for Translational Oncology, Legorreta Cancer Center at Brown University
Verified email at - Homepage
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The epithelial-mesenchymal transition generates cells with properties of stem cells
SA Mani, W Guo, MJ Liao, EN Eaton, A Ayyanan, AY Zhou, M Brooks, ...
Cell 133 (4), 704-715, 2008
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
J Yang, SA Mani, JL Donaher, S Ramaswamy, RA Itzykson, C Come, ...
cell 117 (7), 927-939, 2004
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways
TT Onder, PB Gupta, SA Mani, J Yang, ES Lander, RA Weinberg
Cancer research 68 (10), 3645-3654, 2008
Guidelines and definitions for research on epithelial–mesenchymal transition
J Yang, P Antin, G Berx, C Blanpain, T Brabletz, M Bronner, K Campbell, ...
Nature reviews Molecular cell biology 21 (6), 341-352, 2020
Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
JH Taube, JI Herschkowitz, K Komurov, AY Zhou, S Gupta, J Yang, ...
Proceedings of the National Academy of Sciences 107 (35), 15449-15454, 2010
Slug and Sox9 cooperatively determine the mammary stem cell state
W Guo, Z Keckesova, JL Donaher, T Shibue, V Tischler, F Reinhardt, ...
Cell 148 (5), 1015-1028, 2012
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
SA Mani, J Yang, M Brooks, G Schwaninger, A Zhou, N Miura, JL Kutok, ...
Proceedings of the National Academy of Sciences 104 (24), 10069-10074, 2007
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer
H Ling, R Spizzo, Y Atlasi, M Nicoloso, M Shimizu, RS Redis, N Nishida, ...
Genome research 23 (9), 1446-1461, 2013
Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
L Tian, A Goldstein, H Wang, H Ching Lo, IK Sun Kim, T Welte, K Sheng, ...
Nature 544 (7649), 250-254, 2017
Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1
J Lu, X Ye, F Fan, L Xia, R Bhattacharya, S Bellister, F Tozzi, E Sceusi, ...
Cancer cell 23 (2), 171-185, 2013
The epithelial-to-mesenchymal transition and cancer stem cells: a coalition against cancer therapies
BG Hollier, K Evans, SA Mani
Journal of mammary gland biology and neoplasia 14, 29-43, 2009
Exploring a new twist on tumor metastasis
J Yang, SA Mani, RA Weinberg
Cancer research 66 (9), 4549-4552, 2006
Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression
CD May, N Sphyris, KW Evans, SJ Werden, W Guo, SA Mani
Breast Cancer Research 13, 1-10, 2011
Stability of the hybrid epithelial/mesenchymal phenotype
MK Jolly, SC Tripathi, D Jia, SM Mooney, M Celiktas, SM Hanash, ...
Oncotarget 7 (19), 27067, 2016
Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44hi/CD24lo/- Stem Cell Phenotype in Human Breast Cancer
T Blick, H Hugo, E Widodo, M Waltham, C Pinto, SA Mani, RA Weinberg, ...
Journal of mammary gland biology and neoplasia 15, 235-252, 2010
Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells
VL Battula, KW Evans, BG Hollier, Y Shi, FC Marini, A Ayyanan, R Wang, ...
Stem cells 28 (8), 1435-1445, 2010
FOXC2 expression links epithelial–mesenchymal transition and stem cell properties in breast cancer
BG Hollier, AA Tinnirello, SJ Werden, KW Evans, JH Taube, TR Sarkar, ...
Cancer research 73 (6), 1981-1992, 2013
Molecular mechanisms of metastasis in breast cancer—clinical applications
M Mego, SA Mani, M Cristofanilli
Nature reviews Clinical oncology 7 (12), 693-701, 2010
Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis
VL Battula, Y Shi, KW Evans, RY Wang, EL Spaeth, RO Jacamo, R Guerra, ...
The Journal of clinical investigation 122 (6), 2066-2078, 2012
Cell type-specific DNA methylation patterns in the human breast
N Bloushtain-Qimron, J Yao, EL Snyder, M Shipitsin, LL Campbell, ...
Proceedings of the National Academy of Sciences 105 (37), 14076-14081, 2008
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