| PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations JC Denny, MD Ritchie, MA Basford, JM Pulley, L Bastarache, ... Bioinformatics 26 (9), 1205-1210, 2010 | 1190 | 2010 |
| Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data JC Denny, L Bastarache, MD Ritchie, RJ Carroll, R Zink, JD Mosley, ... Nature biotechnology 31 (12), 1102-1111, 2013 | 1025 | 2013 |
| Development of a large‐scale de‐identified DNA biobank to enable personalized medicine DM Roden, JM Pulley, MA Basford, GR Bernard, EW Clayton, JR Balser, ... Clinical Pharmacology & Therapeutics 84 (3), 362-369, 2008 | 990 | 2008 |
| Desiderata for controlled medical vocabularies in the twenty-first century JJ Cimino Methods of information in medicine 37 (04/05), 394-403, 1998 | 923 | 1998 |
| The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies CA McCarty, RL Chisholm, CG Chute, IJ Kullo, GP Jarvik, EB Larson, R Li, ... BMC medical genomics 4, 1-11, 2011 | 775 | 2011 |
| Operational implementation of prospective genotyping for personalized medicine: the design of the Vanderbilt PREDICT project JM Pulley, JC Denny, JF Peterson, GR Bernard, CL Vnencak‐Jones, ... Clinical Pharmacology & Therapeutics 92 (1), 87-95, 2012 | 419 | 2012 |
| Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record MD Ritchie, JC Denny, DC Crawford, AH Ramirez, JB Weiner, JM Pulley, ... The American Journal of Human Genetics 86 (4), 560-572, 2010 | 377 | 2010 |
| Circuit party attendance, club drug use, and unsafe sex in gay men AM Mattison, MW Ross, T Wolfson, D Franklin, ... Journal of substance abuse 13 (1-2), 119-126, 2001 | 349 | 2001 |
| The incidentalome: a threat to genomic medicine IS Kohane, DR Masys, RB Altman Jama 296 (2), 212-215, 2006 | 332 | 2006 |
| Tissue factor: an enzyme cofactor and a true receptor JH Morrissey Thrombosis and haemostasis 86 (07), 66-74, 2001 | 315 | 2001 |
| Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome-and phenome-wide studies JC Denny, DC Crawford, MD Ritchie, SJ Bielinski, MA Basford, Y Bradford, ... The American Journal of Human Genetics 89 (4), 529-542, 2011 | 303 | 2011 |
| In silico dissection of cell-type-associated patterns of gene expression in prostate cancer RO Stuart, W Wachsman, CC Berry, J Wang-Rodriguez, L Wasserman, ... Proceedings of the National Academy of Sciences 101 (2), 615-620, 2004 | 250 | 2004 |
| Giving patients access to their medical records via the internet: the PCASSO experience D Masys, D Baker, A Butros, KE Cowles Journal of the American Medical Informatics Association 9 (2), 181-191, 2002 | 241 | 2002 |
| Principles of human subjects protections applied in an opt‐out, de‐identified biobank J Pulley, E Clayton, GR Bernard, DM Roden, DR Masys Clinical and translational science 3 (1), 42-48, 2010 | 237 | 2010 |
| Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping JS Schildcrout, JC Denny, E Bowton, W Gregg, JM Pulley, MA Basford, ... Clinical Pharmacology & Therapeutics 92 (2), 235-242, 2012 | 206 | 2012 |
| Genome-and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk MD Ritchie, JC Denny, RL Zuvich, DC Crawford, JS Schildcrout, ... Circulation 127 (13), 1377-1385, 2013 | 197 | 2013 |
| The use of phenome‐wide association studies (PheWAS) for exploration of novel genotype‐phenotype relationships and pleiotropy discovery SA Pendergrass, K Brown‐Gentry, SM Dudek, ES Torstenson, JL Ambite, ... Genetic epidemiology 35 (5), 410-422, 2011 | 188 | 2011 |
| Use of keyword hierarchies to interpret gene expression patterns DR Masys, JB Welsh, J Lynn Fink, M Gribskov, I Klacansky, J Corbeil Bioinformatics 17 (4), 319-326, 2001 | 183 | 2001 |
| A genome-and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects K Shameer, JC Denny, K Ding, H Jouni, DR Crosslin, M De Andrade, ... Human genetics 133, 95-109, 2014 | 163 | 2014 |
| Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science JC Denny, MD Ritchie, DC Crawford, JS Schildcrout, AH Ramirez, ... Circulation 122 (20), 2016-2021, 2010 | 147 | 2010 |
