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Liu Huolong
Liu Huolong
Senior Engineer, Alexion, AstraZeneca Rare Disease
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Year
Optimization of critical quality attributes in continuous twin-screw wet granulation via design space validated with pilot scale experimental data
H Liu, SC Galbraith, B Ricart, C Stanton, B Smith-Goettler, L Verdi, ...
International Journal of Pharmaceutics 525 (1), 249-263, 2017
662017
Two-compartmental population balance modeling of a pulsed spray fluidized bed granulation based on computational fluid dynamics (CFD) analysis
H Liu, M Li
International Journal of pharmaceutics 475 (1-2), 256-269, 2014
552014
Using the Box–Behnken experimental design to optimise operating parameters in pulsed spray fluidised bed granulation
H Liu, K Wang, W Schlindwein, M Li
International Journal of Pharmaceutics 448 (2), 329-338, 2013
452013
Media formulation optimization: current and future opportunities
SC Galbraith, H Bhatia, H Liu, S Yoon
Current opinion in chemical engineering 22, 42-47, 2018
382018
Design space determination and process optimization in at-scale continuous twin screw wet granulation
H Liu, B Ricart, C Stanton, B Smith-Goettler, L Verdi, T O'Connor, S Lee, ...
Computers & Chemical Engineering 125, 271-286, 2019
352019
Population balance modelling and multi-stage optimal control of a pulsed spray fluidized bed granulation
H Liu, M Li
International Journal of Pharmaceutics 468 (1-2), 223-233, 2014
292014
Integrated modeling of a continuous direct compression tablet manufacturing process: a production scale case study
SC Galbraith, B Cha, Z Huang, S Park, H Liu, RF Meyer, MH Flamm, ...
Powder technology 354, 199-210, 2019
272019
Linking process variables to residence time distribution in a hybrid flowsheet model for continuous direct compression
SC Galbraith, S Park, Z Huang, H Liu, RF Meyer, M Metzger, MH Flamm, ...
Chemical Engineering Research and Design 153, 85-95, 2020
262020
Prediction of critical quality attributes and optimization of continuous dry granulation process via flowsheet modeling and experimental validation
SY Park, SC Galbraith, H Liu, HW Lee, B Cha, Z Huang, T O'Connor, ...
Powder technology 330, 461-470, 2018
252018
Modeling and simulation of continuous powder blending applied to a continuous direct compression process
SC Galbraith, H Liu, B Cha, SY Park, Z Huang, S Yoon
Pharmaceutical Development and Technology 23 (10), 1097-1107, 2018
212018
Three-dimensional computational fluid dynamics (CFD) study of the gas–particle circulation pattern within a fluidized bed granulator: By full factorial design of fluidization …
H Liu, S Yoon, M Li
Drying Technology 35 (9), 1043-1058, 2017
212017
Assessment of spatial heterogeneity in continuous twin screw wet granulation process using three-compartmental population balance model
H Liu, SC Galbraith, SY Park, B Cha, Z Huang, RF Meyer, MH Flamm, ...
Pharmaceutical development and technology 24 (1), 105-117, 2019
172019
A process optimization strategy of a pulsed-spray fluidized bed granulation process based on predictive three-stage population balance model
H Liu, T O'Connor, S Lee, S Yoon
Powder technology 327, 188-200, 2018
172018
Optimization of the manufacturing process of a complex amphotericin B liposomal formulation using quality by design approach
H Liu, B Rivnay, K Avery, JH Myung, D Kozak, N Landrau, A Nivorozhkin, ...
International Journal of Pharmaceutics 585, 119473, 2020
132020
Flowsheet modeling of a continuous direct compression process
S Yoon, S Galbraith, B Cha, H Liu
Computer Aided Chemical Engineering 41, 121-139, 2018
122018
Development of a three-compartmental population balance model for a continuous twin screw wet granulation process
HL Huolong Liu, Shaun C Galbraith, Seo-Young Park, Bumjoon Cha, Zhuangrong ...
Pharmaceutical development and technology, 1-13, 2018
82018
A thermodynamic balance model for liquid film drying kinetics of a tablet film coating and drying process
B Cha, SC Galbraith, H Liu, SY Park, Z Huang, T O’Connor, S Lee, ...
AAPS PharmSciTech 20, 1-13, 2019
72019
Modeling and control of batch pulsed top-spray fluidized bed granulation
H Liu
De Montfort University, 2014
72014
FLOWSHEET MODELING OF A CONTINUOUS DIRECT COMPRESSION TABLETING PROCESS AT PRODUCTION SCALE
SC Galbraith, Z Huang, B Cha, H Liu, S Hurley, MH Flamm, RJ Meyer, ...
FOCAPO 2017, 2017
62017
Transmission network expansion planning by improved simulated annealing approach
X Liu, H Liu, X Zhang, X Zhao
Sop Transactions on power transmission and smart grid 1 (1), 1-8, 2014
62014
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Articles 1–20