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John J Skoko
John J Skoko
Verified email at pitt.edu
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Cited by
Year
When NRF2 talks, who's listening?
N Wakabayashi, SL Slocum, JJ Skoko, S Shin, TW Kensler
Antioxidants & redox signaling 13 (11), 1649-1663, 2010
6402010
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid β secretion
RP Koldamova, IM Lefterov, MD Ikonomovic, J Skoko, PI Lefterov, ...
Journal of Biological Chemistry 278 (15), 13244-13256, 2003
2972003
The benzo [c] phenanthridine alkaloid, sanguinarine, is a selective, cell-active inhibitor of mitogen-activated protein kinase phosphatase-1
A Vogt, A Tamewitz, J Skoko, RP Sikorski, KA Giuliano, JS Lazo
Journal of Biological Chemistry 280 (19), 19078-19086, 2005
2272005
Notch-Nrf2 Axis: Regulation of Nrf2 Gene Expression and Cytoprotection by Notch Signaling
N Wakabayashi, JJ Skoko, DV Chartoumpekis, S Kimura, SL Slocum, ...
Molecular and cellular biology 34 (4), 653-663, 2014
1402014
Redox regulation of Cdc25B by cell-active quinolinediones
M Brisson, T Nguyen, P Wipf, B Joo, BW Day, JS Skoko, EM Schreiber, ...
Molecular pharmacology 68 (6), 1810-1820, 2005
1042005
Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet
SL Slocum, JJ Skoko, N Wakabayashi, S Aja, M Yamamoto, TW Kensler, ...
Archives of biochemistry and biophysics 591, 57-65, 2016
952016
Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms
DL Palliyaguru, DV Chartoumpekis, N Wakabayashi, JJ Skoko, ...
Free Radical Biology and Medicine 101, 116-128, 2016
832016
A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells
A Vogt, PR McDonald, A Tamewitz, RP Sikorski, P Wipf, JJ Skoko III, ...
Molecular cancer therapeutics 7 (2), 330-340, 2008
772008
Development and optimization of high-throughput in vitro protein phosphatase screening assays
MB Tierno, PA Johnston, C Foster, JJ Skoko, SN Shinde, TY Shun, ...
Nature protocols 2 (5), 1134-1144, 2007
742007
Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1
JS Lazo, R Nunes, JJ Skoko, PEQ de Oliveira, A Vogt, P Wipf
Bioorganic & medicinal chemistry 14 (16), 5643-5650, 2006
712006
Peroxiredoxin involvement in the initiation and progression of human cancer
MB Hampton, KA Vick, JJ Skoko, CA Neumann
Antioxidants & redox signaling 28 (7), 591-608, 2018
692018
A peroxidase peroxiredoxin 1-specific redox regulation of the novel FOXO3 microRNA target let-7
BL Hopkins, M Nadler, JJ Skoko, T Bertomeu, A Pelosi, PM Shafaei, ...
Antioxidants & redox signaling 28 (1), 62-77, 2018
632018
MKP-8, a novel MAPK phosphatase that inhibits p38 kinase
SA Vasudevan, J Skoko, K Wang, SM Burlingame, PN Patel, JS Lazo, ...
Biochemical and biophysical research communications 330 (2), 511-518, 2005
592005
Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B
S Keinan, WD Paquette, JJ Skoko, DN Beratan, W Yang, S Shinde, ...
Organic & Biomolecular Chemistry 6 (18), 3256-3263, 2008
562008
Development and implementation of a 384-well homogeneous fluorescence intensity high-throughput screening assay to identify mitogen-activated protein kinase phosphatase-1 dual …
PA Johnston, CA Foster, TY Shun, JJ Skoko, S Shinde, P Wipf, JS Lazo
Assay and drug development technologies 5 (3), 319-332, 2007
502007
Mimicking embedded vasculature structure for 3D cancer on a chip approaches through micromilling
L Wan, J Skoko, J Yu, OB Ozdoganlar, PR LeDuc, CA Neumann
Scientific reports 7 (1), 16724, 2017
402017
Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity
JJ Skoko, N Wakabayashi, K Noda, S Kimura, K Tobita, N Shigemura, ...
Toxicological Sciences 141 (1), 112-119, 2014
352014
Signals getting crossed in the entanglement of redox and phosphorylation pathways: phosphorylation of peroxiredoxin proteins sparks cell signaling
JJ Skoko, S Attaran, CA Neumann
Antioxidants 8 (2), 29, 2019
302019
Biological evaluation of newly synthesized quinoline-5, 8-quinones as Cdc25B inhibitors
J Cossy, D Belotti, M Brisson, JJ Skoko, P Wipf, JS Lazo
Bioorganic & medicinal chemistry 14 (18), 6283-6287, 2006
302006
Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library
JS Lazo, JJ Skoko, S Werner, B Mitasev, A Bakan, F Koizumi, ...
Journal of Pharmacology and Experimental Therapeutics 322 (3), 940-947, 2007
282007
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