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Alexandra Grubman
Alexandra Grubman
Monash University and Australian Regenerative Medicine Institute
Verified email at monash.edu
Title
Cited by
Cited by
Year
A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation
A Grubman, G Chew, JF Ouyang, G Sun, XY Choo, C McLean, ...
Nature neuroscience 22 (12), 2087-2097, 2019
3962019
Oral treatment with CuII (atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis
BR Roberts, NKH Lim, EJ McAllum, PS Donnelly, DJ Hare, PA Doble, ...
Journal of Neuroscience 34 (23), 8021-8031, 2014
1592014
The innate immune molecule, NOD1, regulates direct killing of Helicobacter pylori by antimicrobial peptides
A Grubman, M Kaparakis, J Viala, C Allison, L Badea, A Karrar, IG Boneca, ...
Cellular microbiology 12 (5), 626-639, 2010
1292010
Copper as a key regulator of cell signalling pathways
A Grubman, AR White
Expert reviews in molecular medicine 16, 2014
1132014
Reprogramming roadmap reveals route to human induced trophoblast stem cells
X Liu, JF Ouyang, FJ Rossello, JP Tan, KC Davidson, DS Valdes, ...
Nature 586 (7827), 101-107, 2020
802020
Neuroinflammation and copper in Alzheimer’s disease
XY Choo, L Alukaidey, AR White, A Grubman
International Journal of Alzheimer’s Disease 2013, 2013
632013
Transcriptional signature in microglia associated with Aβ plaque phagocytosis
A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ...
Nature communications 12 (1), 1-22, 2021
622021
Nucleotide oligomerization domain 1 enhances IFN-γ signaling in gastric epithelial cells during Helicobacter pylori infection and exacerbates disease severity
CC Allison, J Ferrand, L McLeod, M Hassan, M Kaparakis-Liaskos, ...
The Journal of Immunology 190 (7), 3706-3715, 2013
622013
TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway
D Moujalled, A Grubman, K Acevedo, S Yang, YD Ke, DM Moujalled, ...
Human molecular genetics 26 (9), 1732-1746, 2017
612017
Kinase inhibitor screening identifies cyclin-dependent kinases and glycogen synthase kinase 3 as potential modulators of TDP-43 cytosolic accumulation during cell stress
D Moujalled, JL James, SJ Parker, GE Lidgerwood, C Duncan, ...
PloS one 8 (6), e67433, 2013
542013
Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass …
DJ Hare, A Grubman, TM Ryan, A Lothian, JR Liddell, R Grimm, ...
Metallomics 5 (12), 1656-1662, 2013
522013
Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43
D Moujalled, JL James, S Yang, K Zhang, C Duncan, DM Moujalled, ...
Human molecular genetics 24 (6), 1655-1669, 2015
512015
Increased metal content in the TDP-43A315T transgenic mouse model of frontotemporal lobar degeneration and amyotrophic lateral sclerosis
TNT Dang, NKH Lim, A Grubman, QX Li, I Volitakis, AR White, PJ Crouch
Frontiers in aging neuroscience 6, 15, 2014
462014
Neuroprotective copper bis (thiosemicarbazonato) complexes promote neurite elongation
L Bica, JR Liddell, PS Donnelly, C Duncan, A Caragounis, I Volitakis, ...
PLoS One 9 (2), e90070, 2014
442014
Vitamin B6 Is Required for Full Motility and Virulence in Helicobacter pylori
A Grubman, A Phillips, M Thibonnier, M Kaparakis-Liaskos, C Johnson, ...
MBio 1 (3), e00112-10, 2010
412010
X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorder
A Grubman, SA James, J James, C Duncan, I Volitakis, JL Hickey, ...
Chemical science 5 (6), 2503-2516, 2014
382014
Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis
KM Kanninen, A Grubman, J Meyerowitz, C Duncan, JL Tan, SJ Parker, ...
PLoS One 8 (3), e58644, 2013
382013
The copper bis (thiosemicarbazone) complex CuII (atsm) is protective against cerebral ischemia through modulation of the inflammatory milieu
MT Huuskonen, Q Tuo, S Loppi, H Dhungana, P Korhonen, LE McInnes, ...
Neurotherapeutics 14 (2), 519-532, 2017
372017
PPARβ/δ‐agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1ΔE9 astrocytes
H Konttinen, I Gureviciene, M Oksanen, A Grubman, S Loppi, ...
Glia 67 (1), 146-159, 2019
362019
ZnII (atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism
EJ McAllum, BR Roberts, JL Hickey, TN Dang, A Grubman, PS Donnelly, ...
Neurobiology of disease 81, 20-24, 2015
342015
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