| Comparison of Cas9 activators in multiple species A Chavez, M Tuttle, BW Pruitt, B Ewen-Campen, R Chari, ... Nature methods 13 (7), 563-567, 2016 | 609 | 2016 |
| Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach R Chari, P Mali, M Moosburner, GM Church Nature methods 12 (9), 823-826, 2015 | 463 | 2015 |
| Cas9 gRNA engineering for genome editing, activation and repression S Kiani, A Chavez, M Tuttle, RN Hall, R Chari, D Ter-Ovanesyan, J Qian, ... Nature methods 12 (11), 1051-1054, 2015 | 377 | 2015 |
| Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers AW Briggs, X Rios, R Chari, L Yang, F Zhang, P Mali, GM Church Nucleic acids research 40 (15), e117-e117, 2012 | 300 | 2012 |
| Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells J Soh, N Okumura, WW Lockwood, H Yamamoto, H Shigematsu, ... PloS one 4 (10), e7464, 2009 | 272 | 2009 |
| Whole-genome analysis and HLA genotyping of enteropathy-type T-cell lymphoma reveals 2 distinct lymphoma subtypes RJ Deleeuw, A Zettl, E Klinker, E Haralambieva, M Trottier, R Chari, Y Ge, ... Gastroenterology 132 (5), 1902-1911, 2007 | 260 | 2007 |
| sgRNA Scorer 2.0: a species-independent model to predict CRISPR/Cas9 activity R Chari, NC Yeo, A Chavez, GM Church ACS synthetic biology 6 (5), 902-904, 2017 | 238 | 2017 |
| High-resolution antibody dynamics of vaccine-induced immune responses U Laserson, F Vigneault, D Gadala-Maria, G Yaari, M Uduman, ... Proceedings of the National Academy of Sciences 111 (13), 4928-4933, 2014 | 205 | 2014 |
| TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer DT Starczynowski, WW Lockwood, S Deléhouzée, R Chari, J Wegrzyn, ... The Journal of clinical investigation 121 (10), 4095-4105, 2011 | 203 | 2011 |
| A general strategy to construct small molecule biosensors in eukaryotes J Feng, BW Jester, CE Tinberg, DJ Mandell, MS Antunes, R Chari, ... elife 4, e10606, 2015 | 178 | 2015 |
| Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations DT Starczynowski, R Morin, A McPherson, J Lam, R Chari, J Wegrzyn, ... Blood, The Journal of the American Society of Hematology 117 (2), 595-607, 2011 | 172 | 2011 |
| Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells L Yang, D Grishin, G Wang, J Aach, CZ Zhang, R Chari, J Homsy, X Cai, ... Nature communications 5 (1), 5507, 2014 | 168 | 2014 |
| DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways EA Vucic, R Chari, KL Thu, IM Wilson, AM Cotton, JY Kennett, M Zhang, ... American journal of respiratory cell and molecular biology 50 (5), 912-922, 2014 | 164 | 2014 |
| Recent advances in array comparative genomic hybridization technologies and their applications in human genetics WW Lockwood, R Chari, B Chi, WL Lam European Journal of Human Genetics 14 (2), 139-148, 2006 | 159 | 2006 |
| Translating cancer ‘omics’ to improved outcomes EA Vucic, KL Thu, K Robison, LA Rybaczyk, R Chari, CE Alvarez, WL Lam Genome research 22 (2), 188-195, 2012 | 148 | 2012 |
| DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers WW Lockwood, R Chari, BP Coe, L Girard, C Macaulay, S Lam, ... Oncogene 27 (33), 4615-4624, 2008 | 146 | 2008 |
| Integrative Genomic Analyses Identify BRF2 as a Novel Lineage-Specific Oncogene in Lung Squamous Cell Carcinoma WW Lockwood, R Chari, BP Coe, KL Thu, C Garnis, CA Malloff, ... PLoS medicine 7 (7), e1000315, 2010 | 135 | 2010 |
| Long non-coding RNAs are expressed in oral mucosa and altered in oral premalignant lesions EA Gibb, KSS Enfield, GL Stewart, KM Lonergan, R Chari, RT Ng, ... Oral oncology 47 (11), 1055-1061, 2011 | 123 | 2011 |
| Effect of active smoking on the human bronchial epithelium transcriptome R Chari, KM Lonergan, RT Ng, C MacAulay, WL Lam, S Lam BMC genomics 8, 1-13, 2007 | 123 | 2007 |
| An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer R Chari, BP Coe, EA Vucic, WW Lockwood, WL Lam BMC systems biology 4, 1-14, 2010 | 95 | 2010 |
