Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities L Belfiore, DN Saunders, M Ranson, KJ Thurecht, G Storm, KL Vine Journal of controlled release 277, 1-13, 2018 | 265 | 2018 |
Translationally controlled tumour protein TCTP is induced early in human colorectal tumours and contributes to the resistance of HCT116 colon cancer cells to 5-FU and oxaliplatin UA Bommer, KL Vine, P Puri, M Engel, L Belfiore, K Fildes, M Batterham, ... Cell Communication and Signaling 15, 1-15, 2017 | 51 | 2017 |
Generation and analysis of 3D cell culture models for drug discovery L Belfiore, B Aghaei, AMK Law, JC Dobrowolski, LJ Raftery, AD Tjandra, ... European Journal of Pharmaceutical Sciences 163, 105876, 2021 | 43 | 2021 |
The P2X7 receptor antagonist Brilliant Blue G reduces serum human interferon-γ in a humanized mouse model of graft-versus-host disease NJ Geraghty, L Belfiore, D Ly, SR Adhikary, SJ Fuller, W Varikatt, ... Clinical & Experimental Immunology 190 (1), 79-95, 2017 | 40 | 2017 |
Enabling high throughput drug discovery in 3D cell cultures through a novel bioprinting workflow M Engel, L Belfiore, B Aghaei, M Sutija SLAS technology 27 (1), 32-38, 2022 | 36 | 2022 |
Quantification of ligand density and stoichiometry on the surface of liposomes using single-molecule fluorescence imaging L Belfiore, LM Spenkelink, M Ranson, AM van Oijen, KL Vine Journal of Controlled Release 278, 80-86, 2018 | 35 | 2018 |
N-alkylated isatins evade P-gp mediated efflux and retain potency in MDR cancer cell lines KL Vine, L Belfiore, L Jones, JM Locke, S Wade, E Minaei, M Ranson Heliyon 2 (1), 2016 | 23 | 2016 |
Increased splenic human CD4+: CD8+ T cell ratios, serum human interferon-γ and intestinal human interleukin-17 are associated with clinical graft-versus-host disease in … NJ Geraghty, L Belfiore, SR Adhikary, SI Alexander, R Sluyter, D Watson Transplant Immunology 54, 38-46, 2019 | 17 | 2019 |
N-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer L Belfiore, DN Saunders, M Ranson, KL Vine Pharmaceutics 12 (7), 641, 2020 | 16 | 2020 |
Development of Ligand-Directed Drug-Loaded Liposomes to Target Heterogeneous Tumour Cell Populations in Metastatic Breast Cancer L Belfiore | 1 | 2019 |
Protocol to create phenotypic primary human hepatocyte cultures using the RASTRUM 3D cell model platform C Yee, YL Chan, R Utama, M Besnier, M Engel, L Belfiore STAR protocols 5 (3), 103234, 2024 | | 2024 |
Enabling high throughput target-based drug discovery in 3D cell cultures through novel bioprinting workflow M Engel, L Belfiore, B Aghaei, M Sutija bioRxiv, 2021.04. 21.440768, 2021 | | 2021 |
Increased splenic human CD4 (+): CD8 (+) T cell ratios NJ Geraghty, L Belfiore, SR Adhikary, SI Alexander, R Sluyter, D Watson | | 2019 |
Pro-inflammatory role of the ATP/P2X7 signalling axis in graft-versus-host disease in humanised mice NJ Geraghty, SR Adhikary, P Cuthbertson, D Ly, T Guy, L Belfiore, ... PURINERGIC SIGNALLING 14, S57-S58, 2018 | | 2018 |
P2X7 polymorphisms and the role of P2X7 in graft-versus-host disease S Adhikary, N Geraghty, L Belfiore, S Alexander, R Sluyter, D Watson EUROPEAN JOURNAL OF IMMUNOLOGY 46, 725-725, 2016 | | 2016 |
P2X7 BLOCKADE REDUCES INTERFERON GAMMA IN A HUMANISED MOUSE MODEL OF GRAFT-VERSUS-HOST DISEASE. N Geraghty, L Belfiore, P Mullany, SR Adhikary, S Alexander, R Sluyter, ... TRANSPLANTATION 99 (11), S5-S5, 2015 | | 2015 |
THE HUMAN IMMUNE RESPONSE IN HUMANISED MICE WITH AND WITHOUT GRAFT-VERSUS-HOST DISEASE (GVHD) W Debbie, G Nicholas, B Lisa, M Phillip, A Stephen, S Ronald IMMUNOLOGY AND CELL BIOLOGY 93 (9), A22-A22, 2015 | | 2015 |
P2X7 RECEPTOR BLOCKADE REDUCES THE CONCENTRATION OF CIRCULATING INTERFERON GAMMA IN A HUMANISED MOUSE MODEL OF GRAFT-VERSUS-HOST DISEASE G Nicholas, B Lisa, M Phillip, A Stephen, S Ronald, W Debbie IMMUNOLOGY AND CELL BIOLOGY 93 (9), A21-A21, 2015 | | 2015 |
TCTP is induced early in colorectal cancer, it is translationally regulated via the Akt/mTORC1 pathway, and it contributes to the resistance of HCT116 colon cancer cells to 5 … UA Bommer, KL Vine, V Iadevaia, L Belfiore, M Engel, P Puri, A Lochhead, ... Febs Journal 282, 95-95, 2015 | | 2015 |
INVESTIGATING THE EFFECTS OF PURINERGIC RECEPTOR (P2X7R) BLOCKADE ON THE DEVELOPMENT OF GRAFT-VERSUS-HOST-DISEASE (GVHD) IN HUMANISED MICE W Debbie, B Lisa, A Stephen, S Ronald IMMUNOLOGY AND CELL BIOLOGY 92 (8), A5-A5, 2014 | | 2014 |