Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance W Huang, A Metlakunta, N Dedousis, P Zhang, I Sipula, JJ Dube, ... diabetes 59 (2), 347-357, 2010 | 600 | 2010 |
Dendritic Cells Promote Macrophage Infiltration and Comprise a Substantial Proportion of Obesity-Associated Increases in CD11c+ Cells in Adipose Tissue and Liver M Stefanovic-Racic, X Yang, MS Turner, BS Mantell, DB Stolz, ... Diabetes 61 (9), 2330-2339, 2012 | 243 | 2012 |
A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels M Stefanovic-Racic, G Perdomo, BS Mantell, IJ Sipula, NF Brown, ... American Journal of Physiology-Endocrinology and Metabolism 294 (5), E969-E977, 2008 | 230 | 2008 |
The mammalian target of rapamycin regulates lipid metabolism in primary cultures of rat hepatocytes NF Brown, M Stefanovic-Racic, IJ Sipula, G Perdomo Metabolism 56 (11), 1500-1507, 2007 | 182 | 2007 |
Hepatocyte growth factor gene therapy for pancreatic islets in diabetes: reducing the minimal islet transplant mass required in a glucocorticoid-free rat model of allogeneic … JC Lopez-Talavera, A Garcia-Ocaña, I Sipula, KK Takane, ... Endocrinology 145 (2), 467-474, 2004 | 154 | 2004 |
Rapamycin-mediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation IJ Sipula, NF Brown, G Perdomo Metabolism 55 (12), 1637-1644, 2006 | 134 | 2006 |
Mice Lacking NKT Cells but with a Complete Complement of CD8+ T-Cells Are Not Protected against the Metabolic Abnormalities of Diet-Induced Obesity BS Mantell, M Stefanovic-Racic, X Yang, N Dedousis, IJ Sipula, ... PloS one 6 (6), e19831, 2011 | 124 | 2011 |
Tregs facilitate obesity and insulin resistance via a Blimp-1/IL-10 axis LY Beppu, RGR Mooli, X Qu, GJ Marrero, CA Finley, AN Fooks, ZP Mullen, ... JCI insight 6 (3), 2021 | 73 | 2021 |
Cholesterol sulfate and cholesterol sulfotransferase inhibit gluconeogenesis by targeting hepatocyte nuclear factor 4α X Shi, Q Cheng, L Xu, J Yan, M Jiang, J He, M Xu, M Stefanovic-Racic, ... Molecular and cellular biology, 2014 | 49 | 2014 |
Nrf2 deletion from adipocytes, but not hepatocytes, potentiates systemic metabolic dysfunction after long-term high-fat diet-induced obesity in mice DV Chartoumpekis, DL Palliyaguru, N Wakabayashi, M Fazzari, ... American Journal of Physiology-Endocrinology and Metabolism 315 (2), E180-E195, 2018 | 46 | 2018 |
Abnormal lipid processing but normal long-term repopulation potential of myc−/− hepatocytes LR Edmunds, PA Otero, L Sharma, S D'souza, JM Dolezal, S David, J Lu, ... Oncotarget 7 (21), 30379, 2016 | 37 | 2016 |
Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice DV Chartoumpekis, Y Yagishita, M Fazzari, DL Palliyaguru, UNM Rao, ... JCI insight 3 (5), 2018 | 32 | 2018 |
DNA methylation alters transcriptional rates of differentially expressed genes and contributes to pathophysiology in mice fed a high fat diet P Zhang, T Chu, N Dedousis, BS Mantell, I Sipula, L Li, KD Bunce, ... Molecular Metabolism 6 (4), 327-339, 2017 | 32 | 2017 |
Liver-specific Prkn knockout mice are more susceptible to diet-induced hepatic steatosis and insulin resistance LR Edmunds, B Xie, AM Mills, BR Huckestein, R Undamatla, A Murali, ... Molecular Metabolism 41, 101051, 2020 | 31 | 2020 |
Kupffer cells facilitate the acute effects of leptin on hepatic lipid metabolism A Metlakunta, W Huang, M Stefanovic-Racic, N Dedousis, I Sipula, ... American Journal of Physiology-Endocrinology and Metabolism 312 (1), E11-E18, 2017 | 31 | 2017 |
Hepatocyte-specific ablation or whole-body inhibition of xanthine oxidoreductase in mice corrects obesity-induced systemic hyperuricemia without improving metabolic abnormalities DB Harmon, WK Mandler, IJ Sipula, N Dedousis, SE Lewis, JT Eckels, ... Diabetes 68 (6), 1221-1229, 2019 | 30 | 2019 |
Similar degrees of obesity induced by diet or aging cause strikingly different immunologic and metabolic outcomes KB Krishna, M Stefanovic‐Racic, N Dedousis, I Sipula, RM O'Doherty Physiological reports 4 (6), e12708, 2016 | 24 | 2016 |
Mitochondrial energetics in skeletal muscle are associated with leg power and cardiorespiratory fitness in the study of muscle, mobility and aging T Mau, LY Lui, G Distefano, PA Kramer, SV Ramos, FGS Toledo, ... The Journals of Gerontology: Series A 78 (8), 1367-1375, 2023 | 21 | 2023 |
Adipose tissue-derived free fatty acids initiate myeloid cell accumulation in mouse liver in states of lipid oversupply DB Harmon, C Wu, N Dedousis, IJ Sipula, M Stefanovic-Racic, ... American Journal of Physiology-Endocrinology and Metabolism 315 (5), E758-E770, 2018 | 17 | 2018 |
Reduced mitophagy is an early feature of NAFLD and liver-specific PARKIN knockout hastens the onset of steatosis, inflammation and fibrosis R Undamatla, OG Fagunloye, J Chen, LR Edmunds, A Murali, A Mills, ... Scientific Reports 13 (1), 7575, 2023 | 13 | 2023 |