Hai-Hui Xue
Hai-Hui Xue
Member, Hackensack University Medical Center
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Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
SJ Im, M Hashimoto, MY Gerner, J Lee, HT Kissick, MC Burger, Q Shan, ...
Nature 537 (7620), 417-421, 2016
Differentiation and persistence of memory CD8+ T cells depend on T cell factor 1
X Zhou, S Yu, DM Zhao, JT Harty, VP Badovinac, HH Xue
Immunity 33 (2), 229-240, 2010
LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6
YS Choi, JA Gullicksrud, S Xing, Z Zeng, Q Shan, F Li, PE Love, W Peng, ...
Nature immunology 16 (9), 980-990, 2015
Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8+ T cell differentiation
TC Wirth, HH Xue, D Rai, JT Sabel, T Bair, JT Harty, VP Badovinac
Immunity 33 (1), 128-140, 2010
TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow
Q Yang, F Li, C Harly, S Xing, L Ye, X Xia, H Wang, X Wang, S Yu, X Zhou, ...
Nature immunology 16 (10), 1044-1050, 2015
IL-2 negatively regulates IL-7 receptor α chain expression in activated T lymphocytes
HH Xue, PE Kovanen, CA Pise-Masison, M Berg, MF Radovich, JN Brady, ...
Proceedings of the National Academy of Sciences 99 (21), 13759-13764, 2002
Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity
S Xing, F Li, Z Zeng, Y Zhao, S Yu, Q Shan, Y Li, FC Phillips, PK Maina, ...
Nature immunology 17 (6), 695-703, 2016
The TCF-1 and LEF-1 transcription factors have cooperative and opposing roles in T cell development and malignancy
S Yu, X Zhou, FC Steinke, C Liu, SC Chen, O Zagorodna, X Jing, ...
Immunity 37 (5), 813-826, 2012
Constitutive activation of Wnt signaling favors generation of memory CD8 T cells
DM Zhao, S Yu, X Zhou, JS Haring, W Held, VP Badovinac, JT Harty, ...
The Journal of Immunology 184 (3), 1191-1199, 2010
IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo
GR Starbeck-Miller, HH Xue, JT Harty
Journal of Experimental Medicine 211 (1), 105-120, 2014
TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells
FC Steinke, S Yu, X Zhou, B He, W Yang, B Zhou, H Kawamoto, J Zhu, ...
Nature immunology 15 (7), 646-656, 2014
GA binding protein regulates interleukin 7 receptor α-chain gene expression in T cells
HH Xue, J Bollenbacher, V Rovella, R Tripuraneni, YB Du, CY Liu, ...
Nature immunology 5 (10), 1036-1044, 2004
CD8+ T lymphocyte self-renewal during effector cell determination
WHW Lin, SA Nish, B Yen, YH Chen, WC Adams, R Kratchmarov, ...
Cell reports 17 (7), 1773-1782, 2016
The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage
Q Shan, Z Zeng, S Xing, F Li, SM Hartwig, JA Gullicksrud, SP Kurup, ...
Nature immunology 18 (8), 931-939, 2017
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity
S Gautam, J Fioravanti, W Zhu, JB Le Gall, P Brohawn, NE Lacey, J Hu, ...
Nature immunology 20 (3), 337-349, 2019
TCF1 in T cell immunity: a broadened frontier
X Zhao, Q Shan, HH Xue
Nature Reviews Immunology 22 (3), 147-157, 2022
Cutting edge: generation of memory precursors and functional memory CD8+ T cells depends on T cell factor-1 and lymphoid enhancer-binding factor-1
X Zhou, HH Xue
The Journal of Immunology 189 (6), 2722-2726, 2012
CD4+ T cell effector commitment coupled to self-renewal by asymmetric cell divisions
SA Nish, KD Zens, R Kratchmarov, WHW Lin, WC Adams, YH Chen, ...
Journal of Experimental Medicine 214 (1), 39-47, 2017
Little to no expression of angiotensin‐converting enzyme‐2 on most human peripheral blood immune cells but highly expressed on tissue macrophages
X Song, W Hu, H Yu, L Zhao, Y Zhao, X Zhao, HH Xue, Y Zhao
Cytometry Part A 103 (2), 136-145, 2023
Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses
J Yang, X Lin, Y Pan, J Wang, P Chen, H Huang, HH Xue, J Gao, ...
Elife 5, e17936, 2016
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