| Senolytics improve physical function and increase lifespan in old age M Xu, T Pirtskhalava, JN Farr, BM Weigand, AK Palmer, MM Weivoda, ... Nature medicine 24 (8), 1246-1256, 2018 | 1664 | 2018 |
| Targeting cellular senescence prevents age-related bone loss in mice JN Farr, M Xu, MM Weivoda, DG Monroe, DG Fraser, JL Onken, ... Nature medicine 23 (9), 1072-1079, 2017 | 910 | 2017 |
| Cellular senescence drives age-dependent hepatic steatosis M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ... Nature communications 8 (1), 15691, 2017 | 779 | 2017 |
| Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice CM Roos, B Zhang, AK Palmer, MB Ogrodnik, T Pirtskhalava, NM Thalji, ... Aging cell 15 (5), 973-977, 2016 | 674 | 2016 |
| JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age M Xu, T Tchkonia, H Ding, M Ogrodnik, ER Lubbers, T Pirtskhalava, ... Proceedings of the National Academy of Sciences 112 (46), E6301-E6310, 2015 | 671 | 2015 |
| Targeting senescent cells alleviates obesity‐induced metabolic dysfunction AK Palmer, M Xu, YI Zhu, T Pirtskhalava, MM Weivoda, CM Hachfeld, ... Aging cell 18 (3), e12950, 2019 | 455 | 2019 |
| Identification of senescent cells in the bone microenvironment JN Farr, DG Fraser, H Wang, K Jaehn, MB Ogrodnik, MM Weivoda, ... Journal of Bone and Mineral Research 31 (11), 1920-1929, 2016 | 429 | 2016 |
| Obesity-induced cellular senescence drives anxiety and impairs neurogenesis M Ogrodnik, YI Zhu, LGP Langhi, T Tchkonia, P Krüger, E Fielder, ... Cell metabolism 29 (5), 1061-1077. e8, 2019 | 412 | 2019 |
| Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ... The EMBO journal 38 (5), e100492, 2019 | 374 | 2019 |
| Transplanted senescent cells induce an osteoarthritis-like condition in mice M Xu, EW Bradley, MM Weivoda, SM Hwang, T Pirtskhalava, T Decklever, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 336 | 2017 |
| Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice M Ogrodnik, SA Evans, E Fielder, S Victorelli, P Kruger, H Salmonowicz, ... Aging cell 20 (2), e13296, 2021 | 218 | 2021 |
| The bystander effect contributes to the accumulation of senescent cells in vivo PFL da Silva, M Ogrodnik, O Kucheryavenko, J Glibert, S Miwa, ... Aging cell 18 (1), e12848, 2019 | 190 | 2019 |
| Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction S Victorelli, A Lagnado, J Halim, W Moore, D Talbot, K Barrett, J Chapman, ... The EMBO journal 38 (23), e101982, 2019 | 163 | 2019 |
| Dynamic JUNQ inclusion bodies are asymmetrically inherited in mammalian cell lines through the asymmetric partitioning of vimentin M Ogrodnik, H Salmonowicz, R Brown, J Turkowska, W Średniawa, ... Proceedings of the National Academy of Sciences 111 (22), 8049-8054, 2014 | 154 | 2014 |
| Increased renal cellular senescence in murine high-fat diet: effect of the senolytic drug quercetin SR Kim, K Jiang, M Ogrodnik, X Chen, XY Zhu, H Lohmeier, L Ahmed, ... Translational Research 213, 112-123, 2019 | 149 | 2019 |
| Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cells M Ogrodnik, H Salmonowicz, VN Gladyshev Aging cell 18 (1), e12841, 2019 | 147 | 2019 |
| SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair G Hewitt, B Carroll, R Sarallah, C Correia-Melo, M Ogrodnik, G Nelson, ... Autophagy 12 (10), 1917-1930, 2016 | 145 | 2016 |
| Cellular aging beyond cellular senescence: Markers of senescence prior to cell cycle arrest in vitro and in vivo M Ogrodnik Aging cell 20 (4), e13338, 2021 | 142 | 2021 |
| Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner A Lagnado, J Leslie, MH Ruchaud‐Sparagano, S Victorelli, P Hirsova, ... The EMBO journal 40 (9), e106048, 2021 | 115 | 2021 |
| Quercetin reverses cardiac systolic dysfunction in mice fed with a high-fat diet: role of angiogenesis S Yu, SR Kim, K Jiang, M Ogrodnik, XY Zhu, CM Ferguson, T Tchkonia, ... Oxidative medicine and cellular longevity 2021, 1-11, 2021 | 93 | 2021 |
