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Cheng Zhu
Cheng Zhu
Associate Director, GSK
Verified email at gsk.com
Title
Cited by
Cited by
Year
Drug repositioning for orphan diseases
D Sardana, C Zhu, M Zhang, RC Gudivada, L Yang, AG Jegga
Briefings in bioinformatics 12 (4), 346-356, 2011
2552011
Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death
X Zhang, X Wang, H Zhu, C Zhu, Y Wang, WT Pu, AG Jegga, GC Fan
Journal of molecular and cellular cardiology 49 (5), 841-850, 2010
2092010
The orphan disease networks
M Zhang, C Zhu, A Jacomy, LJ Lu, AG Jegga
The American Journal of Human Genetics 88 (6), 755-766, 2011
772011
RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
M Zelic, F Pontarelli, L Woodworth, C Zhu, A Mahan, Y Ren, M LaMorte, ...
Cell reports 35 (6), 2021
572021
Genome‐wide association mapping of natural variation in odour‐guided behaviour in Drosophila
EB Brown, JE Layne, C Zhu, AG Jegga, SM Rollmann
Genes, Brain and Behavior 12 (5), 503-515, 2013
312013
A vertex similarity-based framework to discover and rank orphan disease-related genes
C Zhu, A Kushwaha, K Berman, AG Jegga
BMC systems biology 6, 1-9, 2012
262012
Computational approaches for human disease gene prediction and ranking
C Zhu, C Wu, BJ Aronow, AG Jegga
Systems Analysis of Human Multigene Disorders, 69-84, 2013
222013
Correction of cilia structure and function alleviates multi-organ pathology in Bardet–Biedl syndrome mice
H Husson, NO Bukanov, S Moreno, MM Smith, B Richards, C Zhu, ...
Human Molecular Genetics 29 (15), 2508-2522, 2020
132020
An integrative network-based approach for drug target indication expansion
Y Han, C Wang, K Klinger, DK Rajpal, C Zhu
PloS one 16 (7), e0253614, 2021
92021
Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform
Y Han, K Klinger, DK Rajpal, C Zhu, E Teeple
BMC bioinformatics 23 (1), 232, 2022
52022
Genome-Wide Polygenic Risk Score Identifies Individuals at Elevated Parkinson’s Disease Risk
Y Han, E Teeple, S Shankara, M Sadeghi, C Zhu, D Liu, FinnGen, ...
MedRxiv, 2020.10. 16.20212944, 2020
52020
Network biology methods for drug repositioning
C Zhu, C Wu, AG Jegga
Post-Genomic Approaches in Drug and Vaccine Development, 115-131, 2022
42022
Genome-Wide Polygenic Risk Score Identifies Individuals at Elevated Parkinson’s Disease Risk (4286)
Y Han, E Teeple, S Shankara, M Sadeghi, C Zhu, D Liu, C Wang, F Frau, ...
Neurology 96 (15 Supplement), 2021
42021
Integrative literature and data mining to rank disease candidate genes
C Wu, C Zhu, AG Jegga
Biomedical Literature Mining, 207-226, 2014
22014
Orphan diseases, bioinformatics and drug discovery
AG Jegga, C Zhu, BJ Aronow
Pediatric Biomedical Informatics: Computer Applications in Pediatric …, 2012
12012
RGS1 Modulates Autophagic and Metabolic Programs and Is a Critical Mediator of Human Regulatory T Cell Function
AL Flynn, J Gans, J Escobedo, C Zhu, AM Florescu, S Shankara, ...
The Journal of Immunology, 2023
2023
RIPK1 activation mediates disease progression in multiple sclerosis by driving neuroinflammatory signaling in microglia and astrocytes
M Zelic, F Pontarelli, A Blazier, L Woodworth, C Zhu, A Mahan, Y Ren, ...
MULTIPLE SCLEROSIS JOURNAL 29, 243-244, 2023
2023
The Lupus Epigenome Relates to Genetics, Transcription and Serological Profiles with Dependency on Molecular Subtypes and Informs Drug Discovery
O Castellini-Pérez, G Barturen, M Martínez-Bueno, A Iakovliev, M Kerick, ...
medRxiv, 2023.01. 19.22283772, 2023
2023
Supplementary Material Correction of cilia structure and function alleviates multi-organ pathology in Bardet-Biedl Syndrome mice
H Husson, NO Bukanov, S Moreno, MM Smith, B Richards, C Zhu, ...
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