Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype DW Threadgill, AA Dlugosz, LA Hansen, T Tennenbaum, U Lichti, D Yee, ... Science 269 (5221), 230-234, 1995 | 1765 | 1995 |
The Collaborative Cross, a community resource for the genetic analysis of complex traits Nature genetics 36 (11), 1133-1137, 2004 | 1098 | 2004 |
Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains SS Moy, JJ Nadler, NB Young, A Perez, LP Holloway, RP Barbaro, ... Behavioural brain research 176 (1), 4-20, 2007 | 836 | 2007 |
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function EJ Chesler, L Lu, S Shou, Y Qu, J Gu, J Wang, HC Hsu, JD Mountz, ... Nature genetics 37 (3), 233-242, 2005 | 792 | 2005 |
The nature and identification of quantitative trait loci: a community’s view Nature Reviews Genetics 4, 911-916, 2003 | 520* | 2003 |
EGF receptor is required for KRAS-induced pancreatic tumorigenesis CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ... Cancer cell 22 (3), 304-317, 2012 | 498 | 2012 |
The genome architecture of the Collaborative Cross mouse genetic reference population Collaborative Cross Consortium Genetics 190 (2), 389-401, 2012 | 422 | 2012 |
Genomic analysis of the major bovine milk protein genes DW Threadgill, JE Womack Nucleic acids research 18 (23), 6935-6942, 1990 | 388 | 1990 |
Luteinizing hormone-dependent activation of the epidermal growth factor network is essential for ovulation M Hsieh, D Lee, S Panigone, K Horner, R Chen, A Theologis, DC Lee, ... Molecular and cellular biology 27 (5), 1914-1924, 2007 | 369 | 2007 |
Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men H Nishimura, E Yerkes, K Hohenfellner, Y Miyazaki, J Ma, TE Hunley, ... Molecular cell 3 (1), 1-10, 1999 | 363 | 1999 |
Genetic analysis of complex traits in the emerging Collaborative Cross DL Aylor, W Valdar, W Foulds-Mathes, RJ Buus, RA Verdugo, RS Baric, ... Genome research 21 (8), 1213-1222, 2011 | 357 | 2011 |
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer S Kaiser, YK Park, JL Franklin, RB Halberg, M Yu, WJ Jessen, ... Genome biology 8, 1-26, 2007 | 352 | 2007 |
A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota-and Butyrate-Dependent MannerFiber–Microbiota–Butyrate Axis … DR Donohoe, D Holley, LB Collins, SA Montgomery, AC Whitmore, ... Cancer discovery 4 (12), 1387-1397, 2014 | 343 | 2014 |
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis RB Roberts, LU Min, MK Washington, SJ Olsen, SH Settle, RJ Coffey, ... Proceedings of the National Academy of Sciences 99 (3), 1521-1526, 2002 | 318 | 2002 |
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics EJ Chesler, DR Miller, LR Branstetter, LD Galloway, BL Jackson, ... Mammalian Genome 19, 382-389, 2008 | 272 | 2008 |
EGFR signaling promotes TGFβ-dependent renal fibrosis J Chen, JK Chen, K Nagai, D Plieth, M Tan, TC Lee, DW Threadgill, ... Journal of the American Society of Nephrology 23 (2), 215-224, 2012 | 261 | 2012 |
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. LA Hansen, N Alexander, ME Hogan, JP Sundberg, A Dlugosz, ... The American journal of pathology 150 (6), 1959, 1997 | 258 | 1997 |
Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain DW Threadgill, D Yee, A Matin, JH Nadeau, T Magnuson Mammalian Genome 8, 390-393, 1997 | 255 | 1997 |
The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics A Roberts, F Pardo-Manuel de Villena, W Wang, L McMillan, ... Mammalian Genome 18, 473-481, 2007 | 250 | 2007 |
Activation of the Epidermal Growth Factor Receptor Signal Transduction Pathway Stimulates Tyrosine Phosphorylation of Protein Kinase C δ (∗) MF Denning, AA Dlugosz, DW Threadgill, T Magnuson, SH Yuspa Journal of Biological Chemistry 271 (10), 5325-5331, 1996 | 243 | 1996 |