Identification of miR-145 and miR-146a as mediators of the 5q–syndrome phenotype DT Starczynowski, F Kuchenbauer, B Argiropoulos, S Sung, R Morin, ... Nature medicine 16 (1), 49-58, 2010 | 836 | 2010 |
Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo C Yu, AB Cantor, H Yang, C Browne, RA Wells, Y Fujiwara, SH Orkin The Journal of experimental medicine 195 (11), 1387-1395, 2002 | 739 | 2002 |
Improved telomere detection using a telomere repeat probe (TTAGGG) n generated by PCR. JW Ijdo, RA Wells, A Baldini, ST Reeders Nucleic acids research 19 (17), 4780, 1991 | 685 | 1991 |
Origin of human chromosome 2: an ancestral telomere-telomere fusion. JW Ijdo, A Baldini, DC Ward, ST Reeders, RA Wells Proceedings of the National Academy of Sciences 88 (20), 9051-9055, 1991 | 490 | 1991 |
Ravulizumab (ALXN1210) vs eculizumab in C5-inhibitor–experienced adult patients with PNH: the 302 study AG Kulasekararaj, A Hill, ST Rottinghaus, S Langemeijer, R Wells, ... Blood, The Journal of the American Society of Hematology 133 (6), 540-549, 2019 | 365 | 2019 |
Fusion of retinoic acid receptor α to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia RA Wells, C Catzavelos, S Kamel-Reid Nature genetics 17 (1), 109-113, 1997 | 356 | 1997 |
Tet2 restrains inflammatory gene expression in macrophages AH Cull, B Snetsinger, R Buckstein, RA Wells, MJ Rauh Experimental hematology 55, 56-70. e13, 2017 | 280 | 2017 |
GATA-1 converts lymphoid and myelomonocytic progenitors into the megakaryocyte/erythrocyte lineages H Iwasaki, S Mizuno, RA Wells, AB Cantor, S Watanabe, K Akashi Immunity 19 (3), 451-462, 2003 | 265 | 2003 |
An inflammatory environment containing TNFα favors Tet2-mutant clonal hematopoiesis SO Abegunde, R Buckstein, RA Wells, MJ Rauh Experimental hematology 59, 60-65, 2018 | 211 | 2018 |
Oral cedazuridine/decitabine for MDS and CMML: a phase 2 pharmacokinetic/pharmacodynamic randomized crossover study G Garcia-Manero, EA Griffiths, DP Steensma, GJ Roboz, R Wells, ... Blood, The Journal of the American Society of Hematology 136 (6), 674-683, 2020 | 190 | 2020 |
Hypervariable minisatellites: recombinators or innocent bystanders? AP Jarman, RA Wells Trends in Genetics 5, 367-371, 1989 | 182 | 1989 |
Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells BZ Carter, M Gronda, Z Wang, K Welsh, C Pinilla, M Andreeff, ... Blood 105 (10), 4043-4050, 2005 | 178 | 2005 |
A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer … M Crump, D Hedley, S Kamel-Reid, B Leber, R Wells, J Brandwein, ... Leukemia & lymphoma 51 (2), 252-260, 2010 | 116 | 2010 |
Patient‐related factors independently impact overall survival in patients with myelodysplastic syndromes: an MDS‐CAN prospective study R Buckstein, RA Wells, N Zhu, HA Leitch, TJ Nevill, KWL Yee, B Leber, ... British journal of haematology 174 (1), 88-101, 2016 | 97 | 2016 |
Practical recommendations on the use of lenalidomide in the management of myelodysplastic syndromes A Giagounidis, P Fenaux, GJ Mufti, P Muus, U Platzbecker, G Sanz, ... Annals of hematology 87, 345-352, 2008 | 96 | 2008 |
Progression of myelodysplasia to acute lymphoblastic leukaemia: implications for disease biology P Disperati, CV Ichim, D Tkachuk, K Chun, AC Schuh, RA Wells Leukemia research 30 (2), 233-239, 2006 | 95 | 2006 |
Disease biology rather than age is the most important determinant of survival of patients≥ 60 years with acute myeloid leukemia treated with uniform intensive therapy V Gupta, K Chun, QL Yi, M Minden, A Schuh, R Wells, J Brandwein Cancer: Interdisciplinary International Journal of the American Cancer …, 2005 | 92 | 2005 |
A new variant translocation in acute promyelocytic leukaemia: molecular characterization and clinical correlation. RA Wells, JL Hummel, A De Koven, A Zipursky, M Kirby, I Dube, ... Leukemia 10 (4), 735-740, 1996 | 92 | 1996 |
Telomere-related sequences at interstitial sites in the human genome RA Wells, GG Germino, S Krishna, VJ Buckle, ST Reeders Genomics 8 (4), 699-704, 1990 | 90 | 1990 |
Ravulizumab (ALXN1210) in patients with paroxysmal nocturnal hemoglobinuria: results of 2 phase 1b/2 studies A Röth, ST Rottinghaus, A Hill, ES Bachman, JS Kim, H Schrezenmeier, ... Blood advances 2 (17), 2176-2185, 2018 | 87 | 2018 |