| BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment GE Winter, A Mayer, DL Buckley, MA Erb, JE Roderick, S Vittori, JM Reyes, ... Molecular cell 67 (1), 5-18. e19, 2017 | 421 | 2017 |
| Dual targeting of oncogenic activation and inflammatory signaling increases therapeutic efficacy in myeloproliferative neoplasms M Kleppe, R Koche, L Zou, P van Galen, CE Hill, L Dong, S De Groote, ... Cancer cell 33 (1), 29-43. e7, 2018 | 289 | 2018 |
| Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands LN Gechijian, DL Buckley, MA Lawlor, JM Reyes, J Paulk, CJ Ott, ... Nature chemical biology 14 (4), 405-412, 2018 | 226 | 2018 |
| Loss of Dnmt3a immortalizes hematopoietic stem cells in vivo M Jeong, HJ Park, H Celik, EL Ostrander, JM Reyes, A Guzman, ... Cell reports 23 (1), 1-10, 2018 | 210 | 2018 |
| Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma R Zeid, MA Lawlor, E Poon, JM Reyes, M Fulciniti, MA Lopez, TG Scott, ... Nature genetics 50 (4), 515-523, 2018 | 210 | 2018 |
| Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis AD Viny, CJ Ott, B Spitzer, M Rivas, C Meydan, E Papalexi, D Yelin, ... Journal of Experimental Medicine 212 (11), 1819-1832, 2015 | 162 | 2015 |
| High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program DP Labbé, G Zadra, M Yang, JM Reyes, CY Lin, S Cacciatore, EM Ebot, ... Nature communications 10 (1), 4358, 2019 | 156 | 2019 |
| Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer S Shu, HJ Wu, YG Jennifer, R Zeid, IS Harris, B Jovanović, K Murphy, ... Molecular cell 78 (6), 1096-1113. e8, 2020 | 145 | 2020 |
| Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer H Zhang, J Qi, JM Reyes, L Li, PK Rao, F Li, CY Lin, JA Perry, MA Lawlor, ... Cancer discovery 6 (9), 1006-1021, 2016 | 126 | 2016 |
| PI3K/AKT signaling regulates H3K4 methylation in breast cancer JM Spangle, KM Dreijerink, AC Groner, H Cheng, CE Ohlson, J Reyes, ... Cell reports 15 (12), 2692-2704, 2016 | 106 | 2016 |
| Large DNA methylation nadirs anchor chromatin loops maintaining hematopoietic stem cell identity X Zhang, M Jeong, X Huang, XQ Wang, X Wang, W Zhou, MS Shamim, ... Molecular cell 78 (3), 506-521. e6, 2020 | 82 | 2020 |
| Enhancer-mediated oncogenic function of the menin tumor suppressor in breast cancer KMA Dreijerink, AC Groner, ESM Vos, A Font-Tello, L Gu, D Chi, J Reyes, ... Cell reports 18 (10), 2359-2372, 2017 | 79 | 2017 |
| Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain MT Buckley, ED Sun, BM George, L Liu, N Schaum, L Xu, JM Reyes, ... Nature Aging 3 (1), 121-137, 2023 | 74 | 2023 |
| BET bromodomain proteins regulate enhancer function during adipogenesis JD Brown, ZB Feldman, SP Doherty, JM Reyes, PB Rahl, CY Lin, ... Proceedings of the National Academy of Sciences 115 (9), 2144-2149, 2018 | 74 | 2018 |
| Trisomy of a Down syndrome critical region globally amplifies transcription via HMGN1 overexpression CT Mowery, JM Reyes, L Cabal-Hierro, KJ Higby, KL Karlin, JH Wang, ... Cell reports 25 (7), 1898-1911. e5, 2018 | 59 | 2018 |
| Deregulation of the Ras-Erk signaling axis modulates the enhancer landscape B Nabet, PÓ Broin, JM Reyes, K Shieh, CY Lin, CM Will, R Popovic, ... Cell reports 12 (8), 1300-1313, 2015 | 50 | 2015 |
| Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor YH Huang, CW Chen, V Sundaramurthy, M Słabicki, D Hao, CJ Watson, ... Cancer discovery 12 (1), 220-235, 2022 | 42 | 2022 |
| Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging L Liu, S Kim, MT Buckley, JM Reyes, J Kang, L Tian, M Wang, A Lieu, ... Cell stem cell 30 (5), 689-705. e4, 2023 | 29 | 2023 |
| Tissue-biased expansion of DNMT3A-mutant clones in a mosaic individual is associated with conserved epigenetic erosion A Tovy, JM Reyes, MC Gundry, L Brunetti, H Lee-Six, M Petljak, HJ Park, ... Cell Stem Cell 27 (2), 326-335. e4, 2020 | 29 | 2020 |
| Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome A Tovy, C Rosas, AS Gaikwad, G Medrano, L Zhang, JM Reyes, ... Haematologica, 2021 | 21 | 2021 |
Margaret GoodellBaylor College of MedicineVerified email at bcm.edu
