Patrick Guye
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A bipartite signal mediates the transfer of type IV secretion substrates of Bartonella henselae into human cells
R Schulein, P Guye, TA Rhomberg, MC Schmid, G Schröder, AC Vergunst, ...
Proceedings of the National Academy of Sciences 102 (3), 856-861, 2005
Rapid neurogenesis through transcriptional activation in human stem cells
V Busskamp, NE Lewis, P Guye, AHM Ng, SL Shipman, SM Byrne, ...
Molecular systems biology 10 (11), 760, 2014
Host cell interactome of tyrosine-phosphorylated bacterial proteins
M Selbach, FE Paul, S Brandt, P Guye, O Daumke, S Backert, C Dehio, ...
Cell host & microbe 5 (4), 397-403, 2009
Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
P Guye, MR Ebrahimkhani, N Kipniss, JJ Velazquez, E Schoenfeld, ...
Nature communications 7 (1), 10243, 2016
A platform for rapid prototyping of synthetic gene networks in mammalian cells
X Duportet, L Wroblewska, P Guye, Y Li, J Eyquem, J Rieders, T Rimchala, ...
Nucleic acids research 42 (21), 13440-13451, 2014
A translocated bacterial protein protects vascular endothelial cells from apoptosis
MC Schmid, F Scheidegger, M Dehio, N Balmelle-Devaux, R Schulein, ...
PLoS pathogens 2 (11), e115, 2006
Rapid, modular and reliable construction of complex mammalian gene circuits
P Guye, Y Li, L Wroblewska, X Duportet, R Weiss
Nucleic acids research 41 (16), e156-e156, 2013
Synthetic morphogenesis
BP Teague, P Guye, R Weiss
Cold Spring Harbor perspectives in biology 8 (9), a023929, 2016
A translocated protein of Bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the …
TA Rhomberg, MC Truttmann, P Guye, Y Ellner, C Dehio
Cellular microbiology 11 (6), 927-945, 2009
Comparing in vitro human liver models to in vivo human liver using RNA-Seq
R Gupta, Y Schrooders, D Hauser, M van Herwijnen, W Albrecht, ...
Archives of toxicology 95, 573-589, 2021
Fic domain‐catalyzed adenylylation: insight provided by the structural analysis of the type IV secretion system effector BepA
DV Palanivelu, A Goepfert, M Meury, P Guye, C Dehio, T Schirmer
Protein science 20 (3), 492-499, 2011
Distinct activities of Bartonella henselae type IV secretion effector proteins modulate capillary‐like sprout formation
F Scheidegger, Y Ellner, P Guye, TA Rhomberg, H Weber, HG Augustin, ...
Cellular microbiology 11 (7), 1088-1101, 2009
Preserved DNA damage checkpoint pathway protects against complications in long-standing type 1 diabetes
S Bhatt, MK Gupta, M Khamaisi, R Martinez, MA Gritsenko, BK Wagner, ...
Cell metabolism 22 (2), 239-252, 2015
Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells
W Li, S Lee, M Ma, SM Kim, P Guye, JR Pancoast, DG Anderson, R Weiss, ...
Scientific reports 3 (1), 2863, 2013
A Translocated Effector Required for Bartonella Dissemination from Derma to Blood Safeguards Migratory Host Cells from Damage by Co-translocated Effectors
R Okujava, P Guye, YY Lu, C Mistl, F Polus, M Vayssier-Taussat, C Halin, ...
PLoS pathogens 10 (6), e1004187, 2014
Network integration and modelling of dynamic drug responses at multi-omics levels
N Selevsek, F Caiment, R Nudischer, H Gmuender, I Agarkova, ...
Communications biology 3 (1), 573, 2020
Design and connection of robust genetic circuits
A Randall, P Guye, S Gupta, X Duportet, R Weiss
Methods in enzymology 497, 159-186, 2011
BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures
MC Truttmann, P Guye, C Dehio
PLoS One 6 (10), e25106, 2011
A 3D heterotypic multicellular tumor spheroid assay platform to discriminate drug effects on stroma versus cancer cells
Z Weydert, M Lal-Nag, L Mathews-Greiner, C Thiel, H Cordes, L Küpfer, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (3), 265-276, 2020
Engineering a heterogeneous tissue from pluripotent stem cells
P Guye, R Weiss, MR Ebrahimkhani
US Patent 9,677,085, 2017
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