| Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence G Hewitt, D Jurk, FDM Marques, C Correia-Melo, T Hardy, A Gackowska, ... Nature communications 3 (1), 1-9, 2012 | 872 | 2012 |
| Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5, 4172, 2014 | 762 | 2014 |
| Mitochondria are required for pro‐ageing features of the senescent phenotype C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ... The EMBO journal, e201592862, 2016 | 620 | 2016 |
| Lysosome-mediated processing of chromatin in senescence A Ivanov, J Pawlikowski, I Manoharan, J van Tuyn, DM Nelson, TS Rai, ... J Cell Biol, jcb. 201212110, 2013 | 511 | 2013 |
| Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers CF Houlihan, N Vora, T Byrne, D Lewer, G Kelly, J Heaney, S Gandhi, ... The Lancet 396 (10246), e6-e7, 2020 | 247 | 2020 |
| Mechanism and regulation of DNA-Protein crosslink repair by the DNA-dependent metalloprotease SPRTN J Stingele, R Bellelli, F Alte, G Hewitt, G Sarek, SL Maslen, SE Tsutakawa, ... Molecular Cell 64 (4), 688-703, 2016 | 237 | 2016 |
| Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence? C Correia-Melo, G Hewitt, JF Passos Longevity & healthspan 3 (1), 1, 2014 | 190 | 2014 |
| Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance D Zatreanu, HMR Robinson, O Alkhatib, M Boursier, H Finch, L Geo, ... Nature Communications 12 (1), 1-15, 2021 | 187 | 2021 |
| DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease J Birch, RK Anderson, C Correia-Melo, D Jurk, G Hewitt, FM Marques, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015 | 160 | 2015 |
| SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair G Hewitt, B Carroll, R Sarallah, C Correia-Melo, M Ogrodnik, G Nelson, ... Autophagy 12 (10), 1917-1930, 2016 | 145 | 2016 |
| Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections J Hellewell, TW Russell, R Beale, G Kelly, C Houlihan, E Nastouli, ... BMC medicine 19 (1), 1-10, 2021 | 141 | 2021 |
| Repair, Reuse, Recycle: The Expanding Role of Autophagy in Genome Maintenance G Hewitt, VI Korolchuk Trends in Cell Biology, 2016 | 139 | 2016 |
| Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2 L Au, A Fendler, STC Shepherd, K Rzeniewicz, M Cerrone, F Byrne, ... Nature Medicine, 1-5, 2021 | 83 | 2021 |
| Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD G Hewitt, V Borel, S Segura-Bayona, T Takaki, P Ruis, R Bellelli, ... Molecular Cell, 2020 | 82 | 2020 |
| SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance S Panier, M Maric, G Hewitt, E Mason-Osann, H Gali, A Dai, A Labadorf, ... Molecular Cell, 2019 | 77 | 2019 |
| Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors K Fugger, I Bajrami, MS Dos Santos, SJ Young, S Kunzelmann, G Kelly, ... Science 372 (6538), 156-165, 2021 | 74 | 2021 |
| Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1 LC Lehmann, G Hewitt, S Aibara, A Leitner, E Marklund, SL Maslen, ... Molecular Cell 68 (5), 847-859. e7, 2017 | 60 | 2017 |
| Autophagy and ageing: implications for age-related neurodegenerative diseases B Carroll, G Hewitt, VI Korolchuk Essays in biochemistry 55, 119-131, 2013 | 60 | 2013 |
| mTORC1 activity is supported by spatial association with focal adhesions Y Rabanal-Ruiz, A Byron, A Wirth, R Madsen, L Sedlackova, G Hewitt, ... Journal of Cell Biology 220 (5), 2021 | 51 | 2021 |
| RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions P Kotsantis, S Segura-Bayona, P Margalef, P Marzec, P Ruis, G Hewitt, ... Cell Reports 33 (12), 108546, 2020 | 44 | 2020 |
Joao PassosProfessor, Mayo Clinic, MN, USAVerified email at mayo.edu
