Regulation of the specific DNA binding function of p53 TR Hupp, DW Meek, CA Midgley, DP Lane Cell 71 (5), 875-886, 1992 | 1303 | 1992 |
Tumour suppression by p53: a role for the DNA damage response? DW Meek Nature Reviews Cancer 9 (10), 714-723, 2009 | 772 | 2009 |
Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2 N Dumaz, DW Meek The EMBO journal 18 (24), 7002-7010, 1999 | 617 | 1999 |
Posttranslational modification of p53: cooperative integrators of function DW Meek, CW Anderson Cold Spring Harbor perspectives in biology 1 (6), a000950, 2009 | 553 | 2009 |
Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation S Kurki, K Peltonen, L Latonen, TM Kiviharju, PM Ojala, D Meek, M Laiho Cancer cell 5 (5), 465-475, 2004 | 525 | 2004 |
The p53 response to DNA damage DW Meek DNA repair 3 (8-9), 1049-1056, 2004 | 503 | 2004 |
The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II. DW Meek, S Simon, U Kikkawa, W Eckhart The EMBO journal 9 (10), 3253-3260, 1990 | 374 | 1990 |
Regulation of the p53 response and its relationship to cancer DW Meek Biochemical Journal 469 (3), 325-346, 2015 | 364 | 2015 |
Mechanisms of switching on p53: a role for covalent modification? DW Meek Oncogene 18 (53), 7666-7675, 1999 | 360 | 1999 |
p53 Is Phosphorylated in Vitro and in Vivo by an Ultraviolet Radiation-induced Protein Kinase Characteristic of the c-Jun Kinase, JNK1 (∗) DM Milne, LE Campbell, DG Campbell, DW Meek Journal of Biological Chemistry 270 (10), 5511-5518, 1995 | 351 | 1995 |
Posttranslational modification of MDM2 DW Meek, U Knippschild Molecular cancer research 1 (14), 1017-1026, 2003 | 320 | 2003 |
p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-κB subunit with histone deacetylase 1 S Rocha, AM Martin, DW Meek, ND Perkins Molecular and cellular biology 23 (13), 4713-4727, 2003 | 311 | 2003 |
Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters J Loughery, M Cox, LM Smith, DW Meek Nucleic acids research 42 (12), 7666-7680, 2014 | 307 | 2014 |
Activation of the cryptic DNA binding function of mutant forms of p53 TR Hupp, DW Meek, CA Midgley, DP Lane Nucleic acids research 21 (14), 3167-3174, 1993 | 265 | 1993 |
Multisite phosphorylation and the integration of stress signals at p53 DW Meek Cellular signalling 10 (3), 159-166, 1998 | 256 | 1998 |
p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase … U Knippschild, DM Milne, LE Campbell, AJ DeMaggio, E Christenson, ... Oncogene 15 (14), 1727-1736, 1997 | 243 | 1997 |
Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases. DM Milne, DG Campbell, FB Caudwell, DW Meek Journal of Biological Chemistry 269 (12), 9253-9260, 1994 | 241 | 1994 |
Post-translational modification of p53. DW Meek Seminars in cancer biology 5 (3), 203-210, 1994 | 228 | 1994 |
Phosphorylation of the p53 tumour-suppressor protein at three N-terminal sites by a novel casein kinase I-like enzyme. DM Milne, RH Palmer, DG Campbell, DW Meek Oncogene 7 (7), 1361-1369, 1992 | 215 | 1992 |
Protein kinase CK1 is a p53‐threonine 18 kinase which requires prior phosphorylation of serine 15 N Dumaz, DM Milne, DW Meek FEBS letters 463 (3), 312-316, 1999 | 209 | 1999 |