| Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands PI Kitov, JM Sadowska, G Mulvey, GD Armstrong, H Ling, NS Pannu, ... Nature 403 (6770), 669-672, 2000 | 1120 | 2000 |
| On the nature of the multivalency effect: a thermodynamic model PI Kitov, DR Bundle Journal of the American Chemical Society 125 (52), 16271-16284, 2003 | 583 | 2003 |
| Assessment in mice of the therapeutic potential of tailored, multivalent Shiga toxin carbohydrate ligands GL Mulvey, P Marcato, PI Kitov, J Sadowska, DR Bundle, GD Armstrong The Journal of infectious diseases 187 (4), 640-649, 2003 | 197 | 2003 |
| Optimization of Tether Length in Nonglycosidically Linked Bivalent Ligands That Target Sites 2 and 1 of a Shiga-like Toxin PI Kitov, H Shimizu, SW Homans, DR Bundle Journal of the American Chemical Society 125 (11), 3284-3294, 2003 | 144 | 2003 |
| A mutational analysis of the globotriaosylceramide-binding sites of verotoxin VT1 AM Soltyk, CR MacKenzie, VM Wolski, T Hirama, PI Kitov, DR Bundle, ... Journal of Biological Chemistry 277 (7), 5351-5359, 2002 | 125 | 2002 |
| Rapid biocompatible macrocyclization of peptides with decafluoro-diphenylsulfone S Kalhor-Monfared, MR Jafari, JT Patterson, PI Kitov, JJ Dwyer, JM Nuss, ... Chemical science 7 (6), 3785-3790, 2016 | 100 | 2016 |
| In vivo supramolecular templating enhances the activity of multivalent ligands: a potential therapeutic against the Escherichia coli O157 AB5 toxins PI Kitov, GL Mulvey, TP Griener, T Lipinski, D Solomon, E Paszkiewicz, ... Proceedings of the National Academy of Sciences 105 (44), 16837-16842, 2008 | 100 | 2008 |
| Discovery of light-responsive ligands through screening of a light-responsive genetically encoded library MR Jafari, L Deng, PI Kitov, S Ng, WL Matochko, KF Tjhung, A Zeberoff, ... ACS chemical biology 9 (2), 443-450, 2014 | 89 | 2014 |
| Bifunctional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells MK O’Reilly, BE Collins, S Han, L Liao, C Rillahan, PI Kitov, DR Bundle, ... Journal of the American Chemical Society 130 (24), 7736-7745, 2008 | 84 | 2008 |
| Targeting norovirus infection—multivalent entry inhibitor design based on NMR experiments C Rademacher, J Guiard, PI Kitov, B Fiege, KP Dalton, F Parra, ... Chemistry–A European Journal 17 (27), 7442-7453, 2011 | 83 | 2011 |
| Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins S Ng, E Lin, PI Kitov, KF Tjhung, OO Gerlits, L Deng, B Kasper, A Sood, ... Journal of the American Chemical Society 137 (16), 5248-5251, 2015 | 80 | 2015 |
| Glycan mimicry as a basis for novel anti-infective drugs G Mulvey, PI Kitov, P Marcato, DR Bundle, GD Armstrong Biochimie 83 (8), 841-847, 2001 | 80 | 2001 |
| Rapid, hydrolytically stable modification of aldehyde-terminated proteins and phage libraries PI Kitov, DF Vinals, S Ng, KF Tjhung, R Derda Journal of the American Chemical Society 136 (23), 8149-8152, 2014 | 78 | 2014 |
| Molecular details of the recognition of blood group antigens by a human norovirus as determined by STD NMR spectroscopy B Fiege, C Rademacher, J Cartmell, PI Kitov, F Parra, T Peters Angewandte Chemie 124 (4), 952-956, 2012 | 76 | 2012 |
| The observation of multivalent complexes of Shiga-like toxin with globotriaoside and the determination of their stoichiometry by nanoelectrospray Fourier-transform ion … EN Kitova, PI Kitov, DR Bundle, JS Klassen Glycobiology 11 (7), 605-611, 2001 | 76 | 2001 |
| Affinities of Shiga toxins 1 and 2 for univalent and oligovalent Pk-trisaccharide analogs measured by electrospray ionization mass spectrometry EN Kitova, PI Kitov, E Paszkiewicz, J Kim, GL Mulvey, GD Armstrong, ... Glycobiology 17 (10), 1127-1137, 2007 | 65 | 2007 |
| Silent encoding of chemical post-translational modifications in phage-displayed libraries KF Tjhung, PI Kitov, S Ng, EN Kitova, L Deng, JS Klassen, R Derda Journal of the American Chemical Society 138 (1), 32-35, 2016 | 59 | 2016 |
| Surface plasmon resonance imaging measurements of the inhibition of Shiga-like toxin by synthetic multivalent inhibitors V Kanda, P Kitov, DR Bundle, MT McDermott Analytical chemistry 77 (23), 7497-7504, 2005 | 59 | 2005 |
| Multifunctional multivalency: a focused library of polymeric cholera toxin antagonists HA Tran, PI Kitov, E Paszkiewicz, JM Sadowska, DR Bundle Organic & Biomolecular Chemistry 9 (10), 3658-3671, 2011 | 55 | 2011 |
| A comparison of mineral affinity of bisphosphonate–protein conjugates constructed with disulfide and thioether linkages JEI Wright, SA Gittens, G Bansal, PI Kitov, D Sindrey, C Kucharski, ... Biomaterials 27 (5), 769-784, 2006 | 55 | 2006 |
Ratmir DerdaProfessor of Chemistry, University of AlbertaVerified email at ualberta.ca
