Small molecules targeting severe acute respiratory syndrome human coronavirus CY Wu, JT Jan, SH Ma, CJ Kuo, HF Juan, YSE Cheng, HH Hsu, ... Proceedings of the National Academy of Sciences 101 (27), 10012-10017, 2004 | 633 | 2004 |
Engineering the ABA plant stress pathway for regulation of induced proximity FS Liang, WQ Ho, GR Crabtree Science signaling 4 (164), rs2-rs2, 2011 | 257 | 2011 |
Dual Effect of Synthetic Aminoglycosides: Antibacterial Activity against Bacillus anthracis and Inhibition of Anthrax Lethal Factor M Fridman, V Belakhov, LV Lee, FS Liang, CH Wong, T Baasov Angewandte Chemie International Edition 44 (3), 447-452, 2005 | 92 | 2005 |
Dimeric aminoglycosides as antibiotics F Agnelli, SJ Sucheck, KA Marby, D Rabuka, SL Yao, PS Sears, FS Liang, ... Angewandte Chemie 116 (12), 1588-1592, 2004 | 82 | 2004 |
Reaction-based “off–on” fluorescent probe enabling detection of endogenous labile Fe2+ and imaging of Zn2+-induced Fe2+ flux in living cells and elevated Fe2+ in ischemic stroke W Xuan, R Pan, Y Wei, Y Cao, H Li, FS Liang, KJ Liu, W Wang Bioconjugate chemistry 27 (2), 302-308, 2016 | 70 | 2016 |
Chemically controlled epigenome editing through an inducible dCas9 system T Chen, D Gao, R Zhang, G Zeng, H Yan, E Lim, FS Liang Journal of the American Chemical Society 139 (33), 11337-11340, 2017 | 65 | 2017 |
Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides LV Lee, KE Bower, FS Liang, J Shi, D Wu, SJ Sucheck, PK Vogt, ... Journal of the american Chemical society 126 (15), 4774-4775, 2004 | 62 | 2004 |
Regulating miRNA-21 biogenesis by bifunctional small molecules H Yan, U Bhattarai, ZF Guo, FS Liang Journal of the American Chemical Society 139 (14), 4987-4990, 2017 | 55 | 2017 |
Light control of cellular processes by using photocaged abscisic acid CW Wright, ZF Guo, FS Liang ChemBioChem 16 (2), 254-261, 2015 | 53 | 2015 |
Investigating crosstalk between H3K27 acetylation and H3K4 trimethylation in CRISPR/dCas-based epigenome editing and gene activation W Zhao, Y Xu, Y Wang, D Gao, J King, Y Xu, FS Liang Scientific reports 11 (1), 15912, 2021 | 42 | 2021 |
Targeting RNAs with tobramycin analogues FS Liang, SK Wang, T Nakatani, CH Wong Angewandte Chemie International Edition 43 (47), 6496-6500, 2004 | 41 | 2004 |
Inducible and reversible RNA N6-methyladenosine editing H Shi, Y Xu, N Tian, M Yang, FS Liang Nature Communications 13 (1), 1958, 2022 | 28 | 2022 |
Cyclic peptidomimetics as inhibitor for miR-155 biogenesis H Yan, M Zhou, U Bhattarai, Y Song, M Zheng, J Cai, FS Liang Molecular pharmaceutics 16 (2), 914-920, 2019 | 22 | 2019 |
Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates FS Liang, A Brik, YC Lin, JH Elder, CH Wong Bioorganic & medicinal chemistry 14 (4), 1058-1062, 2006 | 22 | 2006 |
Constructing de Novo H2O2 Signaling via Induced Protein Proximity G Zeng, R Zhang, W Xuan, W Wang, FS Liang ACS chemical biology 10 (6), 1404-1410, 2015 | 19 | 2015 |
Engineering iron responses in mammalian cells by signal-induced protein proximity G Zeng, H Li, Y Wei, W Xuan, R Zhang, LE Breden, W Wang, FS Liang ACS synthetic biology 6 (6), 921-927, 2017 | 18 | 2017 |
Facile functionalization of FK506 for biological studies by the thiol–ene ‘click’reaction ZF Guo, R Zhang, FS Liang RSC Advances 4 (22), 11400-11403, 2014 | 17 | 2014 |
Surface plasmon resonance study of RNA–aminoglycoside interactions CH Wong, FS Liang Methods in enzymology 362, 340-353, 2003 | 17 | 2003 |
Chemical and light inducible epigenome editing W Zhao, Y Wang, FS Liang International Journal of Molecular Sciences 21 (3), 998, 2020 | 14 | 2020 |
miRNA inhibition by proximity-enabled Dicer inactivation H Yan, FS Liang Methods 167, 117-123, 2019 | 13 | 2019 |