Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling HL Fu, RR Valiathan, R Arkwright, A Sohail, C Mihai, M Kumarasiri, ... Journal of Biological Chemistry 288 (11), 7430-7437, 2013 | 234 | 2013 |
Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation L Alinari, KV Mahasenan, F Yan, V Karkhanis, JH Chung, EM Smith, ... Blood 125 (16), 2530-2543, 2015 | 164 | 2015 |
Carborane clusters in computational drug design: A comparative docking evaluation using AutoDock, FlexX, Glide, and Surflex R Tiwari, K Mahasenan, R Pavlovicz, C Li, W Tjarks Journal of chemical information and modeling 49 (6), 1581-1589, 2009 | 110 | 2009 |
Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 … TT Nguyen, D Ding, WR Wolter, RL Perez, MM Champion, ... Journal of Medicinal Chemistry, 2018 | 104 | 2018 |
Antitrypanosomal activity of 1, 2-dihydroquinolin-6-ols and their ester derivatives J Fotie, M Kaiser, DA Delfín, J Manley, CS Reid, JM Paris, T Wenzler, ... Journal of medicinal chemistry 53 (3), 966-982, 2010 | 98 | 2010 |
Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases HL Fu, A Sohail, RR Valiathan, BD Wasinski, M Kumarasiri, ... Journal of Biological Chemistry 288 (17), 12114-12129, 2013 | 92 | 2013 |
Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant Staphylococcus aureus, Allosteric Communication Network and Enablement of … KV Mahasenan, R Molina, R Bouley, MT Batuecas, JF Fisher, ... Journal of the American Chemical Society 139 (5), 2102-2110, 2017 | 91 | 2017 |
Cyclic peptide inhibitors of HIV-1 capsid-human lysyl-tRNA synthetase interaction V Dewan, T Liu, KM Chen, Z Qian, Y Xiao, L Kleiman, KV Mahasenan, ... ACS Chemical Biology 7 (4), 761-769, 2012 | 55 | 2012 |
Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase MltC of Escherichia coli C Artola-Recolons, M Lee, N Bernardo-García, B Blázquez, D Hesek, ... ACS chemical biology 9 (9), 2058-2066, 2014 | 52 | 2014 |
The quinazolinone allosteric inhibitor of PBP2a synergizes with piperacillin and tazobactam against methicillin-resistant Staphylococcus aureus J Janardhanan, R Bouley, S Martínez-Caballero, Z Peng, ... Antimicrobial agents and chemotherapy, AAC. 02637-18, 2019 | 48 | 2019 |
Three-dimensional QSAR analysis and design of new 1, 2, 4-oxadiazole antibacterials E Leemans, KV Mahasenan, M Kumarasiri, E Spink, D Ding, PI O’Daniel, ... Bioorganic & medicinal chemistry letters 26 (3), 1011-1015, 2016 | 48 | 2016 |
Synthesis, biological evaluation, and molecular modeling of 3, 5-substituted-N1-phenyl-N4, N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents TG George, MM Endeshaw, RE Morgan, KV Mahasenan, DA Delfín, ... Bioorganic & medicinal chemistry 15 (18), 6071, 2007 | 48 | 2007 |
O-Phenyl Carbamate and Phenyl Urea Thiiranes as Selective Matrix Metalloproteinase-2 Inhibitors that Cross the Blood–Brain Barrier M Gooyit, W Song, KV Mahasenan, K Lichtenwalter, MA Suckow, ... Journal of medicinal chemistry 56 (20), 8139-8150, 2013 | 40 | 2013 |
Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa M Lee, MT Batuecas, S Tomoshige, T Domínguez-Gil, KV Mahasenan, ... Proceedings of the National Academy of Sciences - USA, 2018 | 39 | 2018 |
Glycosylation at ASN211 regulates the activation state of the discoidin domain receptor 1 (DDR1) HL Fu, RR Valiathan, L Payne, M Kumarasiri, KV Mahasenan, ... Journal of Biological Chemistry 289 (13), 9275-9287, 2014 | 39 | 2014 |
Exploration of the Structural Space in 4(3H)-Quinazolinone Antibacterials Y Qian, G Allegretta, J Janardhanan, Z Peng, KV Mahasenan, ... Journal of Medicinal Chemistry, 2020 | 38 | 2020 |
Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division M Alcorlo, DA Dik, S De Benedetti, KV Mahasenan, M Lee, ... Nature Communications 10 (1), 1-13, 2019 | 34 | 2019 |
Mechanism of the Escherichia coli MltE lytic transglycosylase, the cell-wall-penetrating enzyme for Type VI secretion system assembly B Byun, KV Mahasenan, DA Dik, DR Marous, E Speri, M Kumarasiri, ... Scientific reports 8 (1), 4110, 2018 | 33 | 2018 |
Allostery, Recognition of Nascent Peptidoglycan, and Cross-linking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae N Bernardo-García, KV Mahasenan, MT Batuecas, M Lee, D Hesek, ... ACS Chemical Biology 13 (3), 694-702, 2018 | 33 | 2018 |
Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa T Domínguez-Gil, M Lee, I Acebrón-Avalos, KV Mahasenan, D Hesek, ... Structure 24 (10), 1729-1741, 2016 | 32 | 2016 |