Yumi Yashiro-Ohtani
Yumi Yashiro-Ohtani
Carisma Therapeutics
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c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
AP Weng, JM Millholland, Y Yashiro-Ohtani, ML Arcangeli, A Lau, C Wai, ...
Genes & development 20 (15), 2096-2109, 2006
Human chimeric antigen receptor macrophages for cancer immunotherapy
M Klichinsky, M Ruella, O Shestova, XM Lu, A Best, M Zeeman, ...
Nature biotechnology 38 (8), 947-953, 2020
Notch directly regulates Gata3 expression during T helper 2 cell differentiation
TC Fang, Y Yashiro-Ohtani, C Del Bianco, DM Knoblock, SC Blacklow, ...
Immunity 27 (1), 100-110, 2007
A critical role for TCF-1 in T-lineage specification and differentiation
BN Weber, AWS Chi, A Chavez, Y Yashiro-Ohtani, Q Yang, O Shestova, ...
Nature 476 (7358), 63-68, 2011
The requirement for Notch signaling at the β-selection checkpoint in vivo is absolute and independent of the pre–T cell receptor
I Maillard, LL Tu, A Sambandam, Y Yashiro-Ohtani, J Millholland, ...
The Journal of experimental medicine 203 (10), 2239-2245, 2006
Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1
BJ Wouters, MA Jorda, K Keeshan, I Louwers, ...
Blood, The Journal of the American Society of Hematology 110 (10), 3706-3714, 2007
Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts
Y Yashiro-Ohtani, XY Zhou, K Toyo-Oka, XG Tai, CS Park, T Hamaoka, ...
the Journal of Immunology 164 (3), 1251-1259, 2000
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
Y Yashiro-Ohtani, Y He, T Ohtani, ME Jones, O Shestova, L Xu, TC Fang, ...
Genes & development 23 (14), 1665-1676, 2009
The expression of Sox17 identifies and regulates haemogenic endothelium
RL Clarke, AD Yzaguirre, Y Yashiro-Ohtani, A Bondue, C Blanpain, ...
Nature cell biology 15 (5), 502-510, 2013
Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia
Y Yashiro-Ohtani, H Wang, C Zang, KL Arnett, W Bailis, Y Ho, B Knoechel, ...
Proceedings of the National Academy of Sciences 111 (46), E4946-E4953, 2014
Notch simultaneously orchestrates multiple helper T cell programs independently of cytokine signals
W Bailis, Y Yashiro-Ohtani, TC Fang, RD Hatton, CT Weaver, D Artis, ...
Immunity 39 (1), 148-159, 2013
The unique target specificity of a nonpeptide chemokine receptor antagonist: selective blockade of two Th1 chemokine receptors CCR5 and CXCR3
P Gao, XY Zhou, Y Yashiro-Ohtani, YF Yang, N Sugimoto, S Ono, ...
Journal of Leucocyte Biology 73 (2), 273-280, 2003
NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network
S Ohashi, M Natsuizaka, Y Yashiro–Ohtani, RA Kalman, M Nakagawa, ...
Gastroenterology 139 (6), 2113-2123, 2010
Active Notch1 confers a transformed phenotype to primary human melanocytes
CC Pinnix, JT Lee, ZJ Liu, R McDaid, K Balint, LJ Beverly, PA Brafford, ...
Cancer research 69 (13), 5312-5320, 2009
Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1
R Fragoso, T Mao, S Wang, S Schaffert, X Gong, S Yue, R Luong, H Min, ...
Public Library of Science 8 (8), e1002855, 2012
T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1
ME De Obaldia, JJ Bell, X Wang, C Harly, Y Yashiro-Ohtani, JH DeLong, ...
Nature immunology 14 (12), 1277-1284, 2013
A role for CD9 molecules in T cell activation.
XG Tai, Y Yashiro, R Abe, K Toyooka, CR Wood, J Morris, A Long, S Ono, ...
The Journal of experimental medicine 184 (2), 753-758, 1996
Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway
T Nakanishi, A Hayashi, J Kunisawa, Y Tsutsumi, K Tanaka, ...
European Journal of Immunology 30 (6), 1740-1747, 2000
Molecular mechanisms underlying differential contribution of CD28 versus non-CD28 costimulatory molecules to IL-2 promoter activation
XY Zhou, Y Yashiro-Ohtani, M Nakahira, WR Park, R Abe, T Hamaoka, ...
The Journal of Immunology 168 (8), 3847-3854, 2002
A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co‐stimulatory molecules
Y Yashiro, XG Tai, K Toyo‐oka, CS Park, R Abe, T Hamaoka, ...
European journal of immunology 28 (3), 926-935, 1998
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