Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60 Y Xiao, Y Nagai, G Deng, T Ohtani, Z Zhu, Z Zhou, H Zhang, MQ Ji, ... Cell reports 7 (5), 1471-1480, 2014 | 129 | 2014 |
Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function X Song, B Li, Y Xiao, C Chen, Q Wang, Y Liu, A Berezov, C Xu, Y Gao, ... Cell Reports, 2012 | 120 | 2012 |
Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function Y Xiao, B Li, Z Zhou, WW Hancock, H Zhang, MI Greene Current opinion in immunology 22 (5), 583-591, 2010 | 97 | 2010 |
Pim-2 kinase influences regulatory T cell function and stability by mediating Foxp3 protein N-terminal phosphorylation G Deng, Y Nagai, Y Xiao, Z Li, S Dai, T Ohtani, A Banham, B Li, SL Wu, ... Journal of Biological Chemistry 290 (33), 20211-20220, 2015 | 85 | 2015 |
PRMT5 Associates With the FOXP3 Homomer and When Disabled Enhances Targeted p185erbB2/neu Tumor Immunotherapy Y Nagai, MQ Ji, F Zhu, Y Xiao, Y Tanaka, T Kambayashi, S Fujimoto, ... Frontiers in immunology 10, 174, 2019 | 69 | 2019 |
Suppression by human FOXP3+ regulatory T cells requires FOXP3-TIP60 interactions K Bin Dhuban, E d’Hennezel, Y Nagai, Y Xiao, S Shao, R Istomine, ... Science immunology 2 (12), eaai9297, 2017 | 56 | 2017 |
Immune regulation by histone deacetylases: a focus on the alteration of FOXP3 activity H Zhang, Y Xiao, Z Zhu, B Li, MI Greene Immunology and cell biology 90 (1), 95-100, 2012 | 49 | 2012 |
Lysosome-dependent p300/FOXP3 degradation and limits Treg cell functions and enhances targeted therapy against cancers T Du, Y Nagai, Y Xiao, MI Greene, H Zhang Experimental and molecular pathology 95 (1), 38-45, 2013 | 42 | 2013 |
Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells G Deng, Y Xiao, Z Zhou, Y Nagai, H Zhang, B Li, MI Greene Experimental and molecular pathology 93 (3), 334-338, 2012 | 32 | 2012 |
IHF-binding sites inhibit DNA loop formation and transcription initiation YX Huo, YT Zhang, Y Xiao, X Zhang, M Buck, A Kolb, YP Wang Nucleic acids research 37 (12), 3878-3886, 2009 | 30 | 2009 |
Construction and functional analyses of a comprehensive σ54 site-directed mutant library using alanine–cysteine mutagenesis Y Xiao, SR Wigneshweraraj, R Weinzierl, YP Wang, M Buck Nucleic acids research 37 (13), 4482-4497, 2009 | 12 | 2009 |
Therapy of autoimmune colitis using a TIP60 inhibitor MI Greene, WW Hancock, M Katsumata, Y Xiao US Patent 8,497,285, 2013 | 7 | 2013 |
Complementation analyses of Sinorhizobium meliloti nifA mutant with different originated nifA genes Z Yao, Z Tian, X Dai, A Becker, J Li, H Yan, Y Xiao, J Zhu, G Yu, S Rüverg, ... Chinese Science Bulletin 51, 2748-2754, 2006 | 4 | 2006 |
TIP60 inhibitors MI Greene, A Berezov, Y Xiao, H Zhang US Patent 9,701,631, 2017 | | 2017 |
PRMT5 is a novel cofactor of Foxp3 and can be a target for tumor immunotherapy Y Nagai, M Ji, Y Xiao, H Zhang, B Li, T Ohtani, MI Greene The Journal of Immunology 196 (1_Supplement), 211.7-211.7, 2016 | | 2016 |