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F. Brad Johnson, MD, PhD
F. Brad Johnson, MD, PhD
Professor of Pathology and Laboratory Medicine
Verified email at pennmedicine.upenn.edu
Title
Cited by
Cited by
Year
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia
JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ...
Nature medicine 24 (5), 563-571, 2018
13652018
Histone H4 lysine 16 acetylation regulates cellular lifespan
W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson, A Shilatifard, ...
Nature 459 (7248), 802-807, 2009
7312009
Molecular biology of aging
FB Johnson, DA Sinclair, L Guarente
Cell 96 (2), 291-302, 1999
7101999
Astrocyte senescence as a component of Alzheimer’s disease
R Bhat, EP Crowe, A Bitto, M Moh, CD Katsetos, FU Garcia, FB Johnson, ...
Public Library of Science 7 (9), e45069, 2012
5472012
Detection of G-quadruplex DNA in mammalian cells
A Henderson, Y Wu, YC Huang, EA Chavez, J Platt, FB Johnson, ...
Nucleic acids research 42 (2), 860-869, 2013
4932013
Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae
SG Hershman, Q Chen, JY Lee, ML Kozak, P Yue, LS Wang, FB Johnson
Nucleic acids research 36 (1), 144-156, 2008
3372008
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
FB Johnson, RA Marciniak, M McVey, SA Stewart, WC Hahn, L Guarente
The EMBO journal 20 (4), 905-913, 2001
3322001
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells
MJ Frigault, J Lee, MC Basil, C Carpenito, S Motohashi, J Scholler, ...
Cancer immunology research 3 (4), 356-367, 2015
3122015
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
R Nativio, G Donahue, A Berson, Y Lan, A Amlie-Wolf, F Tuzer, JB Toledo, ...
Nature neuroscience 21 (4), 497-505, 2018
2852018
Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes
X Du, J Shen, N Kugan, EE Furth, DB Lombard, C Cheung, S Pak, G Luo, ...
Molecular and cellular biology 24 (19), 8437-8446, 2004
2572004
DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function
Q Yu, YV Katlinskaya, CJ Carbone, B Zhao, KV Katlinski, H Zheng, ...
Cell reports 11 (5), 785-797, 2015
2432015
Nucleolar localization of the Werner syndrome protein in human cells
RA Marciniak, DB Lombard, FB Johnson, L Guarente
Proceedings of the National Academy of Sciences 95 (12), 6887-6892, 1998
2401998
SLC25A51 is a mammalian mitochondrial NAD+ transporter
TS Luongo, JM Eller, MJ Lu, M Niere, F Raith, C Perry, MR Bornstein, ...
Nature 588 (7836), 174-179, 2020
2022020
Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging
S Imai, FB Johnson, RA Marciniak, M McVey, PU Park, L Guarente
Cold Spring Harbor symposia on quantitative biology 65, 297-302, 2000
1992000
Role for G-quadruplex RNA binding by Epstein-Barr virus nuclear antigen 1 in DNA replication and metaphase chromosome attachment
J Norseen, FB Johnson, PM Lieberman
Journal of virology 83 (20), 10336-10346, 2009
1902009
Association of the Bloom syndrome protein with topoisomerase IIIα in somatic and meiotic cells
FB Johnson, DB Lombard, NF Neff, MA Mastrangelo, W Dewolf, NA Ellis, ...
Cancer research 60 (5), 1162-1167, 2000
1872000
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential
JE Johnson, K Cao, P Ryvkin, LS Wang, FB Johnson
Nucleic acids research 38 (4), 1114-1122, 2010
1652010
Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis
RJ Pignolo, RK Suda, EA McMillan, J Shen, SH Lee, Y Choi, AC Wright, ...
Aging cell 7 (1), 23-31, 2008
1572008
Rudimentary G-quadruplex–based telomere capping in Saccharomyces cerevisiae
JS Smith, Q Chen, LA Yatsunyk, JM Nicoludis, MS Garcia, R Kranaster, ...
Nature structural & molecular biology 18 (4), 478-485, 2011
1562011
HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci
KM Aird, O Iwasaki, AV Kossenkov, H Tanizawa, N Fatkhutdinov, BG Bitler, ...
Journal of Cell Biology 215 (3), 325-334, 2016
1532016
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