A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels Science 363 (6429), 875-880, 2019 | 119 | 2019 |
Strategy for the synthesis of pyridazine heterocycles and their derivatives H Bel Abed, O Mammoliti, O Bande, G Van Lommen, P Herdewijn The Journal Of Organic Chemistry 78 (16), 7845-7858, 2013 | 69 | 2013 |
Organophosphorus-catalyzed diaza-Wittig reaction: Application to the synthesis of pyridazines HB Abed, O Mammoliti, O Bande, G Van Lommen, P Herdewijn Organic & Biomolecular Chemistry 12 (36), 7159-7166, 2014 | 42 | 2014 |
A General One‐Pot Synthesis of 2H‐Indazoles Using an Organophosphorus–Silane System J Schoene, H Bel Abed, P Schmieder, M Christmann, M Nazaré Chemistry–A European Journal 24 (36), 9090-9100, 2018 | 36 | 2018 |
Transition-Metal-Free Synthesis of Borylated Thiophenes via Formal Thioboration H Bel Abed, SA Blum Organic Letters 20 (21), 6673–6677, 2018 | 27 | 2018 |
Simple approach to the synthesis of 3-fluoro pyrazolo[1,5-a]pyrimidine analogues HB Abed, O Mammoliti, G Van Lommen, P Herdewijn Tetrahedron Letters 54 (21), 2612-2614, 2013 | 25 | 2013 |
A short and convenient strategy for the synthesis of pyridazines via Diaza–Wittig reaction HB Abed, O Mammoliti, G Van Lommen, P Herdewijn Tetrahedron Letters 53 (48), 6489-6491, 2012 | 25 | 2012 |
Organophosphorus-mediated N–N bond formation: facile access to 3-amino-2 H-indazoles HB Abed, J Schoene, M Christmann, M Nazaré Organic & Biomolecular Chemistry 14 (36), 8520-8528, 2016 | 19 | 2016 |
Novel strategy for the preparation of 3-perfluoroalkylated-2H-indazole derivatives HB Abed, N Weißing, J Schoene, J Paulus, N Sewald, M Nazaré Tetrahedron letters 59 (19), 1813-1815, 2018 | 16 | 2018 |
A straightforward approach to N-substituted-2H-indazol-2-amines through reductive cyclization J Schoene, HB Abed, M Christmann, M Nazaré Tetrahedron letters 58 (16), 1633-1635, 2017 | 16 | 2017 |
A novel and convenient strategy for the synthesis of phthalazines from an aryne precursor HB Abed, O Bande, O Mammoliti, G Van Lommen, P Herdewijn Tetrahedron Letters 54 (51), 7056-7058, 2013 | 14 | 2013 |
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α WT Lo, H Belabed, M Kücükdisli, J Metag, Y Roske, P Prokofeva, ... Nature chemical biology 19 (1), 18-27, 2023 | 12 | 2023 |
Phosphoinositide conversion inactivates R‐RAS and drives metastases in breast cancer H Li, L Prever, MY Hsu, WT Lo, JP Margaria, MC De Santis, C Zanini, ... Advanced Science 9 (9), 2103249, 2022 | 12 | 2022 |
Simple approach to the synthesis of novel tricyclic BACE1 inhibitor warhead through β-lactam opening HB Abed, SFA Van Brandt, JA Vega, HJM Gijsen Tetrahedron letters 56 (26), 4028-4030, 2015 | 10 | 2015 |
Antagonistic control of active surface integrins by myotubularin and phosphatidylinositol 3-kinase C2β in a myotubular myopathy model P Samsó, PA Koch, Y Posor, WT Lo, H Belabed, M Nazare, J Laporte, ... Proceedings of the National Academy of Sciences 119 (40), e2202236119, 2022 | 6 | 2022 |
Advancing ASMS with LC‐MS/MS for the discovery of novel PDCL2 ligands from DNA‐encoded chemical library selections Q Ye, H Belabed, Y Wang, Z Yu, M Palaniappan, JY Li, SA Kalovidouris, ... Andrology 11 (5), 808-815, 2023 | 4 | 2023 |
An LPAR5-antagonist that reduces nociception and increases pruriception J Langedijk, EI Araya, AR Barroso, D Tolenaars, M Nazaré, H Belabed, ... Frontiers in Pain Research 3, 963174, 2022 | 2 | 2022 |
LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF M REILLY, P FATHEREE, M FREIDBERG, H BELABED, G BRANDT WO Patent WO/2023/225,664, 2023 | | 2023 |
Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition M Kücükdisli, H Bel-Abed, D Cirillo, WT Lo, NL Efrém, A Horatscheck, ... Journal of Medicinal Chemistry 66 (20), 14278-14302, 2023 | | 2023 |
HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS WT LO, H BELABED, V HAUCKE, M NAZARE, M KÜCÜKDISLI WO Patent WO/2019/234,237, 2019 | | 2019 |