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Hassen Bel Abed
Hassen Bel Abed
Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)
Verified email at bcm.edu
Title
Cited by
Cited by
Year
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels
Science 363 (6429), 875-880, 2019
1192019
Strategy for the synthesis of pyridazine heterocycles and their derivatives
H Bel Abed, O Mammoliti, O Bande, G Van Lommen, P Herdewijn
The Journal Of Organic Chemistry 78 (16), 7845-7858, 2013
692013
Organophosphorus-catalyzed diaza-Wittig reaction: Application to the synthesis of pyridazines
HB Abed, O Mammoliti, O Bande, G Van Lommen, P Herdewijn
Organic & Biomolecular Chemistry 12 (36), 7159-7166, 2014
422014
A General One‐Pot Synthesis of 2H‐Indazoles Using an Organophosphorus–Silane System
J Schoene, H Bel Abed, P Schmieder, M Christmann, M Nazaré
Chemistry–A European Journal 24 (36), 9090-9100, 2018
362018
Transition-Metal-Free Synthesis of Borylated Thiophenes via Formal Thioboration
H Bel Abed, SA Blum
Organic Letters 20 (21), 6673–6677, 2018
272018
Simple approach to the synthesis of 3-fluoro pyrazolo[1,5-a]pyrimidine analogues
HB Abed, O Mammoliti, G Van Lommen, P Herdewijn
Tetrahedron Letters 54 (21), 2612-2614, 2013
252013
A short and convenient strategy for the synthesis of pyridazines via Diaza–Wittig reaction
HB Abed, O Mammoliti, G Van Lommen, P Herdewijn
Tetrahedron Letters 53 (48), 6489-6491, 2012
252012
Organophosphorus-mediated N–N bond formation: facile access to 3-amino-2 H-indazoles
HB Abed, J Schoene, M Christmann, M Nazaré
Organic & Biomolecular Chemistry 14 (36), 8520-8528, 2016
192016
Novel strategy for the preparation of 3-perfluoroalkylated-2H-indazole derivatives
HB Abed, N Weißing, J Schoene, J Paulus, N Sewald, M Nazaré
Tetrahedron letters 59 (19), 1813-1815, 2018
162018
A straightforward approach to N-substituted-2H-indazol-2-amines through reductive cyclization
J Schoene, HB Abed, M Christmann, M Nazaré
Tetrahedron letters 58 (16), 1633-1635, 2017
162017
A novel and convenient strategy for the synthesis of phthalazines from an aryne precursor
HB Abed, O Bande, O Mammoliti, G Van Lommen, P Herdewijn
Tetrahedron Letters 54 (51), 7056-7058, 2013
142013
Development of selective inhibitors of phosphatidylinositol 3-kinase C2α
WT Lo, H Belabed, M Kücükdisli, J Metag, Y Roske, P Prokofeva, ...
Nature chemical biology 19 (1), 18-27, 2023
122023
Phosphoinositide conversion inactivates R‐RAS and drives metastases in breast cancer
H Li, L Prever, MY Hsu, WT Lo, JP Margaria, MC De Santis, C Zanini, ...
Advanced Science 9 (9), 2103249, 2022
122022
Simple approach to the synthesis of novel tricyclic BACE1 inhibitor warhead through β-lactam opening
HB Abed, SFA Van Brandt, JA Vega, HJM Gijsen
Tetrahedron letters 56 (26), 4028-4030, 2015
102015
Antagonistic control of active surface integrins by myotubularin and phosphatidylinositol 3-kinase C2β in a myotubular myopathy model
P Samsó, PA Koch, Y Posor, WT Lo, H Belabed, M Nazare, J Laporte, ...
Proceedings of the National Academy of Sciences 119 (40), e2202236119, 2022
62022
Advancing ASMS with LC‐MS/MS for the discovery of novel PDCL2 ligands from DNA‐encoded chemical library selections
Q Ye, H Belabed, Y Wang, Z Yu, M Palaniappan, JY Li, SA Kalovidouris, ...
Andrology 11 (5), 808-815, 2023
42023
An LPAR5-antagonist that reduces nociception and increases pruriception
J Langedijk, EI Araya, AR Barroso, D Tolenaars, M Nazaré, H Belabed, ...
Frontiers in Pain Research 3, 963174, 2022
22022
LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF
M REILLY, P FATHEREE, M FREIDBERG, H BELABED, G BRANDT
WO Patent WO/2023/225,664, 2023
2023
Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition
M Kücükdisli, H Bel-Abed, D Cirillo, WT Lo, NL Efrém, A Horatscheck, ...
Journal of Medicinal Chemistry 66 (20), 14278-14302, 2023
2023
HETEROCYCLIC COMPOUNDS AS CLASS II PHOSPHOINOSITIDE 3-KINASE INHIBITORS
WT LO, H BELABED, V HAUCKE, M NAZARE, M KÜCÜKDISLI
WO Patent WO/2019/234,237, 2019
2019
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