The evolution of lung cancer and impact of subclonal selection in TRACERx AM Frankell, M Dietzen, M Al Bakir, EL Lim, T Karasaki, S Ward, ... Nature 616 (7957), 525-533, 2023 | 146 | 2023 |
Characterizing allele-and haplotype-specific copy numbers in single cells with CHISEL S Zaccaria, BJ Raphael Nature biotechnology 39 (2), 207-214, 2021 | 137 | 2021 |
Antibodies against endogenous retroviruses promote lung cancer immunotherapy KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ... Nature 616 (7957), 563-573, 2023 | 132 | 2023 |
Accurate quantification of copy-number aberrations and whole-genome duplications in multi-sample tumor sequencing data S Zaccaria, BJ Raphael Nature communications 11 (1), 4301, 2020 | 102 | 2020 |
The evolution of non-small cell lung cancer metastases in TRACERx M Al Bakir, A Huebner, C Martínez-Ruiz, K Grigoriadis, TBK Watkins, ... Nature 616 (7957), 534-542, 2023 | 94 | 2023 |
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment H Sun, S Cao, RJ Mashl, CK Mo, S Zaccaria, MC Wendl, SR Davies, ... Nature communications 12 (1), 5086, 2021 | 85 | 2021 |
SCARLET: single-cell tumor phylogeny inference with copy-number constrained mutation losses G Satas, S Zaccaria, G Mon, BJ Raphael Cell systems 10 (4), 323-332. e8, 2020 | 73 | 2020 |
The translational challenges of precision oncology O Pich, C Bailey, TBK Watkins, S Zaccaria, M Jamal-Hanjani, C Swanton Cancer Cell 40 (5), 458-478, 2022 | 66 | 2022 |
HapCol: accurate and memory-efficient haplotype assembly from long reads Y Pirola, S Zaccaria, R Dondi, GW Klau, N Pisanti, P Bonizzoni Bioinformatics 32 (11), 1610-1617, 2016 | 58 | 2016 |
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx T Karasaki, DA Moore, S Veeriah, C Naceur-Lombardelli, A Toncheva, ... Nature medicine 29 (4), 833-845, 2023 | 47 | 2023 |
On the minimum error correction problem for haplotype assembly in diploid and polyploid genomes P Bonizzoni, R Dondi, GW Klau, Y Pirola, N Pisanti, S Zaccaria Journal of Computational Biology 23 (9), 718-736, 2016 | 40 | 2016 |
Complexity and algorithms for copy-number evolution problems M El-Kebir, BJ Raphael, R Shamir, R Sharan, S Zaccaria, M Zehavi, ... Algorithms for Molecular Biology 12, 1-11, 2017 | 39 | 2017 |
Phylogenetic copy-number factorization of multiple tumor samples S Zaccaria, M El-Kebir, GW Klau, BJ Raphael Journal of Computational Biology 25 (7), 689-708, 2018 | 33 | 2018 |
Copy-number evolution problems: complexity and algorithms M El-Kebir, BJ Raphael, R Shamir, R Sharan, S Zaccaria, M Zehavi, ... International Workshop on Algorithms in Bioinformatics, 137-149, 2016 | 28 | 2016 |
DeCiFering the elusive cancer cell fraction in tumor heterogeneity and evolution G Satas, S Zaccaria, M El-Kebir, BJ Raphael Cell systems 12 (10), 1004-1018. e10, 2021 | 23 | 2021 |
The copy-number tree mixture deconvolution problem and applications to multi-sample bulk sequencing tumor data S Zaccaria, M El-Kebir, GW Klau, BJ Raphael Research in Computational Molecular Biology: 21st Annual International …, 2017 | 23 | 2017 |
On the inversion-indel distance E Willing, S Zaccaria, MDV Braga, J Stoye BMC bioinformatics 14, 1-10, 2013 | 21 | 2013 |
Identifying tumor clones in sparse single-cell mutation data MA Myers, S Zaccaria, BJ Raphael Bioinformatics 36 (Supplement_1), i186-i193, 2020 | 18 | 2020 |
CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction K Grigoriadis, A Huebner, A Bunkum, E Colliver, AM Frankell, MS Hill, ... Nature Protocols 19 (1), 159-183, 2024 | 15 | 2024 |
Structurally complex osteosarcoma genomes exhibit limited heterogeneity within individual tumors and across evolutionary time S Rajan, S Zaccaria, MV Cannon, M Cam, AC Gross, BJ Raphael, ... Cancer Research Communications 3 (4), 564-575, 2023 | 15 | 2023 |