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Isaac S. Harris
Isaac S. Harris
University of Rochester Medical Center, Wilmot Cancer Institute
Verified email at urmc.rochester.edu - Homepage
Title
Cited by
Cited by
Year
Regulation of cancer cell metabolism
RA Cairns, IS Harris, TW Mak
Nature Reviews Cancer 11 (2), 85-95, 2011
54192011
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
53342018
Modulation of oxidative stress as an anticancer strategy
C Gorrini, IS Harris, TW Mak
Nature reviews Drug discovery 12 (12), 931-947, 2013
33392013
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression
IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ...
Cancer cell 27 (2), 211-222, 2015
9142015
IDH1 (R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
M Sasaki, CB Knobbe, JC Munger, EF Lind, D Brenner, A Brüstle, ...
Nature 488 (7413), 656-659, 2012
6032012
Glutathione primes T cell metabolism for inflammation
TW Mak, M Grusdat, GS Duncan, C Dostert, Y Nonnenmacher, M Cox, ...
Immunity 46 (4), 675-689, 2017
4402017
The complex interplay between antioxidants and ROS in cancer
IS Harris, GM DeNicola
Trends in cell biology 30 (6), 440-451, 2020
4322020
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function
M Sasaki, CB Knobbe, M Itsumi, AJ Elia, IS Harris, IIC Chio, RA Cairns, ...
Genes & development 26 (18), 2038-2049, 2012
3432012
FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2
WJ Bakker, IS Harris, TW Mak
Molecular cell 28 (6), 941-953, 2007
3102007
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival
C Gorrini, PS Baniasadi, IS Harris, J Silvester, S Inoue, B Snow, PA Joshi, ...
Journal of Experimental Medicine 210 (8), 1529-1544, 2013
3022013
Differential glutamate metabolism in proliferating and quiescent mammary epithelial cells
JL Coloff, JP Murphy, CR Braun, IS Harris, LM Shelton, K Kami, SP Gygi, ...
Cell metabolism 23 (5), 867-880, 2016
2652016
Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance
N Takahashi, HY Chen, IS Harris, DG Stover, LM Selfors, RT Bronson, ...
Cancer cell 33 (6), 985-1003. e7, 2018
2082018
Cancer cell metabolism
RA Cairns, I Harris, S McCracken, TW Mak
Cold Spring Harbor symposia on quantitative biology 76, 299-311, 2011
1992011
Global proteomic assessment of the classical protein-tyrosine phosphatome and “Redoxome”
R Karisch, M Fernandez, P Taylor, C Virtanen, JR St-Germain, LL Jin, ...
Cell 146 (5), 826-840, 2011
1762011
Non-canonical glutamate-cysteine ligase activity protects against ferroptosis
YP Kang, A Mockabee-Macias, C Jiang, A Falzone, N Prieto-Farigua, ...
Cell metabolism 33 (1), 174-189. e7, 2021
1752021
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15
S Inoue, Z Hao, AJ Elia, D Cescon, L Zhou, J Silvester, B Snow, IS Harris, ...
Genes & development 27 (10), 1101-1114, 2013
1512013
TAp73 depletion accelerates aging through metabolic dysregulation
A Rufini, MV Niklison-Chirou, S Inoue, R Tomasini, IS Harris, A Marino, ...
Genes & development 26 (18), 2009-2014, 2012
1462012
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
S Shu, HJ Wu, YG Jennifer, R Zeid, IS Harris, B Jovanović, K Murphy, ...
Molecular cell 78 (6), 1096-1113. e8, 2020
1302020
Glutathione restricts serine metabolism to preserve regulatory T cell function
H Kurniawan, DG Franchina, L Guerra, L Bonetti, L Soriano-Baguet, ...
Cell metabolism 31 (5), 920-936. e7, 2020
1252020
Deubiquitinases maintain protein homeostasis and survival of cancer cells upon glutathione depletion
IS Harris, JE Endress, JL Coloff, LM Selfors, SK McBrayer, JM Rosenbluth, ...
Cell metabolism 29 (5), 1166-1181. e6, 2019
1252019
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