Challenges and opportunities for non-antibody scaffold drugs R Vazquez-Lombardi, TG Phan, C Zimmermann, D Lowe, L Jermutus, ... Drug discovery today 20 (10), 1271-1283, 2015 | 281 | 2015 |
Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity Z Sabouri, P Schofield, K Horikawa, E Spierings, D Kipling, KL Randall, ... Proceedings of the National Academy of Sciences 111 (25), E2567-E2575, 2014 | 271 | 2014 |
Transient expression of human antibodies in mammalian cells R Vazquez-Lombardi, D Nevoltris, A Luthra, P Schofield, C Zimmermann, ... Nature Protocols 13 (1), 99-117, 2018 | 98 | 2018 |
Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells R Vazquez-Lombardi, C Loetsch, D Zinkl, J Jackson, P Schofield, ... Nature communications 8 (1), 15373, 2017 | 79 | 2017 |
Molecular engineering of therapeutic cytokines R Vazquez-Lombardi, B Roome, D Christ Antibodies 2 (3), 426-451, 2013 | 77 | 2013 |
Advances in antibody-based therapy in oncology S Zinn, R Vazquez-Lombardi, C Zimmermann, P Sapra, L Jermutus, ... Nature Cancer 4 (2), 165-180, 2023 | 48 | 2023 |
A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients F Bieberich, R Vazquez-Lombardi, A Yermanos, RA Ehling, DM Mason, ... Frontiers in immunology 12, 701085, 2021 | 40 | 2021 |
IL-2 Shapes the Survival and Plasticity of IL-17–Producing γδ T Cells TM Corpuz, R Vazquez-Lombardi, JK Luong, J Warren, J Stolp, D Christ, ... The Journal of Immunology 199 (7), 2366-2376, 2017 | 32 | 2017 |
Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes A Yermanos, A Agrafiotis, R Kuhn, D Robbiani, J Yates, C Papadopoulou, ... NAR genomics and bioinformatics 3 (2), lqab023, 2021 | 29 | 2021 |
High-throughput T cell receptor engineering by functional screening identifies candidates with enhanced potency and specificity R Vazquez-Lombardi, JS Jung, FS Schlatter, A Mei, NR Mantuano, ... Immunity 55 (10), 1953-1966. e10, 2022 | 24 | 2022 |
Circumventing the stability-function trade-off in an engineered FN3 domain BT Porebski, PJ Conroy, N Drinkwater, P Schofield, R Vazquez-Lombardi, ... Protein Engineering, Design and Selection 29 (11), 541-550, 2016 | 21 | 2016 |
Cytosolic recognition of RNA drives the immune response to heterologous erythrocytes C Loetsch, J Warren, A Laskowski, R Vazquez-Lombardi, C Jandl, ... Cell Reports 21 (6), 1624-1638, 2017 | 18 | 2017 |
A functional screening strategy for engineering chimeric antigen receptors with reduced on-target, off-tumor activation RB Di Roberto, R Castellanos-Rueda, S Frey, D Egli, ... Molecular Therapy 28 (12), 2564-2576, 2020 | 15 | 2020 |
SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display RA Ehling, CR Weber, DM Mason, S Friedensohn, B Wagner, F Bieberich, ... Cell reports 38 (3), 2022 | 14 | 2022 |
Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2 RA Ehling, CR Weber, DM Mason, S Friedensohn, B Wagner, F Bieberich, ... BioRxiv, 2021.02. 12.430940, 2021 | 7 | 2021 |
CRISPR-targeted display of functional T cell receptors enables engineering of enhanced specificity and prediction of cross-reactivity R Vazquez-Lombardi, JS Jung, F Bieberich, E Kapetanovic, E Aznauryan, ... bioRxiv, 2020.06. 23.166363, 2020 | 7 | 2020 |
Expression of IgG monoclonals with engineered immune effector functions R Vazquez-Lombardi, D Nevoltris, R Rouet, D Christ Antibody Engineering: Methods and Protocols, 313-334, 2018 | 4 | 2018 |
Sequencing and affinity determination of antigen-specific B lymphocytes from peripheral blood P Schofield, R Vazquez-Lombardi, M Abdelatti, D Nevoltris, CC Goodnow, ... Antibody Engineering: Methods and Protocols, 287-309, 2018 | 2 | 2018 |
Multimodal single-cell profiling of T cell specificity and reactivity in lung cancer F Bieberich, R Vazquez-Lombardi, H Jin, KL Hong, P Herzig, M Trefny, ... bioRxiv, 2023.10. 04.560863, 2023 | | 2023 |
TCR-QR: IDENTIFYING TUMOUR-REACTIVE TCRS FOR PERSONALIZED T CELL THERAPIES F Bieberich, R Vazquez-Lombardi, S Reddy HUMAN GENE THERAPY 33 (7-8), A22-A22, 2022 | | 2022 |