Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development RD Bruno, VCO Njar Bioorganic & medicinal chemistry 15 (15), 5047-5060, 2007 | 346 | 2007 |
CYP17 inhibitors for prostate cancer therapy TS Vasaitis, RD Bruno, VCO Njar The Journal of steroid biochemistry and molecular biology 125 (1-2), 23-31, 2011 | 256 | 2011 |
3D bioprinted mammary organoids and tumoroids in human mammary derived ECM hydrogels PA Mollica, EN Booth-Creech, JA Reid, M Zamponi, SM Sullivan, ... Acta biomaterialia 95, 201-213, 2019 | 150 | 2019 |
Accessible bioprinting: adaptation of a low-cost 3D-printer for precise cell placement and stem cell differentiation JA Reid, PA Mollica, GD Johnson, RC Ogle, RD Bruno, PC Sachs Biofabrication 8 (2), 025017, 2016 | 123 | 2016 |
Reprogramming human cancer cells in the mouse mammary gland KM Bussard, CA Boulanger, BW Booth, RD Bruno, GH Smith Cancer research 70 (15), 6336-6343, 2010 | 107 | 2010 |
Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and … RD Bruno, TS Vasaitis, LK Gediya, P Purushottamachar, AM Godbole, ... Steroids 76 (12), 1268-1279, 2011 | 96 | 2011 |
17α-Hydroxylase/17, 20 lyase inhibitor VN/124-1 inhibits growth of androgen-independent prostate cancer cells via induction of the endoplasmic reticulum stress response RD Bruno, TD Gover, AM Burger, AM Brodie, VCO Njar Molecular cancer therapeutics 7 (9), 2828-2836, 2008 | 87 | 2008 |
A 3D bioprinter platform for mechanistic analysis of tumoroids and chimeric mammary organoids JA Reid, XL Palmer, PA Mollica, N Northam, PC Sachs, RD Bruno Scientific reports 9 (1), 7466, 2019 | 79 | 2019 |
Consistent and reproducible cultures of large-scale 3D mammary epithelial structures using an accessible bioprinting platform JA Reid, PA Mollica, RD Bruno, PC Sachs Breast Cancer Research 20, 1-13, 2018 | 68 | 2018 |
Tissue specific microenvironments: a key tool for tissue engineering and regenerative medicine PC Sachs, PA Mollica, RD Bruno Journal of biological engineering 11, 1-11, 2017 | 48 | 2017 |
Mammary extracellular matrix directs differentiation of testicular and embryonic stem cells to form functional mammary glands in vivo RD Bruno, JM Fleming, AL George, CA Boulanger, P Schedin, GH Smith Scientific reports 7 (1), 40196, 2017 | 45 | 2017 |
Galeterone and VNPT 55 disrupt Mnk‐eIF 4E to inhibit prostate cancer cell migration and invasion AK Kwegyir‐Afful, RD Bruno, P Purushottamachar, FN Murigi, VCO Njar The FEBS journal 283 (21), 3898-3918, 2016 | 45 | 2016 |
The mouse mammary microenvironment redirects mesoderm-derived bone marrow cells to a mammary epithelial progenitor cell fate CA Boulanger, RD Bruno, M Rosu-Myles, GH Smith Stem cells and development 21 (6), 948-954, 2012 | 43 | 2012 |
Potent anti-prostate cancer agents derived from a novel androgen receptor down-regulating agent P Purushottamachar, A Khandelwal, TS Vasaitis, RD Bruno, LK Gediya, ... Bioorganic & medicinal chemistry 16 (7), 3519-3529, 2008 | 39 | 2008 |
First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents P Purushottamachar, A Khandelwal, P Chopra, N Maheshwari, LK Gediya, ... Bioorganic & medicinal chemistry 15 (10), 3413-3421, 2007 | 35 | 2007 |
Reprogramming non-mammary and cancer cells in the developing mouse mammary gland RD Bruno, GH Smith Seminars in cell & developmental biology 23 (5), 591-598, 2012 | 32 | 2012 |
Embryonic stem cells are redirected to non-tumorigenic epithelial cell fate by interaction with the mammary microenvironment CA Boulanger, RD Bruno, DL Mack, M Gonzales, NP Castro, DS Salomon, ... PloS one 8 (4), e62019, 2013 | 31 | 2013 |
Functional characterization of stem cell activity in the mouse mammary gland RD Bruno, GH Smith Stem Cell Reviews and Reports 7, 238-247, 2011 | 29 | 2011 |
DNA methylation leads to DNA repair gene down-regulation and trinucleotide repeat expansion in patient-derived huntington disease cells PA Mollica, JA Reid, RC Ogle, PC Sachs, RD Bruno The American journal of pathology 186 (7), 1967-1976, 2016 | 22 | 2016 |
Notch-induced mammary tumorigenesis does not involve the lobule-limited epithelial progenitor RD Bruno, CA Boulanger, GH Smith Oncogene 31 (1), 60-67, 2012 | 22 | 2012 |