| Systematic humanization of yeast genes reveals conserved functions and genetic modularity AH Kachroo, JM Laurent, CM Yellman, AG Meyer, CO Wilke, EM Marcotte Science 348 (6237), 921-925, 2015 | 534 | 2015 |
| Protein abundances are more conserved than mRNA abundances across diverse taxa JM Laurent, C Vogel, T Kwon, SA Craig, DR Boutz, HK Huse, K Nozue, ... Proteomics 10 (23), 4209-4212, 2010 | 165 | 2010 |
| Efforts to make and apply humanized yeast JM Laurent, JH Young, AH Kachroo, EM Marcotte Briefings in functional genomics 15 (2), 155-163, 2016 | 132 | 2016 |
| Single-step precision genome editing in yeast using CRISPR-Cas9 A Akhmetov, JM Laurent, J Gollihar, EC Gardner, RK Garge, AD Ellington, ... Bio-protocol 8 (6), e2765-e2765, 2018 | 61 | 2018 |
| Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs JM Laurent, RK Garge, AI Teufel, CO Wilke, AH Kachroo, EM Marcotte PLoS biology 18 (5), e3000627, 2020 | 55* | 2020 |
| Prediction of gene-phenotype associations in humans, mice, and plants using phenologs JO Woods, UM Singh-Blom, JM Laurent, KL McGary, EM Marcotte BMC bioinformatics 14, 1-17, 2013 | 53 | 2013 |
| A versatile platform for locus-scale genome rewriting and verification R Brosh, JM Laurent, R Ordoñez, E Huang, MS Hogan, AM Hitchcock, ... Proceedings of the National Academy of Sciences 118 (10), e2023952118, 2021 | 45 | 2021 |
| Systematic bacterialization of yeast genes identifies a near-universally swappable pathway AH Kachroo, JM Laurent, A Akhmetov, M Szilagyi-Jones, CD McWhite, ... Elife 6, e25093, 2017 | 40 | 2017 |
| The many nuanced evolutionary consequences of duplicated genes AI Teufel, MM Johnson, JM Laurent, AH Kachroo, EM Marcotte, CO Wilke Molecular biology and evolution 36 (2), 304-314, 2019 | 33 | 2019 |
| Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes RK Garge, JM Laurent, AH Kachroo, EM Marcotte Genetics 215 (4), 1153-1169, 2020 | 26 | 2020 |
| Assessment of potential SARS-CoV-2 virus integration into human genome reveals no significant impact on RT-qPCR COVID-19 testing E Briggs, W Ward, S Rey, D Law, K Nelson, M Bois, N Ostrov, HH Lee, ... Proceedings of the National Academy of Sciences 118 (44), e2113065118, 2021 | 18 | 2021 |
| CREEPY: CRISPR-mediated editing of synthetic episomes in yeast Y Zhao, C Coelho, S Lauer, M Majewski, JM Laurent, R Brosh, JD Boeke Nucleic acids research 51 (13), e72-e72, 2023 | 11* | 2023 |
| Big DNA as a tool to dissect an age-related macular degeneration-associated haplotype JM Laurent, X Fu, S German, MT Maurano, K Zhang, JD Boeke Precision Clinical Medicine 2 (1), 1-7, 2019 | 10 | 2019 |
| Lab-bench: Measuring capabilities of language models for biology research JM Laurent, JD Janizek, M Ruzo, MM Hinks, MJ Hammerling, ... arXiv preprint arXiv:2407.10362, 2024 | 8 | 2024 |
| Probing the dark matter of the human genome with big DNA JM Laurent, S Pinglay, L Mitchell, R Brosh The Biochemist 41 (3), 46-48, 2019 | 5 | 2019 |
| Rapid, scalable, combinatorial genome engineering by marker-less enrichment and recombination of genetically engineered loci in yeast M Abdullah, BM Greco, JM Laurent, RK Garge, DR Boutz, M Vandeloo, ... Cell Reports Methods 3 (5), 2023 | 4 | 2023 |
| Language agents achieve superhuman synthesis of scientific knowledge MD Skarlinski, S Cox, JM Laurent, JD Braza, M Hinks, MJ Hammerling, ... arXiv preprint arXiv:2409.13740, 2024 | 3 | 2024 |
| Wikicrow: Automating synthesis of human scientific knowledge S Cox, M Hammerling, J Lála, J Laurent, S Rodriques, M Rubashkin, ... Future House, 2023 | 3 | 2023 |
| Development and scaling of a sequencing pipeline for genomic surveillance of SARS-CoV-2 in New York City MJ Hammerling, SC Kang, W Ward, IF Escapa, P Bugga, C Del Castillo, ... medRxiv, 2022.05. 25.22273991, 2022 | 3 | 2022 |
| Methods and compositions for rapid and high throughput diagnosis JD Boeke, J Laurent, A Martin, M Paolo US Patent 11,667,962, 2023 | 1 | 2023 |
Edward MarcotteProfessor of Molecular Biosciences, University of Texas at AustinVerified email at utexas.edu
