| Integrated, high-throughput, multiomics platform enables data-driven construction of cellular responses and reveals global drug mechanisms of action JL Norris, MA Farrow, DB Gutierrez, LD Palmer, N Muszynski, SD Sherrod, ... Journal of proteome research 16 (3), 1364-1375, 2017 | 45 | 2017 |
| Activated oncogenic pathway modifies iron network in breast epithelial cells: a dynamic modeling perspective J Chifman, S Arat, Z Deng, E Lemler, JC Pino, LA Harris, MA Kochen, ... PLoS computational biology 13 (2), e1005352, 2017 | 28 | 2017 |
| GPU-powered model analysis with PySB/cupSODA LA Harris, MS Nobile, JC Pino, ALR Lubbock, D Besozzi, G Mauri, ... Bioinformatics 33 (21), 3492-3494, 2017 | 22 | 2017 |
| CASP11–an evaluation of a modular BCL:: fold-based protein structure prediction pipeline AW Fischer, S Heinze, DK Putnam, B Li, JC Pino, Y Xia, CF Lopez, ... PLoS One 11 (4), e0152517, 2016 | 18 | 2016 |
| Chipper: Open‐source software for semi‐automated segmentation and analysis of birdsong and other natural sounds AM Searfoss, JC Pino, N Creanza Methods in Ecology and Evolution 11 (4), 524-531, 2020 | 16 | 2020 |
| Folding propensity of intrinsically disordered proteins by osmotic stress AL Mansouri, LN Grese, EL Rowe, JC Pino, SC Chennubhotla, ... Molecular BioSystems 12 (12), 3695-3701, 2016 | 16 | 2016 |
| Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML SJC Gosline, C Tognon, M Nestor, S Joshi, R Modak, A Damnernsawad, ... Clinical proteomics 19 (1), 30, 2022 | 14 | 2022 |
| Probability-based mechanisms in biological networks with parameter uncertainty OO Ortega, M Ozen, BA Wilson, JC Pino, MW Irvin, GV Ildefonso, ... bioRxiv, 2021.01. 26.428266, 2021 | 7 | 2021 |
| CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors J Wang, A Calizo, L Zhang, JC Pino, Y Lyu, K Pollard, X Zhang, ... Science Advances 9 (47), eadg8876, 2023 | 6 | 2023 |
| Proteome Mapping of the Human Pancreatic Islet Microenvironment Reveals Endocrine–Exocrine Signaling Sphere of Influence SJC Gosline, M Veličković, JC Pino, LZ Day, IK Attah, AC Swensen, ... Molecular & Cellular Proteomics 22 (8), 2023 | 6 | 2023 |
| Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology AT Larsson, H Bhatia, A Calizo, K Pollard, X Zhang, E Conniff, JF Tibbitts, ... Neuro-oncology 25 (11), 2044-2057, 2023 | 5 | 2023 |
| Processes in DNA damage response from a whole-cell multi-omics perspective JC Pino, ALR Lubbock, LA Harris, DB Gutierrez, MA Farrow, N Muszynski, ... Iscience 25 (11), 2022 | 5 | 2022 |
| Coupling Microdroplet-Based Sample Preparation, Multiplexed Isobaric Labeling, and Nanoflow Peptide Fractionation for Deep Proteome Profiling of the Tissue Microenvironment M Veličković, TL Fillmore, IK Attah, C Posso, JC Pino, R Zhao, ... Analytical Chemistry 96 (32), 12973-12982, 2024 | 3 | 2024 |
| Mapping the proteogenomic landscape enables prediction of drug response in acute myeloid leukemia JC Pino, C Posso, SK Joshi, M Nestor, J Moon, JR Hansen, ... Cell Reports Medicine 5 (1), 2024 | 3 | 2024 |
| CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors J Wang, A Calizo, L Zhang, JC Pino, Y Lyu, K Pollard, X Zhang, ... bioRxiv, 2023 | 3 | 2023 |
| Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology H Bhatia, AT Larsson, A Calizo, K Pollard, X Zhang, E Conniff, JF Tibbitts, ... bioRxiv, 2022.04. 29.490078, 2022 | 2 | 2022 |
| Selective inhibition of JAK1 primes STAT5-driven human leukemia cells for ATRA-induced differentiation HE Ramsey, K Stengel, JC Pino, G Johnston, M Childress, AE Gorska, ... Targeted oncology 16, 663-674, 2021 | 2 | 2021 |
| High-throughput, multi-omics approach to determine and validate de novo global mechanisms of action for drugs and toxins R Caprioli, J Wikswo, J McLean, E Skaar, JL Norris, DB Lacy, S Sherrod, ... US Patent 10,607,721, 2020 | 2 | 2020 |
| Signal execution modes emerge in biochemical reaction networks calibrated to experimental data OO Ortega, M Ozen, BA Wilson, JC Pino, MW Irvin, GV Ildefonso, ... Iscience 27 (6), 2024 | 1 | 2024 |
| A computational framework to explore cellular response mechanisms from multi-omics datasets JC Pino, ALR Lubbock, LA Harris, DB Gutierrez, MA Farrow, N Muszynski, ... bioRxiv, 2020.03. 02.974121, 2020 | 1 | 2020 |
Carlos LopezLead, Multiscale Modeling and Principal ScientistVerified email at altoslabs.com
