Chromosomal instability drives metastasis through a cytosolic DNA response SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ... Nature 553 (7689), 467-472, 2018 | 1345 | 2018 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 441 | 2020 |
Regenerative lineages and immune-mediated pruning in lung cancer metastasis AM Laughney, J Hu, NR Campbell, SF Bakhoum, M Setty, VP Lavallée, ... Nature medicine 26 (2), 259-269, 2020 | 355 | 2020 |
Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle MA Miller, S Gadde, C Pfirschke, C Engblom, MM Sprachman, RH Kohler, ... Science translational medicine 7 (314), 314ra183-314ra183, 2015 | 352 | 2015 |
L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer K Ganesh, H Basnet, Y Kaygusuz, AM Laughney, L He, R Sharma, ... Nature cancer 1 (1), 28-45, 2020 | 194 | 2020 |
Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution. BSF Laughney AM, Elizalde S, Genovese G Cell Reports, 2015 | 139 | 2015 |
Spectral discrimination of breast pathologies in situusing spatial frequency domain imaging AM Laughney, V Krishnaswamy, EJ Rizzo, MC Schwab, RJ Barth, ... Breast Cancer Research 15, 1-13, 2013 | 111 | 2013 |
Non-cell-autonomous cancer progression from chromosomal instability J Li, MJ Hubisz, EM Earlie, MA Duran, C Hong, AA Varela, E Lettera, ... Nature 620 (7976), 1080-1088, 2023 | 91 | 2023 |
Numerical chromosomal instability mediates susceptibility to radiation treatment SF Bakhoum, L Kabeche, MD Wood, CD Laucius, D Qu, AM Laughney, ... Nature communications 6 (1), 5990, 2015 | 89 | 2015 |
Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin AM Laughney, E Kim, MM Sprachman, MA Miller, RH Kohler, KS Yang, ... Science translational medicine 6 (261), 261ra152-261ra152, 2014 | 85 | 2014 |
Cancer metastasis as a non-healing wound M Deyell, CS Garris, AM Laughney British journal of cancer 124 (9), 1491-1502, 2021 | 78 | 2021 |
System analysis of spatial frequency domain imaging for quantitative mapping of surgically resected breast tissues AM Laughney, V Krishnaswamy, TB Rice, DJ Cuccia, RJ Barth, ... Journal of biomedical optics 18 (3), 036012-036012, 2013 | 65 | 2013 |
Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity CP Santos, E Lapi, J Martínez de Villarreal, L Álvaro-Espinosa, ... Nature communications 10 (1), 4407, 2019 | 54 | 2019 |
Scatter spectroscopic imaging distinguishes between breast pathologies in tissues relevant to surgical margin assessment AM Laughney, V Krishnaswamy, EJ Rizzo, MC Schwab, RJ Barth, ... Clinical Cancer Research 18 (22), 6315-6325, 2012 | 54 | 2012 |
High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging XP Xie, DR Laks, D Sun, A Poran, AM Laughney, Z Wang, J Sam, ... Proceedings of the National Academy of Sciences 117 (49), 31448-31458, 2020 | 53 | 2020 |
Adult human glioblastomas harbor radial glia-like cells R Wang, R Sharma, X Shen, AM Laughney, K Funato, PJ Clark, ... Stem Cell Reports 14 (2), 338-350, 2020 | 51 | 2020 |
Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression MF Bakhoum, JH Francis, A Agustinus, EM Earlie, M Di Bona, ... Nature communications 12 (1), 5402, 2021 | 46 | 2021 |
Automated classification of breast pathology using local measures of broadband reflectance PBW Laughney AM, Krishnaswamy V, Garcia-Allende PB Journal of biomedical optics 15 (6), 066019-066019-12, 2010 | 38 | 2010 |
Measurement of pressure-displacement kinetics of hemoglobin in normal breast tissue with near-infrared spectral imaging S Jiang, BW Pogue, AM Laughney, CA Kogel, KD Paulsen Applied optics 48 (10), D130-D136, 2009 | 37 | 2009 |
A Markov chain for numerical chromosomal instability in clonally expanding populations S Elizalde, AM Laughney, SF Bakhoum PLoS computational biology 14 (9), e1006447, 2018 | 32 | 2018 |