Deeptak Verma
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Design of an in vitro biocatalytic cascade for the manufacture of islatravir
MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, ...
Science 366 (6470), 1255-1259, 2019
Deep dive into machine learning models for protein engineering
Y Xu, D Verma, RP Sheridan, A Liaw, J Ma, NM Marshall, J McIntosh, ...
Journal of chemical information and modeling 60 (6), 2773-2790, 2020
Engineered ribosyl-1-kinase enables concise synthesis of molnupiravir, an antiviral for COVID-19
JA McIntosh, T Benkovics, SM Silverman, MA Huffman, J Kong, ...
ACS Central Science 7 (12), 1980-1985, 2021
A kinase-cGAS cascade to synthesize a therapeutic STING activator
JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ...
Nature 603 (7901), 439-444, 2022
Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo
H Zhao, D Verma, W Li, Y Choi, C Ndong, SN Fiering, C Bailey-Kellogg, ...
Chemistry & biology 22 (5), 629-639, 2015
Changes in lysozyme flexibility upon mutation are frequent, large and long-ranged
D Verma, DJ Jacobs, DR Livesay
PLoS computational biology 8 (3), e1002409, 2012
Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity
RS Salvat, D Verma, AS Parker, JR Kirsch, SA Brooks, C Bailey-Kellogg, ...
Proceedings of the National Academy of Sciences 114 (26), E5085-E5093, 2017
Docking mode of delvardine and its analogues into the p66 domain of HIV-1 reverse transcriptase: screening using molecular mechanics-generalized born/surface area and …
D Sengupta, D Verma, PK Naik
Journal of biosciences 32, 1307-1316, 2007
Using enzymes to tame nitrogen-centred radicals for enantioselective hydroamination
Y Ye, J Cao, DG Oblinsky, D Verma, CK Prier, GD Scholes, TK Hyster
Nature chemistry 15 (2), 206-212, 2023
Diverse catalytic reactions for the stereoselective synthesis of cyclic dinucleotide MK-1454
T Benkovics, F Peng, EM Phillips, C An, RS Bade, CK Chung, ZEX Dance, ...
Journal of the American Chemical Society 144 (13), 5855-5863, 2022
EpiSweep: Computationally driven reengineering of therapeutic proteins to reduce immunogenicity while maintaining function
Y Choi, D Verma, KE Griswold, C Bailey-Kellogg
Computational Protein Design, 375-398, 2017
Variations within class-A β-lactamase physiochemical properties reflect evolutionary and environmental patterns, but not antibiotic specificity
D Verma, DJ Jacobs, DR Livesay
PLoS computational biology 9 (7), e1003155, 2013
Globally deimmunized lysostaphin evades human immune surveillance and enables highly efficacious repeat dosing
H Zhao, SA Brooks, S Eszterhas, S Heim, L Li, YQ Xiong, Y Fang, ...
Science advances 6 (36), eabb9011, 2020
Characterization of potent RSV neutralizing antibodies isolated from human memory B cells and identification of diverse RSV/hMPV cross-neutralizing epitopes
X Xiao, A Tang, KS Cox, Z Wen, C Callahan, NL Sullivan, DD Nahas, ...
MAbs 11 (8), 1415-1427, 2019
Evolving to an ideal synthesis of molnupiravir, an investigational treatment for COVID-19
T Benkovics, J McIntosh, S Silverman, J Kong, P Maligres, T Itoh, H Yang, ...
Thermodynamic stability and flexibility characteristics of antibody fragment complexes
T Li, D Verma, M B Tracka, J Casas-Finet, D R Livesay, D J Jacobs
Protein and peptide letters 21 (8), 752-765, 2014
Ensemble properties of network rigidity reveal allosteric mechanisms
DJ Jacobs, DR Livesay, JM Mottonen, OK Vorov, AY Istomin, D Verma
Allostery: Methods and Protocols, 279-304, 2012
Structure‐based design of combinatorial mutagenesis libraries
D Verma, G Grigoryan, C Bailey‐Kellogg
Protein science 24 (5), 895-908, 2015
Predicting the melting point of human C-type lysozyme mutants
D Verma, D J Jacobs, D R Livesay
Current Protein and Peptide Science 11 (7), 562-572, 2010
Canada, KA; Bulger, PG; Sherry, BD; Truppo, M. D.; Ruck, RT; Campeau, L.-C.; Bennett, DJ; Humphrey, GR; Campos, KR; Maddess, ML A Kinase-cGAS Cascade to Synthesize a …
JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ...
Nature 603 (7901), 439-444, 2022
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