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Andrew M. Intlekofer, M.D., Ph.D.
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Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
AM Intlekofer, N Takemoto, EJ Wherry, SA Longworth, JT Northrup, ...
Nature Immunology 6 (12), 1236-1244, 2005
14742005
Asymmetric T lymphocyte division in the initiation of adaptive immune responses
JT Chang, VR Palanivel, I Kinjyo, F Schambach, AM Intlekofer, ...
Science 315 (5819), 1687, 2007
10702007
A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection
H Shin, SD Blackburn, AM Intlekofer, C Kao, JM Angelosanto, SL Reiner, ...
Immunity 31 (2), 309-320, 2009
5692009
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
C Kao, KJ Oestreich, MA Paley, A Crawford, JM Angelosanto, MAA Ali, ...
Nature Immunology 12 (7), 663-671, 2011
5472011
Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche
A Banerjee, SM Gordon, AM Intlekofer, MA Paley, EC Mooney, T Lindsten, ...
The Journal of Immunology 185 (9), 4988-4992, 2010
5402010
Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin
AM Intlekofer, A Banerjee, N Takemoto, SM Gordon, CS DeJong, H Shin, ...
Science 321 (5887), 408, 2008
4952008
Hypoxia induces production of L-2-hydroxyglutarate
AM Intlekofer, RG Dematteo, S Venneti, LWS Finley, C Lu, AR Judkins, ...
Cell metabolism 22 (2), 304-311, 2015
4722015
Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation
N Takemoto, AM Intlekofer, JT Northrup, EJ Wherry, SL Reiner
The Journal of Immunology 177 (11), 7515-7519, 2006
4662006
At the bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy
AM Intlekofer, CB Thompson
Journal of Leukocyte Biology, 2013
4452013
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells
AM Intlekofer, N Takemoto, C Kao, A Banerjee, F Schambach, ...
The Journal of Experimental Medicine 204 (9), 2015-2021, 2007
3682007
The public repository of xenografts enables discovery and randomized phase II-like trials in mice
EC Townsend, MA Murakami, A Christodoulou, AL Christie, J Köster, ...
Cancer cell 29 (4), 574-586, 2016
3322016
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms
R Rampal, J Ahn, O Abdel-Wahab, M Nahas, K Wang, D Lipson, GA Otto, ...
Proceedings of the National Academy of Sciences 111 (50), E5401-E5410, 2014
3132014
As extracellular glutamine levels decline, asparagine becomes an essential amino acid
NN Pavlova, S Hui, JM Ghergurovich, J Fan, AM Intlekofer, RM White, ...
Cell metabolism 27 (2), 428-438. e5, 2018
2872018
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
J He, O Abdel-Wahab, MK Nahas, K Wang, RK Rampal, AM Intlekofer, ...
Blood, The Journal of the American Society of Hematology 127 (24), 3004-3014, 2016
2852016
Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations
AM Intlekofer, AH Shih, B Wang, A Nazir, AS Rustenburg, SK Albanese, ...
Nature 559 (7712), 125-129, 2018
2662018
Metabolic signatures of cancer cells and stem cells
AM Intlekofer, LWS Finley
Nature metabolism 1 (2), 177-188, 2019
2632019
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH
AM Intlekofer, B Wang, H Liu, H Shah, C Carmona-Fontaine, ...
Nature chemical biology 13 (5), 494-500, 2017
2482017
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
Y Yashiro-Ohtani, Y He, T Ohtani, ME Jones, O Shestova, L Xu, TC Fang, ...
Genes & Development 23 (14), 1665-1676, 2009
2142009
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis
A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ...
Nature 574 (7777), 273-277, 2019
1882019
Induction of sarcomas by mutant IDH2
C Lu, S Venneti, A Akalin, F Fang, PS Ward, RG DeMatteo, AM Intlekofer, ...
Genes & development 27 (18), 1986-1998, 2013
1832013
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Articles 1–20