A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples VL Dao Thi, K Herbst, K Boerner, M Meurer, LPM Kremer, D Kirrmaier, ... Science translational medicine 12 (556), eabc7075, 2020 | 695 | 2020 |
CRISPR/Cas9‐mediated genome engineering: an adeno‐associated viral (AAV) vector toolbox E Senís, C Fatouros, S Große, E Wiedtke, D Niopek, AK Mueller, K Börner, ... Biotechnology journal 9 (11), 1402-1412, 2014 | 353 | 2014 |
Cone-shaped HIV-1 capsids are transported through intact nuclear pores V Zila, E Margiotta, B Turoňová, TG Müller, CE Zimmerli, S Mattei, ... Cell 184 (4), 1032-1046. e18, 2021 | 293 | 2021 |
Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments S Fanucchi, ET Fok, E Dalla, Y Shibayama, K Börner, EY Chang, ... Nature genetics 51 (1), 138-150, 2019 | 269 | 2019 |
Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver D Grimm, L Wang, JS Lee, N Schürmann, S Gu, K Börner, TA Storm, ... The Journal of clinical investigation 120 (9), 3106-3119, 2010 | 263 | 2010 |
Engineered anti-CRISPR proteins for optogenetic control of CRISPR–Cas9 F Bubeck, MD Hoffmann, Z Harteveld, S Aschenbrenner, A Bietz, ... Nature methods 15 (11), 924-927, 2018 | 216 | 2018 |
HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the nuclear pore complex DA Bejarano, K Peng, V Laketa, K Börner, KL Jost, B Lucic, B Glass, ... Elife 8, e41800, 2019 | 197 | 2019 |
SARS-CoV-2 RNA extraction using magnetic beads for rapid large-scale testing by RT-qPCR and RT-LAMP S Klein, TG Müller, D Khalid, V Sonntag-Buck, AM Heuser, B Glass, ... Viruses 12 (8), 863, 2020 | 125 | 2020 |
Cell-specific CRISPR–Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins MD Hoffmann, S Aschenbrenner, S Grosse, K Rapti, C Domenger, ... Nucleic acids research 47 (13), e75-e75, 2019 | 101 | 2019 |
Nanobody-enhanced targeting of AAV gene therapy vectors AM Eichhoff, K Börner, B Albrecht, W Schäfer, N Baum, F Haag, J Körbelin, ... Molecular Therapy-Methods & Clinical Development 15, 211-220, 2019 | 86 | 2019 |
Relevance of assembly-activating protein for adeno-associated virus vector production and capsid protein stability in mammalian and insect cells S Grosse, M Penaud-Budloo, AK Herrmann, K Börner, J Fakhiri, V Laketa, ... Journal of virology 91 (20), 10.1128/jvi. 01198-17, 2017 | 86 | 2017 |
Synthetic AAV/CRISPR vectors for blocking HIV‐1 expression in persistently infected astrocytes C Kunze, K Börner, E Kienle, T Orschmann, E Rusha, M Schneider, ... Glia 66 (2), 413-427, 2018 | 76 | 2018 |
Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines K Börner, D Niopek, G Cotugno, M Kaldenbach, T Pankert, J Willemsen, ... Nucleic acids research 41 (21), e199-e199, 2013 | 74 | 2013 |
Type I interferon regulates the expression of long non-coding RNAs E Carnero, M Barriocanal, V Segura, E Guruceaga, C Prior, K Börner, ... Frontiers in immunology 5, 548, 2014 | 68 | 2014 |
Pre-arrayed pan-AAV peptide display libraries for rapid single-round screening K Börner, E Kienle, LY Huang, J Weinmann, A Sacher, P Bayer, C Stüllein, ... Molecular therapy 28 (4), 1016-1032, 2020 | 67 | 2020 |
Low-level shRNA cytotoxicity can contribute to MYC-induced hepatocellular carcinoma in adult mice S Beer, DI Bellovin, JS Lee, K Komatsubara, LS Wang, H Koh, K Börner, ... Molecular Therapy 18 (1), 161-170, 2010 | 65 | 2010 |
From experimental setup to bioinformatics: An RNAi screening platform to identify host factors involved in HIV‐1 replication K Börner, J Hermle, C Sommer, NP Brown, B Knapp, B Glass, J Kunkel, ... Biotechnology Journal: Healthcare Nutrition Technology 5 (1), 39-49, 2010 | 59 | 2010 |
Proteome analysis of the HIV-1 Gag interactome CE Engeland, NP Brown, K Börner, M Schümann, E Krause, L Kaderali, ... Virology 460, 194-206, 2014 | 58 | 2014 |
Engineering and evolution of synthetic adeno-associated virus (AAV) gene therapy vectors via DNA family shuffling E Kienle, E Senís, K Börner, D Niopek, E Wiedtke, S Grosse, D Grimm Journal of visualized experiments: JoVE, 3819, 2012 | 48 | 2012 |
Detailed characterization of early HIV-1 replication dynamics in primary human macrophages DA Bejarano, MC Puertas, K Börner, J Martinez-Picado, B Müller, ... Viruses 10 (11), 620, 2018 | 40 | 2018 |