BACE1, a major determinant of selective vulnerability of the brain to amyloid-β amyloidogenesis, is essential for cognitive, emotional, and synaptic functions FM Laird, H Cai, AV Savonenko, MH Farah, K He, T Melnikova, H Wen, ... Journal of Neuroscience 25 (50), 11693-11709, 2005 | 679 | 2005 |
Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease JL Jankowsky, T Melnikova, DJ Fadale, GM Xu, HH Slunt, V Gonzales, ... Journal of Neuroscience 25 (21), 5217-5224, 2005 | 632 | 2005 |
Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to β-amyloid deposition and neurotransmitter abnormalities A Savonenko, GM Xu, T Melnikova, JL Morton, V Gonzales, MPF Wong, ... Neurobiology of disease 18 (3), 602-617, 2005 | 473 | 2005 |
Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice AV Savonenko, T Melnikova, FM Laird, KA Stewart, DL Price, PC Wong Proceedings of the National Academy of Sciences 105 (14), 5585-5590, 2008 | 341 | 2008 |
Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice KI Andreasson, A Savonenko, S Vidensky, JJ Goellner, Y Zhang, ... Journal of Neuroscience 21 (20), 8198-8209, 2001 | 284 | 2001 |
A mouse model of blast injury to brain: initial pathological, neuropathological, and behavioral characterization VE Koliatsos, I Cernak, L Xu, Y Song, A Savonenko, BJ Crain, ... Journal of Neuropathology & Experimental Neurology 70 (5), 399-416, 2011 | 269 | 2011 |
Persistent amyloidosis following suppression of Aβ production in a transgenic model of Alzheimer disease JL Jankowsky, HH Slunt, V Gonzales, AV Savonenko, JC Wen, ... PLoS medicine 2 (12), e355, 2005 | 246 | 2005 |
Effectiveness of estrogen replacement in restoration of cognitive function after long-term estrogen withdrawal in aging rats AL Markowska, AV Savonenko Journal of neuroscience 22 (24), 10985-10995, 2002 | 240 | 2002 |
Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease Y Liu, MJ Yoo, A Savonenko, W Stirling, DL Price, DR Borchelt, ... Journal of Neuroscience 28 (51), 13805-13814, 2008 | 222 | 2008 |
Morphometry of the human substantia nigra in ageing and Parkinson’s disease G Rudow, R O’Brien, AV Savonenko, SM Resnick, AB Zonderman, ... Acta neuropathologica 115, 461-470, 2008 | 216 | 2008 |
NPTX2 and cognitive dysfunction in Alzheimer’s Disease MF Xiao, D Xu, MT Craig, KA Pelkey, CC Chien, Y Shi, J Zhang, ... Elife 6, e23798, 2017 | 194 | 2017 |
The cognitive effects of ovariectomy and estrogen replacement are modulated by aging AV Savonenko, AL Markowska Neuroscience 119 (3), 821-830, 2003 | 168 | 2003 |
PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R) AG Horti, R Naik, CA Foss, I Minn, V Misheneva, Y Du, Y Wang, ... Proceedings of the National Academy of Sciences 116 (5), 1686-1691, 2019 | 162 | 2019 |
Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer’s disease in a sex-dimorphic pattern T Melnikova, A Savonenko, Q Wang, X Liang, T Hand, L Wu, ... Neuroscience 141 (3), 1149-1162, 2006 | 151 | 2006 |
RETRACTED: Enhanced polyubiquitination of shank3 and NMDA receptor in a mouse model of Autism MA Bangash, JM Park, T Melnikova, D Wang, SK Jeon, D Lee, S Syeda, ... Cell 145 (5), 758-772, 2011 | 143 | 2011 |
Synthesis and biodistribution of [11C] A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2) AG Horti, Y Gao, HT Ravert, P Finley, H Valentine, DF Wong, CJ Endres, ... Bioorganic & medicinal chemistry 18 (14), 5202-5207, 2010 | 122 | 2010 |
Inhibition of neutral sphingomyelinase‐2 perturbs brain sphingolipid balance and spatial memory in mice N Tabatadze, A Savonenko, H Song, VVR Bandaru, M Chu, NJ Haughey Journal of neuroscience research 88 (13), 2940-2951, 2010 | 115 | 2010 |
Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice G Schilling, AV Savonenko, A Klevytska, JL Morton, SM Tucker, M Poirier, ... Human molecular genetics 13 (15), 1599-1610, 2004 | 115 | 2004 |
Cannabinoid CB2 receptors in a mouse model of Aβ amyloidosis: immunohistochemical analysis and suitability as a PET biomarker of neuroinflammation AV Savonenko, T Melnikova, Y Wang, H Ravert, Y Gao, J Koppel, D Lee, ... PloS one 10 (6), e0129618, 2015 | 114 | 2015 |
Amyloid precursor protein increases cortical neuron size in transgenic mice ES Oh, AV Savonenko, JF King, SMF Tucker, GL Rudow, G Xu, ... Neurobiology of aging 30 (8), 1238-1244, 2009 | 110 | 2009 |