Interleukin-1β causes acute lung injury via αvβ5 and αvβ6 integrin–dependent mechanisms MT Ganter, J Roux, B Miyazawa, M Howard, JA Frank, G Su, D Sheppard, ... Circulation research 102 (7), 804-812, 2008 | 248 | 2008 |
Interleukin-1β decreases expression of the epithelial sodium channel α-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway J Roux, H Kawakatsu, B Gartland, M Pespeni, D Sheppard, MA Matthay, ... Journal of Biological Chemistry 280 (19), 18579-18589, 2005 | 201 | 2005 |
Transforming growth factor-β1 decreases expression of the epithelial sodium channel αENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent … J Frank, J Roux, H Kawakatsu, G Su, A Dagenais, Y Berthiaume, ... Journal of Biological Chemistry 278 (45), 43939-43950, 2003 | 184 | 2003 |
Fractional killing arises from cell‐to‐cell variability in overcoming a caspase activity threshold J Roux, M Hafner, S Bandara, JJ Sims, H Hudson, D Chai, PK Sorger Molecular systems biology 11 (5), 803, 2015 | 161 | 2015 |
Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury MT Ganter, LB Ware, M Howard, J Roux, B Gartland, MA Matthay, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 291 (3 …, 2006 | 118 | 2006 |
Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes DA Flusberg, J Roux, SL Spencer, PK Sorger Molecular biology of the cell 24 (14), 2186-2200, 2013 | 103 | 2013 |
Stress-induced inhibition of the NF-κB signaling pathway results from the insolubilization of the IκB kinase complex following its dissociation from heat shock protein 90 JF Pittet, H Lee, M Pespeni, A O’Mahony, J Roux, WJ Welch The journal of Immunology 174 (1), 384-394, 2005 | 88 | 2005 |
Mammalian osmolytes and S-nitrosoglutathione promote ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) protein maturation and function M Howard, H Fischer, J Roux, BC Santos, SR Gullans, PH Yancey, ... Journal of Biological Chemistry 278 (37), 35159-35167, 2003 | 80 | 2003 |
Reactive nitrogen species inhibit alveolar epithelial fluid transport after hemorrhagic shock in rats JF Pittet, LN Lu, DG Morris, K Modelska, WJ Welch, HV Carey, J Roux, ... The Journal of Immunology 166 (10), 6301-6310, 2001 | 79 | 2001 |
HMGB1 accelerates alveolar epithelial repair via an IL-1β-and αvβ6 integrin-dependent activation of TGF-β1 JF Pittet, H Koh, X Fang, K Iles, S Christiaans, N Anjun, BM Wagener, ... PLoS One 8 (5), e63907, 2013 | 61 | 2013 |
Stress preconditioning attenuates oxidative injury to the alveolar epithelium of the lung following haemorrhage in rats JF Pittet, LN Lu, T Geiser, H Lee, MA Matthay, WJ Welch The Journal of physiology 538 (2), 583-597, 2002 | 58 | 2002 |
The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation-Potential role for a reduction in reactive oxygen species generation (vol … J Hamacher, U Stammberger, J Roux Critical care medicine 38 (4), 1240-1240, 2010 | 51* | 2010 |
The lectin-like domain of tumor necrosis factor improves lung function after rat lung transplantation—Potential role for a reduction in reactive oxygen species generation J Hamacher, U Stammberger, J Roux, S Kumar, G Yang, C Xiong, ... Critical care medicine 38 (3), 871, 2010 | 51 | 2010 |
Sevoflurane but not propofol increases interstitial glycolysis metabolites availability during tourniquet-induced ischaemia–reperfusion M Carles, J Dellamonica, J Roux, D Lena, J Levraut, JF Pittet, P Boileau, ... British journal of anaesthesia 100 (1), 29-35, 2008 | 48 | 2008 |
Role of Small GTPases and αvβ5 Integrin in Pseudomonas aeruginosa–Induced Increase in Lung Endothelial Permeability MT Ganter, J Roux, G Su, SV Lynch, CS Deutschman, YG Weiss, ... American journal of respiratory cell and molecular biology 40 (1), 108-118, 2009 | 45 | 2009 |
Cytoprotective-Selective Activated Protein C Attenuates Pseudomonas aeruginosa–Induced Lung Injury in Mice N Bir, M Lafargue, M Howard, A Goolaerts, J Roux, M Carles, MJ Cohen, ... American journal of respiratory cell and molecular biology 45 (3), 632-641, 2011 | 42 | 2011 |
Transforming growth factor β1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a … J Roux, M Carles, H Koh, A Goolaerts, MT Ganter, BB Chesebro, ... Journal of Biological Chemistry 285 (7), 4278-4290, 2010 | 41 | 2010 |
IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK2/PI3K-dependent mechanism J Roux, CM McNicholas, M Carles, A Goolaerts, BT Houseman, ... The FASEB Journal 27 (3), 1095-1106, 2013 | 38 | 2013 |
Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors Y Zhu, N Bassoff, C Reinshagen, D Bhere, MO Nowicki, SE Lawler, ... Scientific reports 7 (1), 1-11, 2017 | 37 | 2017 |
PAI-1 is an essential component of the pulmonary host response during Pseudomonas aeruginosa pneumonia in mice A Goolaerts, M Lafargue, Y Song, B Miyazawa, M Arjomandi, M Carlès, ... Thorax 66 (9), 788-796, 2011 | 37 | 2011 |