Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosis BRG Gordon, Y Li, L Wang, A Sintsova, H Van Bakel, S Tian, WW Navarre, ... Proceedings of the National Academy of Sciences 107 (11), 5154-5159, 2010 | 246 | 2010 |
Beclin 1-independent autophagy induced by a Bcl-XL/Bcl-2 targeting compound, Z18 S Tian*, J Lin*, J Zhou, X Wang, Y Li, X Ren, W Yu, W Zhong, J Xiao, ... Autophagy 6 (8), 1032-1041, 2010 | 110 | 2010 |
Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells L Tao*, S Tian*, J Zhang*, Z Liu, L Robinson-McCarthy, SI Miyashita, ... Nature Microbiology 4 (10), 1760-1769, 2019 | 88* | 2019 |
Anticancer gold (I)–phosphine complexes as potent autophagy-inducing agents S Tian, FM Siu, SCF Kui, CN Lok, CM Che Chemical Communications 47 (33), 9318-9320, 2011 | 77 | 2011 |
Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation S Tian, K Muneeruddin, MY Choi, L Tao, RH Bhuiyan, Y Ohmi, ... PLoS Biology 16 (11), e2006951, 2018 | 68 | 2018 |
Proteomic analysis identifies membrane proteins dependent on the ER membrane protein complex S Tian*, Q Wu*, B Zhou, MY Choi, B Ding, W Yang, M Dong# Cell Reports 28 (10), 2517-2526. e5, 2019 | 56 | 2019 |
Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection P Chen, J Zeng, Z Liu, H Thaker, S Wang, S Tian, J Zhang, L Tao, ... Nature Communications 12 (1), 3748, 2021 | 47* | 2021 |
A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in Hela cells J Lin, Z Zheng, Y Li, W Yu, W Zhong, S Tian, F Zhao, X Ren, J Xiao, ... Autophagy 5 (3), 314-320, 2009 | 42 | 2009 |
Genome-wide CRISPR screen identifies Semaphorin 6A and 6B as receptors for Paeniclostridium sordellii toxin TcsL S Tian, Y Liu, H Wu, H Liu, J Zeng, MY Choi, H Chen, R Gerhard, ... Cell Host & Microbe 27 (5), 782-792. e7, 2020 | 31 | 2020 |
Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors X Xiong*, S Tian*, P Yang*, F Lebreton*, H Bao, K Sheng, L Yin, P Chen, ... Cell 185 (7), 1157-1171.e22, 2022 | 26 | 2022 |
LEC–BiFC: a new method for rapid assay of protein interaction J Lin, N Wang, Y Li, Z Liu, S Tian, L Zhao, Y Zheng, S Liu, S Li, C Jin, ... Biotechnic & Histochemistry 86 (4), 272-279, 2011 | 26 | 2011 |
Shiga Toxins: An Update on Host Factors and Biomedical Applications Y Liu, S Tian, H Thaker, M Dong Toxins 13 (3), 222, 2021 | 24 | 2021 |
A recurrent, homozygous EMC10 frameshift variant is associated with a syndrome of developmental delay with variable seizures and dysmorphic features DD Shao, R Straussberg, H Ahmed, A Khan, S Tian, RS Hill, RS Smith, ... Genetics in Medicine 23 (6), 1158-1162, 2021 | 18 | 2021 |
Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms S Tian*#, Y Liu*, E Appleton, H Wang, GM Church, M Dong# Cell Reports 38 (10), 110476, 2022 | 15 | 2022 |
CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor Y Xu, R Viswanatha, O Sitsel, D Roderer, H Zhao, C Ashwood, C Voelcker, ... Nature 610 (7931), 349-355, 2022 | 15 | 2022 |
Anticancer auranofin engages 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) as a target S Tian, FM Siu, CN Lok, YME Fung, CM Che# Metallomics 11 (11), 1925-1936, 2019 | 15 | 2019 |
Structure and conformational dynamics of Clostridioides difficile toxin A B Chen, S Basak, P Chen, C Zhang, K Perry, S Tian, C Yu, M Dong, ... Life Science Alliance 5 (6), 2022 | 11 | 2022 |
Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants S Tian#, X Xiong, J Zeng, S Wang, BJM Tremblay, P Chen, B Chen, M Liu, ... Nature Communications 13 (1), 1-19, 2022 | 10 | 2022 |
Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B Z Liu, S Zhang, P Chen, S Tian, J Zeng, K Perry, M Dong, R Jin Science Advances 7 (43), eabi4582, 2021 | 9 | 2021 |
CDKL3 promotes osteosarcoma progression by activating Akt/PKB A He, L Ma, Y Huang, H Zhang, W Duan, Z Li, T Fei, J Yuan, H Wu, L Liu, ... Life Science Alliance 3 (5), 2020 | 8 | 2020 |