Howard J Federoff
Howard J Federoff
Distinguished Professor of neurology, retired
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Mediation of poly (ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
SW Yu, H Wang, MF Poitras, C Coombs, WJ Bowers, HJ Federoff, ...
Science 297 (5579), 259-263, 2002
Plasma phospholipids identify antecedent memory impairment in older adults
M Mapstone, AK Cheema, MS Fiandaca, X Zhong, TR Mhyre, ...
Nature medicine 20 (4), 415-418, 2014
PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
B Zheng, Z Liao, JJ Locascio, KA Lesniak, SS Roderick, ML Watt, ...
Science translational medicine 2 (52), 52ra73-52ra73, 2010
Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: a case‐control study
MS Fiandaca, D Kapogiannis, M Mapstone, A Boxer, E Eitan, JB Schwartz, ...
Alzheimer's & Dementia 11 (6), 600-607. e1, 2015
Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss
AI Brooks, CA Chadwick, HA Gelbard, DA Cory-Slechta, HJ Federoff
Brain research 823 (1-2), 1-10, 1999
Synuclein activates microglia in a model of Parkinson's disease
X Su, KA Maguire-Zeiss, R Giuliano, L Prifti, K Venkatesh, HJ Federoff
Neurobiology of aging 29 (11), 1690-1701, 2008
Regulation of neuronal traits by a novel transcriptional complex
N Ballas, E Battaglioli, F Atouf, ME Andres, J Chenoweth, ME Anderson, ...
Neuron 31 (3), 353-365, 2001
Expression of bcl-2 from a defective herpes simplex virus–1 vector limits neuronal death in focal cerebral ischemia
MD Linnik, P Zahos, MD Geschwind, HJ Federoff
Stroke 26 (9), 1670-1675, 1995
A focus on the synapse for neuroprotection in Alzheimer disease and other dementias
P Coleman, H Federoff, R Kurlan
Neurology 63 (7), 1155-1162, 2004
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
BD Lee, JH Shin, J VanKampen, L Petrucelli, AB West, HS Ko, YI Lee, ...
Nature medicine 16 (9), 998-1000, 2010
Regulated release and polarized localization of brain-derived neurotrophic factor in hippocampal neurons
LJ Goodman, J Valverde, F Lim, MD Geschwind, HJ Federoff, AI Geller, ...
Molecular and Cellular Neuroscience 7 (3), 222-238, 1996
Nerve growth factor administration protects against experimental diabetic sensory neuropathy
SC Apfel, JC Arezzo, M Brownlee, H Federoff, JA Kessler
Brain research 634 (1), 7-12, 1994
Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death
H Wang, SW Yu, DW Koh, J Lew, C Coombs, W Bowers, HJ Federoff, ...
Journal of Neuroscience 24 (48), 10963-10973, 2004
Behavioral and neurochemical effects of wild-type and mutated human α-synuclein in transgenic mice
EK Richfield, MJ Thiruchelvam, DA Cory-Slechta, C Wuertzer, ...
Experimental neurology 175 (1), 35-48, 2002
Nerve growth factor prevents both neuroretinal programmed cell death and capillary pathology in experimental diabetes
HP Hammes, HJ Federoff, M Brownlee
Molecular Medicine 1, 527-534, 1995
Targeting microglial activation states as a therapeutic avenue in Parkinson’s disease
SR Subramaniam, HJ Federoff
Frontiers in aging neuroscience 9, 176, 2017
Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex …
MC Janelsins, MA Mastrangelo, S Oddo, FM LaFerla, HJ Federoff, ...
Journal of neuroinflammation 2, 1-12, 2005
Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins
M Jackson, W Song, MY Liu, L Jin, M Dykes-Hoberg, CG Lin, WJ Bowers, ...
Nature 410 (6824), 89-93, 2001
Hypoxia-inducible factor-1α mediates hypoxia-induced delayed neuronal death that involves p53
MW Halterman, CC Miller, HJ Federoff
Journal of Neuroscience 19 (16), 6818-6824, 1999
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice
MC Janelsins, MA Mastrangelo, KM Park, KL Sudol, WC Narrow, S Oddo, ...
The American journal of pathology 173 (6), 1768-1782, 2008
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