Peter K. Sorger

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Sandro Santagata MD PhDBWH Pathology | HMS Laboratory of Systems Pharmacology | HMS Department of SysBioVerified email at bics.bwh.harvard.edu
Mario NiepelRibon TherapeuticsVerified email at ribontx.com
Jia-Ren LinHarvard Medical School; Stanford University; National Taiwan UniversityVerified email at hms.harvard.edu
Marc HafnerGenentechVerified email at gene.com
Douglas LauffenburgerMITVerified email at mit.edu
Suzanne GaudetAssociate Director, Novartis Institutes for Biomedical ResearchVerified email at novartis.com
Jeremy L MuhlichDirector of Software Engineering, Harvard Medical School Laboratory of Systems PharmacologyVerified email at hms.harvard.edu
Benjamin IzarColumbia University Medical CenterVerified email at cumc.columbia.edu
Gregory J. BakerAmerican Cancer Society (ACS) Postdoctoral Fellow, Harvard Medical SchoolVerified email at hms.harvard.edu
John AlbeckProfessor of Molecular and Cellular Biology, University of California-DavisVerified email at ucdavis.edu
John A. BachmanFellow in Therapeutic Sciences, Harvard Medical SchoolVerified email at fas.harvard.edu
Adam C PalmerAssistant Professor, UNC-Chapel HillVerified email at unc.edu
Julio Saez RodriguezHeidelberg UniversityVerified email at uni-heidelberg.de
Leonidas AlexopoulosMechanical Engineering, National Technical University of AthensVerified email at mail.ntua.gr
John M BurkePresident and CEO, Applied BioMathVerified email at appliedbiomath.com
Ulrik B NielsenMerrimack PharmaceuticalsVerified email at merrimackpharma.com
Kevin JanesJohn Marshall Money Professor of Biomedical Engineering, University of VirginiaVerified email at virginia.edu
Viji Mythily DraviamQueen Mary University of LondonVerified email at qmul.ac.uk
Sabrina SpencerUniversity of Colorado-Boulder (Assistant Prof); Stanford University (Postdoc); MIT (PhD)Verified email at alum.mit.edu
Mohammad Fallahi-SichaniAssociate Professor of Biomedical Engineering, University of VirginiaVerified email at virginia.edu

Peter K. Sorger

Harvard Medical School

Verified email at hms.harvard.edu - Homepage

Systems Biology Cancer Pharmacology


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Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016	4150	2016
Cells on chips J El-Ali, PK Sorger, KF Jensen Nature 442 (7101), 403-411, 2006	2682	2006
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis SL Spencer, S Gaudet, JG Albeck, JM Burke, PK Sorger Nature 459 (7245), 428-432, 2009	1226	2009
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018	1103	2018
Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation PK Sorger, HRB Pelham Cell 54 (6), 855-864, 1988	1034	1988
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells LS Michel, V Liberal, A Chatterjee, R Kirchwegger, B Pasche, W Gerald, ... Nature 409 (6818), 355-359, 2001	949	2001
SARS-CoV-2 infection protects against rechallenge in rhesus macaques A Chandrashekar, J Liu, AJ Martinot, K McMahan, NB Mercado, L Peter, ... Science 369 (6505), 812-817, 2020	945	2020
Heat shock factor and the heat shock response PK Sorger Cell 65 (3), 363-366, 1991	825	1991
Physicochemical modelling of cell signalling pathways BB Aldridge, JM Burke, DA Lauffenburger, PK Sorger Nature cell biology 8 (11), 1195-1203, 2006	778	2006
Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks MJ Lee, SY Albert, AK Gardino, AM Heijink, PK Sorger, G MacBeath, ... Cell 149 (4), 780-794, 2012	750	2012
Electronic detection of DNA by its intrinsic molecular charge J Fritz, EB Cooper, S Gaudet, PK Sorger, SR Manalis Proceedings of the National Academy of sciences 99 (22), 14142-14146, 2002	715	2002
A role for the Adenomatous Polyposis Coli protein in chromosome segregation KB Kaplan, AA Burds, JR Swedlow, SS Bekir, PK Sorger, IS Näthke Nature cell biology 3 (4), 429-432, 2001	709	2001
Systems biology and combination therapy in the quest for clinical efficacy JB Fitzgerald, B Schoeberl, UB Nielsen, PK Sorger Nature chemical biology 2 (9), 458-466, 2006	694	2006
Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2 M Dobles, V Liberal, ML Scott, R Benezra, PK Sorger Cell 101 (6), 635-645, 2000	658	2000
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis KA Janes, JG Albeck, S Gaudet, PK Sorger, DA Lauffenburger, MB Yaffe Science 310 (5754), 1646-1653, 2005	640	2005
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs M Hafner, M Niepel, M Chung, PK Sorger Nature methods 13 (6), 521-527, 2016	629	2016
Combination cancer therapy can confer benefit via patient-to-patient variability without drug additivity or synergy AC Palmer, PK Sorger Cell 171 (7), 1678-1691. e13, 2017	605	2017
Heat shock factor is regulated differently in yeast and HeLa cells PK Sorger, MJ Lewis, HRB Pelham Nature 329 (6134), 81-84, 1987	600	1987
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah, S Santagata, PK Sorger elife 7, e31657, 2018	580	2018
Timing and checkpoints in the regulation of mitotic progression P Meraldi, VM Draviam, PK Sorger Developmental cell 7 (1), 45-60, 2004	564	2004

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