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Andreas Reichel
Andreas Reichel
Bayer AG
Verified email at bayer.com
Title
Cited by
Cited by
Year
Interaction of Poly(butylcyanoacrylate) Nanoparticles with the Blood-Brain Barrier in vivo and in vitro
RN Alyaudtin, A Reichel, R Löbenberg, P Ramge, J Kreuter, DJ Begley
Journal of drug targeting 9 (3), 209-221, 2001
2502001
Addressing central nervous system (CNS) penetration in drug discovery: basics and implications of the evolving new concept
A Reichel
Chemistry & biodiversity 6 (11), 2030-2049, 2009
1892009
Closing the gaps: a full scan of the intestinal expression of p-glycoprotein, breast cancer resistance protein, and multidrug resistance-associated protein 2 in male and female …
C MacLean, U Moenning, A Reichel, G Fricker
Drug Metabolism and Disposition 36 (7), 1249-1254, 2008
1722008
An overview of in vitro techniques for blood-brain barrier studies
A Reichel, DJ Begley, NJ Abbott
The Blood-Brain Barrier: Biology and Research Protocols, 307-324, 2003
1712003
The role of blood-brain barrier studies in the pharmaceutical industry
A Reichel
Current drug metabolism 7 (2), 183-203, 2006
1702006
The Lab Oddity Prevails: Discovery of Pan‐CDK Inhibitor (R)‐S‐Cyclopropyl‐S‐(4‐{[4‐{[(1R,2R)‐2‐hydroxy‐1‐methylpropyl]oxy}‐5‐(trifluoromethyl)pyrimidin‐2 …
U Lücking, R Jautelat, M Krüger, T Brumby, P Lienau, M Schäfer, H Briem, ...
ChemMedChem 8 (7), 1067-1085, 2013
1672013
Potential of immobilized artificial membranes for predicting drug penetration across the blood− brain barrier
A Reichel, DJ Begley
Pharmaceutical research 15, 1270-1274, 1998
1621998
Drug resistance in epilepsy: the role of the blood–brain barrier
NJ Abbott, EU Khan, CMS Rollinson, A Reichel, D Janigro, ...
Mechanisms of Drug Resistance in Epilepsy: Novartis Foundation Symposium 243 …, 2002
1602002
Mechanism-based inhibition: deriving KI and kinact directly from time-dependent IC50 values
BF Krippendorff, R Neuhaus, P Lienau, A Reichel, W Huisinga
SLAS Discovery 14 (8), 913-923, 2009
1542009
Straightforward strategies for the preparation of NH-sulfoximines: a serendipitous story
JA Bull, L Degennaro, R Luisi
Synlett 28 (19), 2525-2538, 2017
1222017
Affinity for the P-glycoprotein efflux pump at the blood-brain barrier may explain the lack of CNS side-effects of modern antihistamines
M Chishty, A Reichel, J Siva, NJ Abbott, DJ Begley
Journal of drug targeting 9 (3), 223-228, 2001
1082001
Characterization of cytochrome P450 protein expression along the entire length of the intestine of male and female rats
D Mitschke, A Reichel, G Fricker, U Moenning
Drug Metabolism and Disposition 36 (6), 1039-1045, 2008
972008
Optimizing classification of drug-drug interaction potential for CYP450 isoenzyme inhibition assays in early drug discovery
BF Krippendorff, P Lienau, A Reichel, W Huisinga
Journal of biomolecular screening 12 (1), 92-99, 2007
742007
Pharmacokinetics in drug discovery: an exposure-centred approach to optimising and predicting drug efficacy and safety
A Reichel, P Lienau
New approaches to drug discovery, 235-260, 2016
702016
Piperidine renin inhibitors: from leads to drug candidates
HP Märki, A Binggeli, B Bittner, V Bohner-Lang, V Breu, D Bur, ...
Il Farmaco 56 (1-2), 21-27, 2001
672001
Development and application of physiologically based pharmacokinetic‐modeling tools to support drug discovery
C Lüpfert, A Reichel
Chemistry & biodiversity 2 (11), 1462-1486, 2005
662005
Piperazine derivatives that destabilize androgen receptors
A Cleve, C Huwe, V Schulze, H Morack, D Zopf, J Hoffmann, A Reichel
US Patent 6,861,432, 2005
472005
N-glycosylation of ABC transporters is associated with functional activity in sandwich-cultured rat hepatocytes
V Draheim, A Reichel, W Weitschies, U Moenning
European journal of pharmaceutical sciences 41 (2), 201-209, 2010
462010
A probabilistic approach to classifying metabolic stability
A Schwaighofer, T Schroeter, S Mika, K Hansen, A Ter Laak, P Lienau, ...
Journal of chemical information and modeling 48 (4), 785-796, 2008
462008
17α-ALKYL-17β-OXY-ESTRATRIENES AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION, USE OF THE 17α-ALKYL-17β-OXY-ESTRATRIENES FOR THE PRODUCTION OF PHARMACEUTICAL AGENTS AS WELL AS …
R Bohlmann, N Heinrich, R Jautelat, J Kroll, O Petrov, A Reichel, ...
US Patent 7,018,994, 2006
402006
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