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Isaac Kohane
Isaac Kohane
Harvard Medical School, Children's Hospital, Brigham and Women's Hospital
Verified email at hms.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
72482008
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
24242018
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ...
Proceedings of the National Academy of Sciences 100 (14), 8466-8471, 2003
23812003
Machine learning in medicine
A Rajkomar, J Dean, I Kohane
New England Journal of Medicine 380 (14), 1347-1358, 2019
23782019
Gene regulation and DNA damage in the ageing human brain
T Lu, Y Pan, SY Kao, C Li, I Kohane, J Chan, BA Yankner
Nature 429 (6994), 883-891, 2004
21062004
Artificial intelligence in healthcare
KH Yu, AL Beam, IS Kohane
Nature biomedical engineering 2 (10), 719-731, 2018
18912018
Big data and machine learning in health care
AL Beam, IS Kohane
Jama 319 (13), 1317-1318, 2018
14672018
Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements
AJ Butte, IS Kohane
Biocomputing 2000, 418-429, 1999
14021999
Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease
National Research Council, Division on Earth, Life Studies, ...
National Academies Press, 2011
1285*2011
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
SL Carter, AC Eklund, IS Kohane, LN Harris, Z Szallasi
Nature genetics 38 (9), 1043-1048, 2006
12562006
A mega-analysis of genome-wide association studies for major depressive disorder
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium
Molecular psychiatry 18 (4), 2013
12382013
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)
SN Murphy, G Weber, M Mendis, V Gainer, HC Chueh, S Churchill, ...
Journal of the American Medical Informatics Association 17 (2), 124-130, 2010
10292010
Safety of the BNT162b2 mRNA Covid-19 vaccine in a nationwide setting
N Barda, N Dagan, Y Ben-Shlomo, E Kepten, J Waxman, R Ohana, ...
New England Journal of Medicine 385 (12), 1078-1090, 2021
9472021
Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study
N Barda, N Dagan, C Cohen, MA Hernán, M Lipsitch, IS Kohane, BY Reis, ...
The Lancet 398 (10316), 2093-2100, 2021
8662021
Discovering statistically significant pathways in expression profiling studies
L Tian, SA Greenberg, SW Kong, J Altschuler, IS Kohane, PJ Park
Proceedings of the National Academy of Sciences 102 (38), 13544-13549, 2005
8222005
Adversarial attacks on medical machine learning
SG Finlayson, JD Bowers, J Ito, JL Zittrain, AL Beam, IS Kohane
Science 363 (6433), 1287-1289, 2019
8182019
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
AJ Butte, P Tamayo, D Slonim, TR Golub, IS Kohane
Proceedings of the National Academy of Sciences 97 (22), 12182-12186, 2000
7972000
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology
J Loscalzo, I Kohane, AL Barabasi
Molecular systems biology 3 (1), 124, 2007
6802007
Genetic misdiagnoses and the potential for health disparities
AK Manrai, BH Funke, HL Rehm, MS Olesen, BA Maron, P Szolovits, ...
New England Journal of Medicine 375 (7), 655-665, 2016
6762016
SMART on FHIR: a standards-based, interoperable apps platform for electronic health records
JC Mandel, DA Kreda, KD Mandl, IS Kohane, RB Ramoni
Journal of the American Medical Informatics Association 23 (5), 899-908, 2016
6622016
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Articles 1–20