David Meyerholz
David Meyerholz
Professor, Department of Pathology, Carver College of Medicine, University of Iowa
Verified email at - Homepage
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Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice
R Channappanavar, AR Fehr, R Vijay, M Mack, J Zhao, DK Meyerholz, ...
Cell host & microbe 19 (2), 181-193, 2016
Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2
J Netland, DK Meyerholz, S Moore, M Cassell, S Perlman
Journal of virology 82 (15), 7264-7275, 2008
Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus
PB McCray Jr, L Pewe, C Wohlford-Lenane, M Hickey, L Manzel, L Shi, ...
Journal of virology 81 (2), 813-821, 2007
Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection
R Channappanavar, C Fett, M Mack, PP Ten Eyck, DK Meyerholz, ...
The Journal of Immunology 198 (10), 4046-4053, 2017
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs
CS Rogers, DA Stoltz, DK Meyerholz, LS Ostedgaard, T Rokhlina, PJ Taft, ...
Science 321 (5897), 1837-1841, 2008
Origins of cystic fibrosis lung disease
DA Stoltz, DK Meyerholz, MJ Welsh
New England Journal of Medicine 372 (4), 351-362, 2015
Principles for valid histopathologic scoring in research
KN Gibson-Corley, AK Olivier, DK Meyerholz
Veterinary pathology 50 (6), 1007-1015, 2013
Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors
JP Dassie, X Liu, GS Thomas, RM Whitaker, KW Thiel, KR Stockdale, ...
Nature biotechnology 27 (9), 839-846, 2009
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes
R Channappanavar, AR Fehr, J Zheng, C Wohlford-Lenane, ...
The Journal of clinical investigation 129 (9), 3625-3639, 2019
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth
DA Stoltz, DK Meyerholz, AA Pezzulo, S Ramachandran, MP Rogan, ...
Science translational medicine 2 (29), 29ra31-29ra31, 2010
Airway memory CD4+ T cells mediate protective immunity against emerging respiratory coronaviruses
J Zhao, J Zhao, AK Mangalam, R Channappanavar, C Fett, DK Meyerholz, ...
Immunity 44 (6), 1379-1391, 2016
Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4
K Li, C Wohlford-Lenane, S Perlman, J Zhao, AK Jewell, LR Reznikov, ...
The Journal of infectious diseases 213 (5), 712-722, 2016
Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection
R Channappanavar, C Fett, J Zhao, DK Meyerholz, S Perlman
Journal of virology 88 (19), 11034-11044, 2014
Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment
J Sun, Z Zhuang, J Zheng, K Li, RLY Wong, D Liu, J Huang, J He, A Zhu, ...
Cell 182 (3), 734-743. e5, 2020
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus
AS Kondratowicz, NJ Lennemann, PL Sinn, RA Davey, CL Hunt, ...
Proceedings of the National Academy of Sciences 108 (20), 8426-8431, 2011
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice
J Zheng, LYR Wong, K Li, AK Verma, ME Ortiz, C Wohlford-Lenane, ...
Nature 589 (7843), 603-607, 2021
Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis
X Sun, H Sui, JT Fisher, Z Yan, X Liu, HJ Cho, NS Joo, Y Zhang, W Zhou, ...
The Journal of clinical investigation 120 (9), 3149-3160, 2010
Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae
BR O'Keefe, B Giomarelli, DL Barnard, SR Shenoy, PKS Chan, ...
Journal of virology 84 (5), 2511-2521, 2010
Airway acidification initiates host defense abnormalities in cystic fibrosis mice
VS Shah, DK Meyerholz, XX Tang, L Reznikov, M Abou Alaiwa, SE Ernst, ...
Science 351 (6272), 503-507, 2016
The porcine lung as a potential model for cystic fibrosis
CS Rogers, WM Abraham, KA Brogden, JF Engelhardt, JT Fisher, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (2 …, 2008
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