Immune checkpoint inhibitors: new insights and current place in cancer therapy NM La‐Beck, GW Jean, C Huynh, SK Alzghari, DB Lowe Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 35 (10 …, 2015 | 247 | 2015 |
Combined vaccine+ axitinib therapy yields superior antitumor efficacy in a murine melanoma model A Bose, DB Lowe, A Rao, WJ Storkus Melanoma research 22 (3), 236-243, 2012 | 70 | 2012 |
Chronic inflammation and immunologic-based constraints in malignant disease DB Lowe, WJ Storkus Immunotherapy 3 (10), 1265-1274, 2011 | 69 | 2011 |
Towards progress on DNA vaccines for cancer DB Lowe, MH Shearer, CA Jumper, RC Kennedy Cellular and molecular life sciences 64, 2391-2403, 2007 | 53 | 2007 |
Vaccines targeting tumor blood vessel antigens promote CD8+ T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice X Zhao, A Bose, H Komita, JL Taylor, N Chi, DB Lowe, H Okada, Y Cao, ... The Journal of Immunology 188 (4), 1782-1788, 2012 | 52 | 2012 |
Vaccines and immunotherapeutics for the treatment of malignant disease JF Aldrich, DB Lowe, MH Shearer, RE Winn, CA Jumper, RC Kennedy Journal of Immunology Research 2010, 2010 | 52 | 2010 |
Intratumoral IL-12 gene therapy results in the crosspriming of Tc1 cells reactive against tumor-associated stromal antigens X Zhao, A Bose, H Komita, JL Taylor, M Kawabe, N Chi, L Spokas, ... Molecular therapy 19 (4), 805-814, 2011 | 49 | 2011 |
DNA vaccines: successes and limitations in cancer and infectious disease DB Lowe, MH Shearer, RC Kennedy Journal of cellular biochemistry 98 (2), 235-242, 2006 | 49 | 2006 |
Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma DB Lowe, A Bose, JL Taylor, H Tawbi, Y Lin, JM Kirkwood, WJ Storkus Oncoimmunology 3 (2), e27589, 2014 | 48 | 2014 |
A NOD/SCID tumor model for human ovarian cancer that allows tracking of tumor progression through the biomarker Sp17 M Chiriva-Internati, F Grizzi, JA Weidanz, R Ferrari, Y Yuefei, B Velez, ... Journal of immunological methods 321 (1-2), 86-93, 2007 | 37 | 2007 |
Pathogenetic features and current management of glioblastoma HM Nguyen, K Guz-Montgomery, DB Lowe, D Saha Cancers 13 (4), 856, 2021 | 30 | 2021 |
Dendritic cell vaccine therapy for colorectal cancer AL Wooster, LH Girgis, H Brazeale, TS Anderson, LM Wood, DB Lowe Pharmacological research 164, 105374, 2021 | 30 | 2021 |
Dendritic cell vaccines targeting tumor blood vessel antigens in combination with dasatinib induce therapeutic immune responses in patients with checkpoint-refractory advanced … WJ Storkus, D Maurer, Y Lin, F Ding, A Bose, D Lowe, A Rose, M DeMark, ... Journal for immunotherapy of cancer 9 (11), 2021 | 29 | 2021 |
TCR-like antibody drug conjugates mediate killing of tumor cells with low peptide/HLA targets DB Lowe, CK Bivens, AS Mobley, CE Herrera, AL McCormick, T Wichner, ... MAbs 9 (4), 603-614, 2017 | 28 | 2017 |
Extranodal induction of therapeutic immunity in the tumor microenvironment after intratumoral delivery of Tbet gene-modified dendritic cells L Chen, JL Taylor, NC Sabins, DB Lowe, Y Qu, Z You, WJ Storkus Cancer gene therapy 20 (8), 469-477, 2013 | 27 | 2013 |
SV40 association with human malignancies and mechanisms of tumor immunity by large tumor antigen DB Lowe, MH Shearer, CA Jumper, RC Kennedy Cellular and molecular life sciences 64, 803-814, 2007 | 19 | 2007 |
Fcγ receptors play a dominant role in protective tumor immunity against a virus-encoded tumor-specific antigen in a murine model of experimental pulmonary metastases DB Lowe, MH Shearer, CA Jumper, RK Bright, RC Kennedy Journal of virology 81 (3), 1313-1318, 2007 | 17 | 2007 |
Disrupting cancer angiogenesis and immune checkpoint networks for improved tumor immunity TS Anderson, AL Wooster, SL Piersall, IF Okpalanwaka, DB Lowe Seminars in cancer biology 86, 981-996, 2022 | 16 | 2022 |
In vitro simian virus 40 large tumor antigen expression correlates with differential immune responses following DNA immunization DB Lowe, MH Shearer, JA Tarbox, HS Kang, CA Jumper, RK Bright, ... Virology 332 (1), 28-37, 2005 | 14 | 2005 |
Role of the innate immune response and tumor immunity associated with simian virus 40 large tumor antigen DB Lowe, MH Shearer, JF Aldrich, RE Winn, CA Jumper, RC Kennedy Journal of virology 84 (19), 10121-10130, 2010 | 13 | 2010 |