Sulforaphane induces cell cycle arrest and apoptosis in acute lymphoblastic leukemia cells K Suppipat, CS Park, Y Shen, X Zhu, HD Lacorazza PloS one 7 (12), e51251, 2012 | 118 | 2012 |
Ablation of Vacuole Protein Sorting 18 (Vps18) Gene Leads to Neurodegeneration and Impaired Neuronal Migration by Disrupting Multiple Vesicle Transport Pathways to Lysosomes*♦ C Peng, J Ye, S Yan, S Kong, Y Shen, C Li, Q Li, Y Zheng, K Deng, T Xu, ... Journal of Biological Chemistry 287 (39), 32861-32873, 2012 | 50 | 2012 |
G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol T Yamada, CS Park, Y Shen, KR Rabin, HD Lacorazza Leukemia research 38 (2), 210-217, 2014 | 47 | 2014 |
A KLF4-DYRK2–mediated pathway regulating self-renewal in CML stem cells CS Park, AH Lewis, TJ Chen, CS Bridges, Y Shen, K Suppipat, M Puppi, ... Blood, The Journal of the American Society of Hematology 134 (22), 1960-1972, 2019 | 42 | 2019 |
Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway Y Shen, CS Park, K Suppipat, TA Mistretta, M Puppi, TM Horton, K Rabin, ... Leukemia 31 (6), 1314-1324, 2017 | 36 | 2017 |
Krüppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen CS Park, PH Lee, T Yamada, A Burns, Y Shen, M Puppi, HD Lacorazza Journal of leukocyte biology 91 (5), 739, 2012 | 34 | 2012 |
Role of the reprogramming factor KLF4 in blood formation CS Park, Y Shen, A Lewis, HD Lacorazza Journal of Leucocyte Biology 99 (5), 673-685, 2016 | 33 | 2016 |
Differential roles of KLF4 in the development and differentiation of CD8+ T cells M Mamonkin, Y Shen, PH Lee, M Puppi, CS Park, HD Lacorazza Immunology letters 156 (1-2), 94-101, 2013 | 25 | 2013 |
Cancer cell-intrinsic resistance to BiTE therapy is mediated by loss of CD58 costimulation and modulation of the extrinsic apoptotic pathway Y Shen, JS Eng, F Fajardo, L Liang, C Li, P Collins, D Tedesco, ... Journal for immunotherapy of cancer 10 (3), 2022 | 24 | 2022 |
Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia Y Shen, TJ Chen, HD Lacorazza Experimental hematology 53, 16-25, 2017 | 24 | 2017 |
PP6 controls T cell development and homeostasis by negatively regulating distal TCR signaling J Ye, H Shi, Y Shen, C Peng, Y Liu, C Li, K Deng, J Geng, T Xu, Y Zhuang, ... The Journal of Immunology 194 (4), 1654-1664, 2015 | 22 | 2015 |
G0S2 modulates homeostatic proliferation of naïve CD8+ T cells and inhibits oxidative phosphorylation in mitochondria PH Lee, T Yamada, CS Park, Y Shen, M Puppi, HD Lacorazza Immunology and cell biology 93 (7), 605-615, 2015 | 16 | 2015 |
Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia TJ Chen, W Du, JJ Junco, CS Bridges, Y Shen, M Puppi, KR Rabin, ... Oncotarget 12 (18), 1787, 2021 | 8 | 2021 |
Krüppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen C Shik Park, PH Lee, T Yamada, A Burns, Y Shen, M Puppi, ... Journal of Leukocyte Biology 91 (5), 739-750, 2012 | 3 | 2012 |
Chemical inhibition of the macrophage inhibitor factor (MIF) induces cell cycle arrest and apoptosis in lymphoid and myeloid leukemia A Lewis, CS Park, Y Shen, NK Lee, HD Lacorazza Blood, The Journal of the American Society of Hematology 130 (Suppl_1), 1329 …, 2017 | 2 | 2017 |
KLF4 promotes self-renewal by repressing DYRK2-mediated degradation of c-Myc in leukemic stem cells: development of targeted therapy CS Park, Y Shen, K Suppipat, J Tomolonis, M Puppi, TA Mistretta, L Ma, ... Cancer research 76 (14_Supplement), 3334-3334, 2016 | 1 | 2016 |
Genetic screens identify T cell co-stimulation as a key modifier of the redirected cytotoxicity of bispecific T cell engager (BiTE®) molecules Y Shen, P Collins, J Eng, F Fajardo, W Zhong, O Nolan-Stevaux Cancer Research 80 (16_Supplement), 6714-6714, 2020 | | 2020 |
Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia TJ Chen, Y Shen, CS Bridges, CS Park, JJ Junco, KR Rabin, ... Blood 134, 3889, 2019 | | 2019 |
KLF4 Represses DYRK2 Inhibition of Self-renewal and Survival Through c-Myc and p53 in Leukemia Stem/Progenitor Cells CS Park, AH Lewis, TJ Chen, CS Bridges, Y Shen, K Suppipat, M Puppi, ... | | 2019 |
Pharmacologic inhibition of SIAH2 stabilizes DYRK2 and inhibits survival and self-renewal in chronic myeloid leukemia (CML) leukemic stem cells CS Park, Y Shen, A Lewis, K Suppipat, M Puppi, J Tomolonis, T Chen, ... Cancer Research 78 (13_Supplement), 145-145, 2018 | | 2018 |